(Q40874638)

English

The tyrosine kinase PYK-2/RAFTK regulates natural killer (NK) cell cytotoxic response, and is translocated and activated upon specific target cell recognition and killing

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

The tyrosine kinase PYK-2/RAFTK regulates natural killer (NK) cell cytotoxic response, and is translocated and activated upon specific target cell recognition and killing (English)

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

0 references

Francisco Sánchez-Madrid

9

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

object named as

D Sancho

1

0 references

Miguel López-Botet

object named as

M López-Botet

8

0 references

object named as

M Nieto

2

0 references

author name string

M Llano

3

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

J L Rodríguez-Fernández

4

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

R Tejedor

5

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

S Avraham

6

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

C Cabañas

7

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

language of work or name

0 references

publication date

1 June 2000

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

Journal of Cell Biology

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

149

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

1249-1262

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

Negative regulation of PYK2/related adhesion focal tyrosine kinase signal transduction by hematopoietic tyrosine phosphatase SHPTP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Natural killer cell activation and inhibition by receptors for MHC class I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Regulation of immune responses through inhibitory receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Signaling through focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Cytoskeletal rearrangement during migration and activation of T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Identification of a new Pyk2 target protein with Arf-GAP activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Stable association of PYK2 and p130(Cas) in osteoclasts and their co-localization in the sealing zone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Roles of chemokines and receptor polarization in NK-target cell interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Association of DAP12 with activating CD94/NKG2C NK cell receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Signaling through scaffold, anchoring, and adaptor proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Functional role for Syk tyrosine kinase in natural killer cell-mediated natural cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Selective modulation of protein kinase C-theta during T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Localization of protein kinases by anchoring proteins: a theme in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Angiotensin II activates at least two tyrosine kinases in rat liver epithelial cells. Separation of the major calcium-regulated tyrosine kinase from p125FAK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

A heparin-binding protein involved in inhibition of smooth-muscle cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Cell biology of cytotoxic and helper T cell functions: immunofluorescence microscopic studies of single cells and cell couples

1 reference

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24 September 2017

Gamma-tubulin is present in Drosophila melanogaster and Homo sapiens and is associated with the centrosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

γ-Tubulin is a highly conserved component of the centrosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

24 September 2017

Specific engagement of the CD94/NKG2-A killer inhibitory receptor by the HLA-E class Ib molecule induces SHP-1 phosphatase recruitment to tyrosine-phosphorylated NKG2-A: evidence for receptor function in heterologous transfectants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

More on target with protein phosphorylation: conferring specificity by location

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

T cell receptor engagement induces tyrosine phosphorylation of FAK and Pyk2 and their association with Lck.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

Characterization of RAFTK, a novel focal adhesion kinase, and its integrin-dependent phosphorylation and activation in megakaryocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

Characterization of a cell line, NKL, derived from an aggressive human natural killer cell leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

Functional ambivalence of the Kp43 (CD94) NK cell-associated surface antigen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

25 September 2017

Leukocyte polarization in cell migration and immune interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

Membrane compartmentation is required for efficient T cell activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

HLA class I specific inhibitory receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

Signal transduction during natural killer cell activation: inside the mind of a killer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

Immunoreceptor tyrosine-based inhibition motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

Migratory functions of natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

Fc receptor biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

A novel functional cell surface dimer (Kp43) expressed by natural killer cells and T cell receptor-gamma/delta+ T lymphocytes. I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

15 June 2018

Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase, to 8p11.2-p22 by nonisotopic in situ hybridization

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

NK cell receptors

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

Natural killer cell receptors

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

The CD94 and NKG2-A C-type lectins covalently assemble to form a natural killer cell inhibitory receptor for HLA class I molecules

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

From TCR Engagement to T Cell Activation

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

The Actin Cytoskeleton and Lymphocyte Activation

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

Costimulation: building an immunological synapse

2 references

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2175114

2 December 2018

Selection of recombinant vaccinia viruses on the basis of plaque formation

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

Focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

The activating form of CD94 receptor complex: CD94 covalently associated with the Kp39 protein that represents the product of the NKG2-C gene

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

Cytotoxic T lymphocytes express a beta3 integrin which can induce the phosphorylation of focal adhesion kinase and the related PYK-2

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

T lymphocyte costimulation mediated by reorganization of membrane microdomains

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

https://api.crossref.org/works/10.1083%2FJCB.149.6.1249

21 January 2018

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn

1 reference

https://pubmed.ncbi.nlm.nih.gov/10851022

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proline-rich tyrosine kinase-2 activation by beta 1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10851022

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microtubule retraction into the uropod and its role in T cell polarization and motility

1 reference

https://pubmed.ncbi.nlm.nih.gov/10851022

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1083/JCB.149.6.1249

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

ResearchGate publication ID

0 references

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