(Q40857868)

24 September 2017

Choosing anticancer drug targets in the postgenomic era. (English)

1 reference

24 September 2017

Kaelin WG Jr

1

1 reference

PMCID

409873

24 September 2017

language of work or name

English

0 references

publication date

1 December 1999

1 reference

Journal of Clinical Investigation

24 September 2017

1 reference

24 September 2017

104

1 reference

24 September 2017

11

1 reference

24 September 2017

1503-1506

1 reference

Creation of human tumour cells with defined genetic elements

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

The emerging p53 gene family

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Integrating genetic approaches into the discovery of anticancer drugs

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Cancer-susceptibility genes. Gatekeepers and caretakers

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

How many mutations are required for tumorigenesis? Implications from human cancer data

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

DNA tumor virus transforming proteins and the cell cycle

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Perturbation of cell cycle regulators in human cancer.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Tumour suppression by the human von Hippel-Lindau gene product

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Role of the retinoblastoma protein in the pathogenesis of human cancer

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Tumor surveillance via the ARF-p53 pathway.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=409873

Gene deletion: a new target for cancer chemotherapy

19 August 2018

1 reference

12 December 2020

p53 Mutation and MDM2 amplification in human soft tissue sarcomas

1 reference

12 December 2020

p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective

1 reference

12 December 2020

Negative control elements of the cell cycle in human tumors

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI8888

1 reference

24 September 2017

1 reference

24 September 2017

1 reference

PMCID

409873