(Q40861592)

24 September 2017

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title

Protein binding and stereoselectivity of nonsteroidal anti-inflammatory drugs (English)

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24 September 2017

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F Lapicque

1

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24 September 2017

N Muller

2

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24 September 2017

E Payan

3

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24 September 2017

N Dubois

4

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24 September 2017

P Netter

5

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24 September 2017

publication date

1 August 1993

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Clinical Pharmacokinetics

24 September 2017

published in

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24 September 2017

volume

25

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24 September 2017

issue

2

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24 September 2017

page(s)

115-123

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The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences

24 September 2017

cites work

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12 December 2020

Effect of racemic ibuprofen dose on the magnitude and duration of platelet cyclo-oxygenase inhibition: relationship between inhibition of thromboxane production and the plasma unbound concentration of S(+)-ibuprofen.

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12 December 2020

The pharmacokinetics of the enantiomers of flurbiprofen in patients with rheumatoid arthritis

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12 December 2020

Pharmacokinetic implications of stereoselective changes in plasma-protein binding: warfarin/sulfinpyrazone

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12 December 2020

The disposition of ketoprofen enantiomers in man

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12 December 2020

Pharmacokinetics of the R(-) and S(+) enantiomers of ibuprofen in the serum and synovial fluid of arthritis patients

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12 December 2020

Binding of pirprofen to human serum albumin studied by dialysis and spectroscopy techniques

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12 December 2020

Stereoselective disposition of ibuprofen enantiomers in man

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12 December 2020

Further characterization of specific drug binding sites on human serum albumin

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12 December 2020

Interaction of several coumarin compounds with human and canine plasma albumin

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12 December 2020

Pharmacokinetics of ketoprofen enantiomers in healthy subjects following single and multiple doses

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12 December 2020

Stereoselective binding of etodolac to human serum albumin

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12 December 2020

Difficulties in applying the Scatchard model of ligand binding to proteins--proposal of new mathematical tools--application to salicylates.

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12 December 2020

Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs

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12 December 2020

Protein binding of non-steroidal anti-inflammatory drugs in plasma and synovial fluid of arthritic patients

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12 December 2020

Determination of the (+)- and (-)-enantiomers of pirprofen in human plasma by high-performance liquid chromatography

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12 December 2020

Relationship of serum naproxen concentration to efficacy in rheumatoid arthritis

1 reference

12 December 2020

The contribution of enantiomers to variability in response to anti-inflammatory drugs

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12 December 2020

Enantioselective disposition of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs. I. 2-Phenylpropionic acid disposition.

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12 December 2020

Decrease of in vitro serum protein binding of salicylate in rheumatoid arthritis

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12 December 2020

Pharmacokinetics of the enantiomers of indoprofen in man

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12 December 2020

Enantioselective disposition of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs. II. 2-Phenylpropionic acid protein binding.

1 reference

12 December 2020

Pharmacokinetics of Ketoprofen Enantiomers in Young and Elderly Arthritic Patients following Single and Multiple Doses

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12 December 2020

Interaction of the Enantiomers of Warfarin with Human Serum Albumin, Peptides and Amino Acids

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12 December 2020

Drug-protein binding: recent advances in methodology: spectroscopic techniques

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12 December 2020

Stereoselective binding of the glucuronide conjugates of carprofen enantiomers to human serum albumin

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12 December 2020

Plasma protein binding of flurbiprofen: enantioselectivity and influence of pathophysiological status

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12 December 2020

Aspirin-like drugs may block pain independently of prostaglandin synthesis inhibition

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12 December 2020

Pharmacokinetics of Salicylate in Man

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12 December 2020

The metabolic chiral inversion of 2-phenylpropionic acid in rat, mouse and rabbit

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12 December 2020

The specific binding of L-tryptophan to serum albumin

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12 December 2020

Pharmacokinetics of S(+)- and R(-)-ibuprofen in volunteers and first clinical experience of S(+)-ibuprofen in rheumatoid arthritis.

1 reference

12 December 2020

Protein binding as a primary determinant of the clinical pharmacokinetic properties of non-steroidal anti-inflammatory drugs

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12 December 2020

Stereoselective disposition of etodolac enantiomers in synovial fluid

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12 December 2020

A circular dichroic investigation of the binding of fenoprofen, 2(3-phenoxyphenyl)-propionic acid, to human serum albumin

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12 December 2020

Enantioselective pharmacokinetics of etodolac in the rat: tissue distribution, tissue binding, and in vitro metabolism

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12 December 2020

Plasma protein binding of ketoprofen enantiomers in man: Method development and its application

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12 December 2020

[Binding of racemic indoprofen and its enantiomers to human serum albumin]

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12 December 2020

Pharmacological aspects of chiral nonsteroidal anti-inflammatory drugs

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12 December 2020

Stereoselective protein binding of ketoprofen: effect of albumin concentration and of the biological system

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12 December 2020

Stereoselective plasma protein binding of ibuprofen enantiomers

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12 December 2020

Stereoselective disposition of indoprofen in surgical patients

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12 December 2020

High-performance liquid chromatographic determination of stereoselective disposition of carprofen in humans

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12 December 2020

Resolution by affinity chromatography: stereoselective binding of racemic oxazepam esters to human serum albumin

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12 December 2020

Stereoselective pharmacokinetics of flurbiprofen in humans and rats

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12 December 2020

Etodolac: the chemistry, pharmacology, metabolic disposition, and clinical profile of a novel anti-inflammatory pyranocarboxylic acid

1 reference

12 December 2020

The pharmacokinetics of etodolac enantiomers in the rat. Lack of pharmacokinetic interaction between enantiomers.

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12 December 2020

Interaction of pirprofen enantiomers with human serum albumin

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12 December 2020

Application of a stereospecific high-performance liquid chromatography assay to a pharmacokinetic study of etodolac enantiomers in humans

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12 December 2020

Measurement of carprofen enantiomer concentrations in plasma and urine using L-leucinamide as the chiral coupling component

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12 December 2020

Direct determination of diastereomeric carprofen glucuronides in human plasma and urine and preliminary measurements of stereoselective metabolic and renal elimination after oral administration of carprofen in man.

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12 December 2020

10.2165/00003088-199325020-00004

Identifiers

DOI

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Dimensions Publication ID

24 September 2017

1048438624

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