(Q40867073)

English

Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin.

scientific article published on November 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906131%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906131%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

inferred from title

4

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8 November 2019

author name string

Hinoi T

1

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8 November 2019

Yamamoto H

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906131%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Kishida M

3

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8 November 2019

Kishida S

5

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8 November 2019

Kikuchi A

6

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8 November 2019

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publication date

1 November 2000

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8 November 2019

Journal of Biological Chemistry

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8 November 2019

275

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8 November 2019

44

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8 November 2019

34399-34406

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8 November 2019

Association of the APC gene product with beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Association of the APC tumor suppressor protein with catenins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Wnt signaling: a common theme in animal development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Signal transduction by the Wnt family of ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Functional interaction of beta-catenin with the transcription factor LEF-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Roles of Axin in the Wnt signalling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Modulation of Wnt signaling by Axin and Axil

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

beta-catenin is a target for the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Axin prevents Wnt-3a-induced accumulation of beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Cytoskeletal reorganization by soluble Wnt-3a protein signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Regulation of interaction of ras p21 with RalGDS and Raf-1 by cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with Axin and beta-catenin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Negative regulation of Wingless signaling by D-axin, a Drosophila homolog of axin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Axin directly interacts with plakoglobin and regulates its stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

The oncogenic activation of beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Interaction of dishevelled and Xenopus axin-related protein is required for wnt signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

The dishevelled protein is modified by wingless signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Accumulation of Armadillo induced by Wingless, Dishevelled, and dominant-negative Zeste-White 3 leads to elevated DE-cadherin in Drosophila clone 8 wing disc cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003997200

21 January 2018

Identifiers

10.1074/JBC.M003997200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906131%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906131%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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