(Q40865309)

24 September 2017

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title

Analysis of plasmid DNA from a pharmaceutical perspective (English)

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24 September 2017

Middaugh CR

1

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24 September 2017

Evans RK

series ordinal

2

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24 September 2017

Montgomery DL

series ordinal

3

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24 September 2017

Casimiro DR

series ordinal

4

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24 September 2017

language of work or name

English

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publication date

1 February 1998

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Journal of Pharmaceutical Sciences

24 September 2017

published in

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24 September 2017

volume

87

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24 September 2017

issue

2

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24 September 2017

page(s)

130-146

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The analysis of protein pharmaceuticals: near future advances

24 September 2017

cites work

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7 January 2021

DNA comes in many forms

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7 January 2021

Conformational and thermodynamic properties of supercoiled DNA.

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7 January 2021

Detection of proteins and phenol in DNA samples with second-derivative absorption spectroscopy

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7 January 2021

Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis

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7 January 2021

Comparison of ethidium bromide and 4'6-diamidino-2-phenylindole as quantitative fluorescent stains for DNA in agarose gels

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7 January 2021

A novel, sensitive fluorometric staining technique for the detection of DNA in RNA preparations

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7 January 2021

A comparison of resolution of DNA fragments between agarose gel and capillary zone electrophoresis in agarose solutions.

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7 January 2021

Separation of DNA restriction fragments by high performance capillary electrophoresis with low and zero crosslinked polyacrylamide using continuous and pulsed electric fields

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7 January 2021

Analysis of double-stranded DNA by capillary electrophoresis with laser-induced fluorescence detection using the monomeric dye SYBR green I.

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7 January 2021

Allelic discrimination by nick-translation PCR with fluorogenic probes

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7 January 2021

Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization

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7 January 2021

Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase

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7 January 2021

A strategy for rapid and efficient DNA sequencing by mass spectrometry

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7 January 2021

Ultrasensitive plasmid mapping by high performance capillary electrophoresis

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7 January 2021

Practical methods of mutation detection

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7 January 2021

Efficient detection of point mutations on color-coded strands of target DNA.

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7 January 2021

Screening for mutations by enzyme mismatch cleavage with T4 endonuclease VII.

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7 January 2021

Detection of 81 of 81 known mouse beta-globin promoter mutations with T4 endonuclease VII--the EMC method

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7 January 2021

Detection of mutations by cleavage of DNA heteroduplexes with bacteriophage resolvases

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7 January 2021

DNA chips: analysing sequence by hybridization to oligonucleotides on a large scale

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7 January 2021

The development of microfabricated arrays for DNA sequencing and analysis

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7 January 2021

An oligonucleotide hybridization approach to DNA sequencing

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7 January 2021

Analyzing and comparing nucleic acid sequences by hybridization to arrays of oligonucleotides: evaluation using experimental models

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7 January 2021

Biopolymer synthesis on polypropylene supports: oligonucleotide arrays

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7 January 2021

High-density oligonucleotide arrays

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7 January 2021

Multiplexed biochemical assays with biological chips

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7 January 2021

Light-generated oligonucleotide arrays for rapid DNA sequence analysis

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7 January 2021

Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis

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7 January 2021

Accessing genetic information with high-density DNA arrays.

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7 January 2021

To affinity ... and beyond!

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7 January 2021

Static and dynamic light scattering of biological macromolecules: what can we learn?

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7 January 2021

Analysis of Macromolecular Polydispersity in Intensity Correlation Spectroscopy: The Method of Cumulants

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7 January 2021

Dynamic light scattering for study of solution conformation and dynamics of superhelical DNA

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7 January 2021

Configurational and dynamic properties of different length superhelical DNAs measured by dynamic light scattering

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7 January 2021

Studies of DNA organization in hydrated spermidine-condensed DNA toruses and spermidine-DNA fibres

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7 January 2021

Direct observation of iron-induced conformational changes of mitochondrial DNA by high-resolution field-emission in-lens scanning electron microscopy

1 reference

7 January 2021

Superhelix dimensions of a 1868 base pair plasmid determined by scanning force microscopy in air and in aqueous solution.

1 reference

7 January 2021

Visualization of supercoiled DNA with atomic force microscopy in situ

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7 January 2021

High-resolution atomic-force microscopy of DNA: the pitch of the double helix

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7 January 2021

Collapse of single DNA molecule in poly(ethylene glycol) solutions

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7 January 2021

Observation and manipulation of different structural variants of individual cation-DNA complexes in the light microscope

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7 January 2021

Absorption and circular dichroism spectroscopy of nucleic acid duplexes and triplexes

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7 January 2021

Oligonucleotide interactions. III. Circular dichroism studies of the conformation of deoxyoligonucleolides

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7 January 2021

Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature

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7 January 2021

Different conformations of double-stranded nucleic acid in solution as revealed by circular dichroism

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7 January 2021

Circular dichroism spectra of oriented and unoriented deoxyribonucleic acid films—A preliminary study

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7 January 2021

Does DNA adopt the C form in concentrated salt solutions or in organic solvent water mixtures? An x-ray diffraction study of DNA fibers immersed in various media

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7 January 2021

Circular dichroism and DNA secondary structure

1 reference

7 January 2021

CD of the Li-salt of DNA in ethanol/water mixtures: evidence for the B- to C-form transition in solution

1 reference

7 January 2021

Conformation and circular dichroism of DNA

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7 January 2021

Energy-structure correlations of plasmid DNA in different topological forms

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7 January 2021

Changes in the c.d. spectra of calf thymus DNA induced by sequential polypeptides in aqueous solutions. Part I

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7 January 2021

Progression of human breast cancers to the metastatic state is linked to hydroxyl radical-induced DNA damage

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7 January 2021

The etiology and prediction of breast cancer. Fourier transform-infrared spectroscopy reveals progressive alterations in breast DNA leading to a cancer-like phenotype in a high proportion of normal women

1 reference

7 January 2021

Interaction of poly-L-lysine with nucleic acid. 3. An infrared and x-ray examination

1 reference

7 January 2021

DNA melting investigated by differential scanning calorimetry and Raman spectroscopy

1 reference

7 January 2021

Raman spectroscopy of DNA-metal complexes. II. The thermal denaturation of DNA in the presence of Sr2+, Ba2+, Mg2+, Ca2+, Mn2+, Co2+, Ni2+, and Cd2+.

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7 January 2021

Structure, interactions and dynamics of PRD1 virus I. Coupling of subunit folding and capsid assembly

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7 January 2021

Changes of phage T7 nucleoprotein structure at low ionic strength. A Raman spectroscopic study

1 reference

7 January 2021

Raman spectroscopy of the Ff gene V protein and complexes with poly(dA): nonspecific DNA recognition and binding

1 reference

7 January 2021

Sensitive fluorescence-based thermodynamic and kinetic measurements of DNA hybridization in solution

1 reference

7 January 2021

Evidence for the role of proteoglycans in cation-mediated gene transfer

1 reference

7 January 2021

Fluorescence studies of DNA and RNA structure and dynamics

1 reference

7 January 2021

Spectroscopic recognition of guanine dimeric hairpin quadruplexes by a carbocyanine dye.

1 reference

7 January 2021

A model for the T-antigen-induced structural alteration of the SV40 replication origin based upon experiments with specific probes for bent, straight, and unwound DNA.

1 reference

7 January 2021

A helicase assay based on the displacement of fluorescent, nucleic acid-binding ligands

1 reference

7 January 2021

Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.

1 reference

7 January 2021

Fluorescence energy transfer between two triple helix-forming oligonucleotides bound to duplex DNA.

1 reference

7 January 2021

Fluorescence energy transfer as a probe for nucleic acid structures and sequences.

1 reference

7 January 2021

Determination of DNA helical handedness by fluorescence resonance energy transfer

1 reference

7 January 2021

Instability and decay of the primary structure of DNA

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7 January 2021

Heat-induced depyrimidination of deoxyribonucleic acid in neutral solution

1 reference

7 January 2021

Mechanistic studies on depurination and apurinic site chain breakage in oligodeoxyribonucleotides

1 reference

7 January 2021

Elevated glucose 6-phosphate levels are associated with plasmid mutations in vivo

1 reference

7 January 2021

Modification of DNA by reducing sugars: a possible mechanism for nucleic acid aging and age-related dysfunction in gene expression

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7 January 2021

Estimation of apurinic/apyrimidinic sites and phosphotriesters in deoxyribonucleic acid treated with electrophilic carcinogens and mutagens.

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7 January 2021

Novel reagents for chemical cleavage at abasic sites and UV photoproducts in DNA

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7 January 2021

Synthesis and damage specificity of a novel probe for the detection of abasic sites in DNA

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7 January 2021

Superoxide accelerates DNA damage by elevating free-iron levels

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7 January 2021

DNA damage and oxygen radical toxicity

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7 January 2021

Repair of oxidative damage to DNA: enzymology and biology

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7 January 2021

Hydroxyl radical "footprinting": high-resolution information about DNA-protein contacts and application to lambda repressor and Cro protein

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7 January 2021

LXXIII.—Oxidation of tartaric acid in presence of iron

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7 January 2021

In the absence of catalytic metals ascorbate does not autoxidize at pH 7: ascorbate as a test for catalytic metals.

1 reference

7 January 2021

Iron-mediated DNA damage: sensitive detection of DNA strand breakage catalyzed by iron

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7 January 2021

Differential dependence on chromatin structure for copper and iron ion induction of DNA double-strand breaks

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7 January 2021

The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate

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7 January 2021

Rate of depurination of native deoxyribonucleic acid

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7 January 2021

Rate of chain breakage at apurinic sites in double-stranded deoxyribonucleic acid

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7 January 2021

In vivo detection of radical adducts by electron spin resonance

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7 January 2021

DNA strand cleavage as a sensitive assay for the production of hydroxyl radicals by microsomes: role of cytochrome P4502E1 in the increased activity after ethanol treatment

1 reference

7 January 2021

Three chemically distinct types of oxidants formed by iron-mediated Fenton reactions in the presence of DNA.

1 reference

7 January 2021

Quantitation of the hydroxyl radical adducts of salicylic acid by micellar electrokinetic capillary chromatography: oxidizing species formed by a Fenton reaction

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7 January 2021

Quantification of radiation-induced hydroxyl radicals within nucleohistones using a molecular fluorescent probe

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7 January 2021

Chemical changes induced in DNA by ionizing radiation.

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7 January 2021

Yields of radiation-induced base products in DNA: effects of DNA conformation and gassing conditions.

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7 January 2021

Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection

1 reference

7 January 2021

Assessment of DNA oxidative damage by quantification of thymidine glycol residues using gas chromatography/electron capture negative ionization mass spectrometry.

1 reference

7 January 2021

Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells

1 reference

7 January 2021

8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity

1 reference

7 January 2021

DNA deoxyribophosphodiesterase and an activity that cleaves DNA containing thymine glycol adducts in Deinococcus radiodurans.

1 reference

7 January 2021

Use of repair endonucleases to characterize DNA damage induced by reactive oxygen species in cellular and cell-free systems.

1 reference

7 January 2021

A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy

1 reference

7 January 2021

Heat-induced deamination of cytosine residues in deoxyribonucleic acid

1 reference

7 January 2021

Bisulfite induces tandem double CC-->TT mutations in double-stranded DNA. 2. Kinetics of cytosine deamination.

1 reference

7 January 2021

Analysis of uracil in DNA by gas chromatography-mass spectrometry

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7 January 2021

Direct gene transfer into muscle

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7 January 2021

Protection of chickens from Newcastle disease by vaccination with a linear plasmid DNA expressing the F protein of Newcastle disease virus

1 reference

7 January 2021

The generation of DNA single-strand breaks during the reduction of chromate by ascorbic acid and/or glutathione in vitro

1 reference

7 January 2021

Iron(III) binding in DNA solutions: Complex formation and catalytic activity in the oxidation of hydrazine derivatives

1 reference

7 January 2021

Sequence from spectrometry: a realistic prospect?

1 reference

7 January 2021

Qualitative and quantitative measurements of oligonucleotides in gene therapy: Part I. In vitro models.

1 reference

7 January 2021

Qualitative and quantitative measurements of oligonucleotides in gene therapy: Part II in vivo models

1 reference

7 January 2021

Size and conformational stability of the hepatitis A virus used to prepare VAQTA, a highly purified inactivated vaccine

1 reference

7 January 2021

Identifiers

DOI

10.1021/JS970367A

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24 September 2017

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