(Q40862437)

24 September 2017

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression (English)

1 reference

24 September 2017

1 reference

2

1 reference

24 September 2017

3

1 reference

24 September 2017

Jack Bowden

1

1 reference

PMCID

4469799

24 September 2017

language of work or name

1 reference

1 April 2015

1 reference

International Journal of Epidemiology

24 September 2017

1 reference

24 September 2017

44

1 reference

24 September 2017

2

1 reference

24 September 2017

512-525

1 reference

Mendelian randomization studies: a review of the approaches used and the quality of reporting

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

The many weak instruments problem and Mendelian randomization

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Methodological challenges in mendelian randomization

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Calculating statistical power in Mendelian randomization studies.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Mendelian randomization analysis with multiple genetic variants using summarized data

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Use of Mendelian randomisation to assess potential benefit of clinical intervention

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Cohort profile: the 'children of the 90s'—the index offspring of the Avon Longitudinal Study of Parents and Children

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Avoiding bias from weak instruments in Mendelian randomization studies

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Hundreds of variants clustered in genomic loci and biological pathways affect human height

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Mendelian randomization in the era of genomewide association studies.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Modelling multiple sources of dissemination bias in meta-analysis

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Mendelian randomization as an instrumental variable approach to causal inference

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Using pseudo-data to correct for publication bias in meta-analysis

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Measuring inconsistency in meta-analyses

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Data dredging, bias, or confounding

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Funnel plots for detecting bias in meta-analysis: guidelines on choice of axis

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Bias in meta-analysis detected by a simple, graphical test

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Use of allele scores as instrumental variables for Mendelian randomization

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Power and sample size calculations for Mendelian randomization studies using one genetic instrument

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Random allocation in observational data: how small but robust effects could facilitate hypothesis-free causal inference

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Treatment-effect estimates adjusted for small-study effects via a limit meta-analysis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Explaining heterogeneity in meta-analysis: a comparison of methods.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469799

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYV080

The Fitting of Straight Lines if Both Variables are Subject to Error

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYV080

Two-Sample Instrumental Variables Estimators

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FIJE%2FDYV080

A robust P-value for treatment effect in meta-analysis with publication bias

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26050253

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/IJE/DYV080

1 reference

24 September 2017

1 reference

24 September 2017

1 reference

PMCID

4469799