(Q40835601)

24 September 2017

title

2-(Acyloxy)ethylphosphonate analogues of prenyl pyrophosphates: synthesis and biological characterization (English)

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24 September 2017

Cermak DM

1

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24 September 2017

Wiemer DF

series ordinal

2

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24 September 2017

Lewis K

series ordinal

3

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24 September 2017

Hohl RJ

series ordinal

4

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24 September 2017

language of work or name

English

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publication date

1 December 2000

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Bioorganic & Medicinal Chemistry

24 September 2017

published in

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24 September 2017

volume

8

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24 September 2017

issue

12

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24 September 2017

page(s)

2729-2737

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Protein prenylation, et cetera: signal transduction in two dimensions

24 September 2017

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Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development

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All ras proteins are polyisoprenylated but only some are palmitoylated

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Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

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Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides

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Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor

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Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

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Probing the hydrophobic pocket of farnesyltransferase: aromatic substitution of CAAX peptidomimetics leads to highly potent inhibitors

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Isolation and structure of chaetomellic acids A and B from Chaetomella acutiseta: farnesyl pyrophosphate mimic inhibitors of ras farnesyl-protein transferase

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Actinoplanic Acid A: A Macrocyclic Polycarboxylic Acid Which Is a Potent Inhibitor of Ras Farnesyl-Protein Transferase

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Farnesyl diphosphate-based inhibitors of Ras farnesyl protein transferase

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Synthesis of Farnesol Analogues through Cu(I)-Mediated Displacements of Allylic THP Ethers by Grignard Reagents

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Steady-state kinetic mechanism of Ras farnesyl:protein transferase

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Cuprate-Mediated Synthesis and Biological Evaluation of Cyclopropyl- and tert-Butylfarnesyl Diphosphate Analogs

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Farnesyl-derived inhibitors of ras farnesyl transferase

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Photoactive Analogs of Farnesyl Pyrophosphate Containing Benzoylbenzoate Esters: Synthesis and Application to Photoaffinity Labeling of Yeast Protein Farnesyltransferase

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Useful procedures for the oxidation of alcohols involving pyridinium dichromate in aprotic media

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The Wittig olefination reaction and modifications involving phosphoryl-stabilized carbanions. Stereochemistry, mechanism, and selected synthetic aspects

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The Horner-Wadsworth-Emmons modification of the Wittig reaction using triethylamine and lithium or magnesium salts

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7 January 2021

Villiramulins A and B: new phenol derivatives from Piper villiramulum

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7 January 2021

Notes- A Convenient Synthesis of Water-Soluble Carbodiimides

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7 January 2021

A rapid and convenient filter-binding assay for ras p21 processing enzyme farnesyltransferase

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Protein farnesyltransferase: measurement of enzymatic activity in 96-well format using TopCount microplate scintillation counting technology

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Aluminium-chloride-promoted reactions of ethyl acrylate with olefins

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10.1016/S0968-0896(00)00212-1

Identifiers

DOI

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24 September 2017

1 reference