(Q40880066)

English

Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes

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scholarly article

1 reference

Europe PubMed Central

24 September 2017

Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes (English)

1 reference

Europe PubMed Central

24 September 2017

Diego Luis Medina

1

1 reference

Europe PubMed Central

24 September 2017

Pilar Santisteban

3

1 reference

Europe PubMed Central

24 September 2017

author name string

M J Toro

2

1 reference

Europe PubMed Central

24 September 2017

language of work or name

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publication date

1 May 2000

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Europe PubMed Central

24 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

24 September 2017

275

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Europe PubMed Central

24 September 2017

20

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Europe PubMed Central

24 September 2017

15549-15556

1 reference

Europe PubMed Central

24 September 2017

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CDK inhibitors: positive and negative regulators of G1-phase progression

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Principles of CDK regulation

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

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Somatostatin is expressed in FRTL-5 thyroid cells and prevents thyrotropin-mediated down-regulation of the cyclin-dependent kinase inhibitor p27kip1.

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Control of c-fos and c-myc proto-oncogene induction in rat thyroid cells in culture

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TGF-beta1 actions on FRTL-5 cells provide a model for the physiological regulation of thyroid growth.

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21 January 2018

Thyrotropin induces G1 cyclin expression and accelerates G1 phase after insulin-like growth factor I stimulation in FRTL-5 cells

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21 January 2018

Somatostatin inhibits deoxyribonucleic acid synthesis induced by both thyrotropin and insulin-like growth factor-I in FRTL5 cells

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Somatostatin inhibits PC Cl3 thyroid cell proliferation through the modulation of phosphotyrosine activity. Impairment of the somatostatinergic effects by stable expression of E1A viral oncogene

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21 January 2018

A cell cycle-regulated inhibitor of cyclin-dependent kinases

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21 January 2018

Translational control of p27Kip1 accumulation during the cell cycle

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Mevalonate dependency of the early cell cycle mitogenic response to epidermal growth factor and prostaglandin F2 alpha in Swiss mouse 3T3 cells

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An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

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Rho GTPases and signaling networks

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p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

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Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

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Culture of hormone-dependent functional epithelial cells from rat thyroids

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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21 January 2018

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

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The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway

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21 January 2018

cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha

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21 January 2018

Calcium phosphate-mediated transfection of primary cultured brain neurons using GFP expression as a marker: application for single neuron electrophysiology.

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A Detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis

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21 January 2018

Mechanism of action of somatostatin

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21 January 2018

Function of the homeo and paired domain proteins TTF-1 and Pax-8 in thyroid cell proliferation

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21 January 2018

Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.

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21 January 2018

Regulation of protein kinase C isoforms in FRTL-5 thyroid cells by TSH and phorbol ester

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21 January 2018

Differential effects of protein kinase A on Ras effector pathways

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21 January 2018

Insulin and TSH promote growth in size of PC Cl3 rat thyroid cells, possibly via a pathway different from DNA synthesis: comparison with FRTL-5 cells

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21 January 2018

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

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21 January 2018

Transfected human somatostatin receptor type 2, SSTR2, not only inhibits adenylate cyclase but also stimulates phospholipase C and Ca2+ mobilization

1 reference

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21 January 2018

Co-purification of a protein tyrosine phosphatase with activated somatostatin receptors from rat pancreatic acinar membranes

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21 January 2018

Insulin-like growth factor-I stimulates the growth of rat thyroid cells in culture and synergizes the stimulation of DNA synthesis induced by TSH and Graves'-IgG

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21 January 2018

Adenosine 3',5'-monophosphate mediates both the mitogenic effect of thyrotropin and its ability to amplify the response to insulin-like growth factor I in FRTL5 cells

1 reference

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sst2 somatostatin receptor mediates cell cycle arrest and induction of p27(Kip1). Evidence for the role of SHP-1

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21 January 2018

Evidence that adenosine 3',5'-monophosphate mediates stimulation of thyroid growth in FRTL5 cells

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21 January 2018

Identifiers

10.1074/JBC.275.20.15549

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

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