(Q40867771)

24 September 2017

1 reference

title

Protein tyrosine kinase growth factor receptors and their ligands in development, differentiation, and cancer (English)

1 reference

24 September 2017

Wilks AF

1

1 reference

24 September 2017

publication date

1 January 1993

1 reference

Advances in Cancer Research

24 September 2017

published in

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24 September 2017

volume

60

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24 September 2017

page(s)

43-73

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Growth factors and cancer

24 September 2017

cites work

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7 January 2021

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

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7 January 2021

The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily

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7 January 2021

Effect on eye development of dominant mutations in Drosophila homologue of the EGF receptor.

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7 January 2021

The neu oncogene encodes an epidermal growth factor receptor-related protein

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7 January 2021

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

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7 January 2021

Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye.

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7 January 2021

Redox regulation of a protein tyrosine kinase in the endoplasmic reticulum

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7 January 2021

A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family

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7 January 2021

Characterization of an activated human ros gene

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7 January 2021

Characterization of ROS1 cDNA from a human glioblastoma cell line

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7 January 2021

Molecular themes in oncogenesis

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7 January 2021

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

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7 January 2021

Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster

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7 January 2021

Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains

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7 January 2021

"Replacement" of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential

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7 January 2021

cell clones and pattern formation: Studies onsevenless, a mutant ofDrosophila melanogaster

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7 January 2021

Oncogenes and signal transduction

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7 January 2021

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor

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7 January 2021

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

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7 January 2021

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

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7 January 2021

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3.

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7 January 2021

Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus

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7 January 2021

Growth factors in development, transformation, and tumorigenesis

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7 January 2021

McDonough feline sarcoma virus: characterization of the molecularly cloned provirus and its feline oncogene (v-fms)

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Migratory and postmigratory mouse primordial germ cells behave differently in culture

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

New Human Transforming Genes Detected by a Tumorigenicity Assay

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Deletion of the c-kit protooncogene in the human developmental defect piebald trait

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Cell lineage of the imaginal discs inDrosophila gynandromorphs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

A new technique for the assay of infectivity of human adenovirus 5 DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Nucleotide sequences of feline retroviral oncogenes (v-fes) provide evidence for a family of tyrosine-specific protein kinase genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Genetic dissection of the photoreceptor system in the compound eye of Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Induction of cell fate in the Drosophila retina: the bride of sevenless protein is predicted to contain a large extracellular domain and seven transmembrane segments

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

K-sam, an amplified gene in stomach cancer, is a member of the heparin-binding growth factor receptor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Functional inactivation of genes by dominant negative mutations

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

A novel putative tyrosine kinase receptor encoded by the eph gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Molecular cloning of the neu gene: absence of gross structural alteration in oncogenic alleles

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Cooperation between oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Gene amplification and overexpression of EGF receptor in squamous cell carcinomas of the head and neck

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Expression during Drosophila development of DER, a gene related to erbB-1 and neu: Correlations with mutant phenotypes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The trk proto-oncogene encodes a receptor for nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Transforming activity of human tumor DNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Report of the committee on comparative mapping

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Characterization of elk, a brain-specific receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

47 Isolation of cDNA clones that encode active protein-tyrosine kinases using antibodies against phosphotyrosine

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The Drosophila EGF receptor gene homolog: conservation of both hormone binding and kinase domains

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Direct interaction of a ligand for the erbB2 oncogene product with the EGF receptor and p185erbB2.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Primary structure and functional expression of rat and human stem cell factor DNAs

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Molecular and biochemical characterization of the human trk proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Gene-induced embryological modifications of primordial germ cells in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Three different human tumor cell lines contain different oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Regulation of the fibroblast growth factor receptor in early Xenopus embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Isolation of an amplified DNA sequence in stomach cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Nucleotide sequence of avian sarcoma virus UR2 and comparison of its transforming gene with other members of the tyrosine protein kinase oncogene family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Mutations affecting segment number and polarity in Drosophila

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7 January 2021

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster : I. Zygotic loci on the second chromosome

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7 January 2021

axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Frequent generation of oncogenes by in vitro recombination of TRK protooncogene sequences

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https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

A distinctive family of embryonic protein-tyrosine kinase receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Human-tumor-derived cell lines contain common and different transforming genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Molecular basis of the activation of the tumorigenic potential of Gag-insulin receptor chimeras

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The maternal ventralizing locus torpedo is allelic to faint little ball, an embryonic lethal, and encodes the Drosophila EGF receptor homolog.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Development of the Drosophila retina, a neurocrystalline lattice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Expression of the c-fms proto-oncogene and of the cytokine, CSF-1, during mouse embryogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Two forms of the basic fibroblast growth factor receptor-like mRNA are expressed in the developing mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Cell-cell interaction in the Drosophila retina: the bride of sevenless gene is required in photoreceptor cell R8 for R7 cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The neu gene: an erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The Drosophila EGF receptor homolog (DER) gene is allelic to faint little ball, a locus essential for embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Germ line and soma cooperate during oogenesis to establish the dorsoventral pattern of egg shell and embryo in Drosophila melanogaster

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Structure and activity of the sevenless protein: a protein tyrosine kinase receptor required for photoreceptor development in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The v-sea oncogene of avian erythroblastosis retrovirus S13: another member of the protein-tyrosine kinase gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The Drosophila gene torso encodes a putative receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Zygotic genes that mediate torso receptor tyrosine kinase functions in the Drosophila melanogaster embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

ret transforming gene encodes a fusion protein homologous to tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Activation of a novel human transforming gene, ret, by DNA rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

The Dominant W 42 Spotting Phenotype Results from a Missense Mutation in the c- kit Receptor Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Sevenless: a cell-specific homeotic mutation of the Drosophila eye

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Cloning members of protein-tyrosine kinase family using polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Identification of a ligand for the c-kit proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Growth factor receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Oncogenic activation of the human trk proto-oncogene by recombination with the ribosomal large subunit protein L7a

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver--conditioned medium.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2808%2960822-2

7 January 2021

10.1016/S0065-230X(08)60822-2

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