(Q408598)

CXCR chemokine receptor binding

1 reference

31 October 2017

The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

chemoattractant activity

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

IBA

growth factor activity

1 reference

8 April 2019

signaling receptor binding

1 reference

8 April 2019

Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

6 references

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

WNK1 kinase balances T cell adhesion versus migration in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

extracellular exosome

external side of plasma membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

collagen-containing extracellular matrix

HDA

1 reference

8 April 2019

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

negative regulation of leukocyte tethering or rolling

HDA

biological process

1 reference

8 April 2019

CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

regulation of calcium ion transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of endothelial cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of cell migration

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

chemokine-mediated signaling pathway

1 reference

31 October 2017

The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

adult locomotory behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

response to mechanical stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

response to peptide hormone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of monocyte chemotaxis

1 reference

8 April 2019

Monocyte migration and LFA-1-mediated attachment to brain microvascular endothelia is regulated by SDF-1 alpha through Lyn kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

cellular calcium ion homeostasis

1 reference

8 April 2019

Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

8 April 2019

The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of axon extension involved in axon guidance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

telencephalon cell migration

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

4 references

8 April 2019

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

regulation of actin polymerization or depolymerization

1 reference

8 April 2019

The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of calcium ion import

TAS

1 reference

8 April 2019

Human galectin-3 is a novel chemoattractant for monocytes and macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

Specific activation of leukocyte beta2 integrins lymphocyte function-associated antigen-1 and Mac-1 by chemokines mediated by distinct pathways via the alpha subunit cytoplasmic domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of dopamine secretion

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

animal organ regeneration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

31 October 2017

CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

negative regulation of leukocyte apoptotic process

1 reference

31 October 2017

Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

response to radiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of T cell migration

1 reference

8 April 2019

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

positive regulation of cell adhesion

1 reference

8 April 2019

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

induction of positive chemotaxis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

response to ultrasound

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

antimicrobial humoral immune response mediated by antimicrobial peptide

1 reference

31 October 2017

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

1 reference

31 October 2017

Crystal structures of human alpha-defensins HNP4, HD5, and HD6

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

detection of temperature stimulus involved in sensory perception of pain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

detection of mechanical stimulus involved in sensory perception of pain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

2 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

1 reference

8 April 2019

Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

chemokine (C-X-C motif) ligand 12 signaling pathway

1 reference

8 April 2019

WNK1 kinase balances T cell adhesion versus migration in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

chemokine-mediated signaling pathway

IMP

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

cellular response to chemokine

IBA

1 reference

8 April 2019

WNK1 kinase balances T cell adhesion versus migration in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

negative regulation of dendritic cell apoptotic process

IMP

1 reference

8 April 2019

Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061

http://purl.uniprot.org/uniprot/P48061

Gene Atlas image

PBB GE CXCL12 209687 at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

stated in

Identifiers.org

Identifiers

MeSH descriptor ID

C515255

subject named as

CXCL12 protein, human

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016