(Q40852425)

English

Increased sensitivity to chromatid aberration induction by bleomycin and neocarzinostatin results from alterations in a DNA damage response pathway

scientific article published on September 2000

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scholarly article

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Europe PubMed Central

24 September 2017

Increased sensitivity to chromatid aberration induction by bleomycin and neocarzinostatin results from alterations in a DNA damage response pathway (English)

1 reference

Europe PubMed Central

24 September 2017

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author name string

Allio T

1

1 reference

Europe PubMed Central

24 September 2017

Preston RJ

2

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Europe PubMed Central

24 September 2017

language of work or name

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publication date

1 September 2000

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Europe PubMed Central

24 September 2017

Mutation Research

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Europe PubMed Central

24 September 2017

453

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Europe PubMed Central

24 September 2017

1

1 reference

Europe PubMed Central

24 September 2017

5-15

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Europe PubMed Central

24 September 2017

p53 mutations in human cancers

1 reference

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7 January 2021

BRCA1 required for transcription-coupled repair of oxidative DNA damage

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7 January 2021

Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells

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7 January 2021

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

1 reference

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7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

1 reference

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Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

1 reference

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7 January 2021

The relationship between p53 status, DNA repair and chromatid aberration induction in G2 mouse embryo fibroblast cells treated with bleomycin.

1 reference

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7 January 2021

p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

1 reference

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

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7 January 2021

Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia

1 reference

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7 January 2021

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

1 reference

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7 January 2021

Double strand break repair

1 reference

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7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

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7 January 2021

The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction.

1 reference

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7 January 2021

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

1 reference

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7 January 2021

Transcriptional activation by BRCA1

1 reference

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7 January 2021

Transcriptional activation functions in BRCA2

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Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents.

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Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to adriamycin and ultraviolet radiation

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The BRCA2 gene product functionally interacts with p53 and RAD51

1 reference

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7 January 2021

BRCA1 regulates p53-dependent gene expression

1 reference

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7 January 2021

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

1 reference

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7 January 2021

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

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7 January 2021

Signalling to p53: where does it all start?

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7 January 2021

Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation

1 reference

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The use of inhibitors of DNA-repair in the study of the mechanisms of induction of chromosome aberrations

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7 January 2021

Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells.

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7 January 2021

Implication of DNA-dependent protein kinase in an early, essential, local phosphorylation event during end-joining of DNA double-strand breaks in vitro

1 reference

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7 January 2021

Identification of thymidine-5'-aldehyde at DNA strand breaks induced by neocarzinostatin chromophore

1 reference

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7 January 2021

DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes

1 reference

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7 January 2021

Mutation assay at the thymidine kinase locus in diploid human lymphoblasts

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7 January 2021

Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia

1 reference

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7 January 2021

Chromosomal breakage correlates with delayed lethality in normal and ataxia telangiectasia cell lines treated with bleomycin

1 reference

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7 January 2021

Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation

1 reference

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7 January 2021

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

1 reference

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7 January 2021

Mutations in the p53 and SCID genes cooperate in tumorigenesis.

1 reference

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7 January 2021

Identifiers

10.1016/S0027-5107(00)00030-0

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

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