(Q40878082)

24 September 2017

title

Constitutive activation of STAT5 by a point mutation in the SH2 domain (English)

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24 September 2017

Ariyoshi K

1

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24 September 2017

Nosaka T

2

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24 September 2017

Yamada K

3

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24 September 2017

Onishi M

4

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24 September 2017

Oka Y

5

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24 September 2017

Miyajima A

6

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24 September 2017

Kitamura T

7

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24 September 2017

language of work or name

English

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publication date

1 August 2000

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

275

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24 September 2017

issue

32

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24 September 2017

page(s)

24407-24413

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STATs: signal transducers and activators of transcription

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet?

21 January 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

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STATs and gene regulation

21 January 2018

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B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.

21 January 2018

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Stat5a is mandatory for adult mammary gland development and lactogenesis.

21 January 2018

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Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

21 January 2018

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

21 January 2018

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

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Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

21 January 2018

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STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells

21 January 2018

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Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909771199

Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909771199

Efficient screening of retroviral cDNA expression libraries

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909771199

Efficient retroviral-mediated gene transfer into human B lymphoblastoid cells expressing mouse ecotropic viral receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909771199

The primary structure of the putative oncogene pim-1 shows extensive homology with protein kinases.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909771199

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909771199

A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Structure and function of a new STAT-induced STAT inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

A family of cytokine-inducible inhibitors of signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909771199

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Three-dimensional structure of the Stat3beta homodimer bound to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Mutations in src homology regions 2 and 3 of activated chicken c-src that result in preferential transformation of mouse or chicken cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M909771199

Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Bcl-X is the major pleiotropic anti-apoptotic gene activated by retroviral insertion mutagenesis in an IL-3 dependent bone marrow derived cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Jak-STAT signaling induced by the v-abl oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Signalling by the oncogenic receptor tyrosine kinase Xmrk leads to activation of STAT5 in Xiphophorus melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

Three-dimensional solution structure of the src homology 2 domain of c-abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M909771199

21 January 2018

Identifiers

DOI

10.1074/JBC.M909771199

1 reference

24 September 2017

1 reference