(Q40876187)

24 September 2017

title

The expression and regulation of drug metabolism in human placenta (English)

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24 September 2017

Pasanen M

1

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24 September 2017

language of work or name

English

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publication date

1 June 1999

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Advanced Drug Delivery Reviews

24 September 2017

published in

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24 September 2017

volume

38

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24 September 2017

issue

1

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24 September 2017

page(s)

81-97

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Placental drug transfer: Effects of gestational age and species

24 September 2017

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Cigarette smoking: stimulatory effect on metabolism of 3,4-benzpyrene by enzymes in human placenta

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Intrahepatic cholestasis of pregnancy impairs the activities of human placental xenobiotic and steroid metabolizing enzymes in vitro

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7 January 2021

The expression and environmental regulation of P450 enzymes in human placenta

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7 January 2021

Immunochemical and molecular biological studies on human placental cigarette smoke-inducible cytochrome P-450-dependent monooxygenase activities

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7 January 2021

Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells

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Genetic and environmental regulation of aryl hydrocarbon hydroxylase in man: studies with liver, lung, placenta, and lymphocytes.

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7 January 2021

Differential inhibition of human placental monooxygenase activity: evidence for multiple forms of 7-ethoxycoumarin O-deethylase

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7 January 2021

Human placental hydroxylation of 3,4-benzpyrene during early gestation and at term.

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7 January 2021

3,4‐Benzpyrene and N‐Methylaniline Metabolizing Enzymes in the Immature Human Foetus and Placenta*

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7 January 2021

Population distribution of placental benzo(α)pyrene metabolism in smokers

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7 January 2021

Effect of maternal cigarette smoking on 3,4-benzpyrene and N-methylaniline metabolism in human fetal liver and placenta

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7 January 2021

The effect of cigarette smoking on 7-ethoxyresorufin O-deethylase and other monooxygenase activities in human liver: analyses with monoclonal antibodies

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7 January 2021

Enzyme activities in the term human placenta: in vitro effect of cadmium

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7 January 2021

Comparative studies on the oxidation and reduction of drug substrates in human placental versus rat hepatic microsomes

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7 January 2021

Freezing affects the activity and subcellular distribution profile of human placental xenobiotic- and steroid-metabolizing enzymes

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7 January 2021

Comparison of the O-dealkylation of 7-ethoxycoumarin and the hydroxylation of benzo(a)pyrene in human placenta. Effect of cigarette smoking

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7 January 2021

Inhibition of human hepatic and placental xenobiotic monooxygenases by imidazole antimycotics

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7 January 2021

Phenotyping of cytochromes P-450 in human tissues with monoclonal antibodies

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7 January 2021

Immunohistochemical detection of human placental cytochrome P-450-associated mono-oxygenase system inducible by maternal cigarette smoking

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7 January 2021

The murine Ah locus: in utero toxicity and teratogenesis associated with genetic differences in benzo[a]pyrene metabolism

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7 January 2021

Identification of microsomal, organic hydroperoxide-dependent catechol estrogen formation: comparison with NADPH-dependent mechanism

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7 January 2021

ARNT-deficient mice and placental differentiation

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7 January 2021

Differential expression and regulation of members of the cytochrome P450IA gene subfamily in human tissues

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7 January 2021

Analysis of the biotransformation of benzo[a]pyrene in human fetal and placental tissues with high-pressure liquid chromatography

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7 January 2021

Stereoselective and regioselective hydroxylation of warfarin and selective O-dealkylation of phenoxazone ethers in human placenta

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7 January 2021

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.

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7 January 2021

Properties of an endogenous arachidonic acid--elicited relaxing mechanism in human placental vessels

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7 January 2021

Cytochrome P450 metabolites of arachidonic acid in human placenta

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7 January 2021

The constitutive 7-ethoxycoumarin O-deethylase activity of human placental microsomes: relationship to aromatase

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7 January 2021

Metabolic activation of aflatoxin B1 by human placental microsomes

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7 January 2021

Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples

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7 January 2021

Pharmacokinetics of oxcarbazepine and carbamazepine in human placenta

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7 January 2021

Stabilization of cytochrome P450j messenger ribonucleic acid in the diabetic rat

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7 January 2021

Cytochrome P450IIE1 is elevated in lymphocytes from poorly controlled insulin-dependent diabetics

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7 January 2021

Acetaldehyde production and transfer by the perfused human placental cotyledon.

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7 January 2021

Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?

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7 January 2021

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature

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7 January 2021

Human cytochromes P450: problems and prospects

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7 January 2021

P450 enzymes. Inhibition mechanisms, genetic regulation and effects of liver disease

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7 January 2021

The human hepatic cytochromes P450 involved in drug metabolism

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7 January 2021

Significance of cytochrome P-450 (P-450 HFLa) of human fetal livers in the steroid and drug oxidations

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7 January 2021

The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver.

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7 January 2021

Cytochrome P450 isoforms in human fetal tissues related to phenobarbital-inducible forms in the mouse

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7 January 2021

Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta

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7 January 2021

Quantitation of mRNAs specific for the mixed-function oxidase system in rat liver and extrahepatic tissues during development

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7 January 2021

Function of P-glycoprotein expressed in placenta and mole

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7 January 2021

Purification and immunological characterization of human placental mitochondrial cytochrome P-450

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7 January 2021

Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta

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7 January 2021

Purification to homogeneity of aromatase from human placenta

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7 January 2021

Isolation and characterization of a complementary DNA specific for human aromatase-system cytochrome P-450 mRNA.

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7 January 2021

Regulation of human aromatase cytochrome P450 gene expression.

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7 January 2021

Cytochromes P450 11: expression of the CYP19 (aromatase) gene: an unusual case of alternative promoter usage.

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7 January 2021

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

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7 January 2021

Metabolism of cocaine by human placentas: implications for fetal exposure

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7 January 2021

Aromatization of Androstenedione by Microsomes from the Human Placenta after Gestational Alcohol Consumption

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7 January 2021

The effects of an interferon inducer, polyriboinosinic polyribocytidylic acid on cytochrome P-450 dependent hepatic progesterone metabolism

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7 January 2021

Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism

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7 January 2021

Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome P450 and carcinogen metabolism in male hamster liver

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7 January 2021

Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice

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7 January 2021

Quinone reductase activity in the first trimester placenta: effect of cigarette smoking and polycyclic aromatic hydrocarbons

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7 January 2021

Human placental cytochrome P450 and quinone reductase enzyme induction in relation to maternal smoking

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7 January 2021

In vitro effect of mercury on aryl hydrocarbon hydroxylase, quinone reductase, catecholamine-O-methyltransferase and glucose-6-phosphate dehydrogenase activities in term human placenta.

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7 January 2021

Expression of nitric oxide synthase by syncytiotrophoblast in human placental villi

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7 January 2021

Control of the ductus arteriosus--a new function for cytochrome P450, endothelin and nitric oxide

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7 January 2021

Pre-eclampsia-like conditions produced by nitric oxide inhibition: effects of L-arginine, D-arginine and steroid hormones.

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7 January 2021

Regiospecificity of placental metabolism by cytochromes P450 and glutathione S-transferase

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7 January 2021

Inhibition of human term placental and fetal liver glutathione-S-transferases by fatty acids and fatty acid esters

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7 January 2021

Glutathione peroxidase, glutathione reductase, glutathione S-transferase, and γ-glutamyltranspeptidase activities in the human early pregnancy placenta

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https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900008-3

7 January 2021

Epoxide hydrolase in human placenta at different stages of pregnancy

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https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900008-3

7 January 2021

Augmentation of polynuclear aromatic hydrocarbon metabolism of human placental tissues of first-trimester pregnancy by cigarette smoke exposure

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https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900008-3

7 January 2021

Inactivation of human placenta glutathione S-transferase by SH/SS exchange reaction with biological disulfides

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https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900008-3

7 January 2021

Glutathione S-transferases: gene structure and regulation of expression

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7 January 2021

Glutathione status of placentae from differently polluted regions of Ukraine.

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7 January 2021

Identification of a novel human glutathione S-transferase using bioinformatics

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7 January 2021

Antiepileptic drug therapy and reproductive consequences: functional and morphologic effects

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7 January 2021

Nomenclature for N-acetyltransferases

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7 January 2021

Solubilization and partial purification of human placental cytochromes P-450

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7 January 2021

Interactions of steroids with human placental cytochrome P-450 in the presence of carbon monoxide

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https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900008-3

7 January 2021

Differential inhibition of androst-4-en-3,17-dione aromatization by carbon monoxide in the presence of estr-4-en-3,17-dione

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7 January 2021

Interactions of endogenous and exogenous estrogenic compounds with human placental microsomal cytochrome P-450 (P-450hpm)

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https://api.crossref.org/works/10.1016%2FS0169-409X%2899%2900008-3

7 January 2021

Interaction of drugs and steroids with human placental microsomes

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7 January 2021

10.1016/S0169-409X(99)00008-3

Identifiers

DOI

1 reference

24 September 2017

1 reference