(Q41841707)

English

DNA strand cleavage as a sensitive assay for the production of hydroxyl radicals by microsomes: role of cytochrome P4502E1 in the increased activity after ethanol treatment

scientific article published on September 1994

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

DNA strand cleavage as a sensitive assay for the production of hydroxyl radicals by microsomes: role of cytochrome P4502E1 in the increased activity after ethanol treatment (English)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

author name string

E Kukielka

1

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

A I Cederbaum

2

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

language of work or name

0 references

publication date

1 September 1994

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

302 ( Pt 3)

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

773-779

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

The feeding of alcohol in liquid diets: two decades of applications and 1982 update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Iron species of hepatic microsomes from control and phenobarbital-treated rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

The importance of free radicals and catalytic metal ions in human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Characterization and identification of a pyrazole-inducible form of cytochrome P-450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Hydroxyl-radical production and ethanol oxidation by liver microsomes isolated from ethanol-treated rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Role of metals in oxygen radical reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Thiol-dependent DNA damage produced by anthracycline-iron complexes. The structure-activity relationships and molecular mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Ascorbate/iron mediation of hydroxyl free radical damage to PBR322 plasmid DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Iron-dependent hydroxyl radical formation and DNA damage from a novel metabolite of the clinically active antitumor drug VP-16.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Characterization of hydroxyl free radical mediated damage to plasmid pBR322 DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Role of ethanol-inducible cytochrome P450 (P450IIE1) in catalysing the free radical activation of aliphatic alcohols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137298

6 June 2018

Single-strand scissions induced in circular and linear lambda DNA by the presence of dithiothreitol and other reducing agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic effects of ethanol in perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced nicotinamide-adenine dinucleotide phosphate oxidase: activity enhanced by ethanol consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of hepatic microsomal reduced nicotinamide adenine dinucleotide phosphate-dependent production of hydrogen peroxide by chronic prior treatment with ethanol

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA strand scission by enzymically generated oxygen radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione-dependent protection by rat liver microsomal protein against lipid peroxidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased chemiluminescence and superoxide production in the liver of chronically ethanol-treated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of iron chelates in hydroxyl radical production by rat liver microsomes, NADPH-cytochrome P-450 reductase and xanthine oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the ability of ferric complexes to catalyze microsomal chemiluminescence, lipid peroxidation, and hydroxyl radical generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased NADPH-dependent chemiluminescence by microsomes after chronic ethanol consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxyl radical generation and DNA strand scission mediated by natural anticancer and synthetic quinones

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P-450 (P-450IIE1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron ion-dependent modification of bases in DNA by the superoxide radical-generating system hypoxanthine/xanthine oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

tert-butyl hydroperoxide-dependent microsomal release of iron and lipid peroxidation. I. Evidence for the reductive release of nonheme, nonferritin iron

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADH-dependent microsomal interaction with ferric complexes and production of reactive oxygen intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evaluation of the antioxidant and potential pro-oxidant properties of food additives and of trolox C, vitamin E and probucol

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased NADH-dependent production of reactive oxygen intermediates by microsomes after chronic ethanol consumption: Comparisons with NADPH

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased NADPH- and NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of chronic ethanol consumption on microsomal lipid peroxidation. Role of iron and comparison between controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Iminodaunomycin. An anthracycline with unique properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydroxyl radical generation by microsomes after chronic ethanol consumption

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of ethanol on the metabolic activities of the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/7945202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3020773

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 October 2017

ResearchGate publication ID

0 references

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