(Q40855580)

24 September 2017

Dual role of epoxide hydratase in both activation and inactivation of benzo(a)pyrene (English)

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24 September 2017

3

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24 September 2017

P Bentley

1

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PubMed ID

341851

24 September 2017

F Oesch

series ordinal

2

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24 September 2017

1 December 1977

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24 September 2017

Archives of Toxicology

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24 September 2017

39

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24 September 2017

65-75

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24 September 2017

1-2

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https://scigraph.springernature.com/pub.10.1007/bf00343276

24 September 2017

0 references

cites work

Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes

1 reference

12 December 2020

Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols

1 reference

12 December 2020

Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells

1 reference

12 December 2020

Purification of rat liver epoxide hydratase to apparent homogeneity

1 reference

12 December 2020

High-pressure liquid chromatographic analysis of benzo(alpha)pyrene metabolism and covalent binding and the mechanism of action of 7,8-benzoflavone and 1,2-epoxy-3,3,3-trichloropropane

1 reference

12 December 2020

Epoxides metabolically produced from some known carcinogens and from some clinically used drugs. I. Differences in mutagenicity

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12 December 2020

Epoxides derived from various polycyclic hydrocarbons as substrates of homogeneous and microsome-bound epoxide hydratase. A general assay and kinetic properties

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12 December 2020

Prevention of benzo(a)pyrene-induced mutagenicity by homogeneous epoxide hydratase

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12 December 2020

Effects of Inducers and Epoxide Hydrase on the Metabolism of Benzo[ a ]pyrene by Liver Microsomes and a Reconstituted System: Analysis by High Pressure Liquid Chromatography

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12 December 2020

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

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12 December 2020

Metabolism of benzo[a]pyrene. Effect of substrate concentration and 3-methylcholanthrene pretreatment on hepatic metabolism by microsomes from rats and mice

1 reference

12 December 2020

Phenolic benzo(a)pyrene metabolites are mutagens

1 reference

12 December 2020

Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides

1 reference

12 December 2020

Exceptional mutagenicity of a benzo[a]pyrene diol epoxide in cultured mammalian cells

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12 December 2020

Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

1 reference

12 December 2020

A rapid assay for epoxide hydratase activity with benzo (a)pyrene 4,5-(K-region)-oxide as substrate

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00343276

1 reference

24 September 2017

1 reference

PubMed ID

341851