(Q40881293)

24 September 2017

title

Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha (English)

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24 September 2017

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M P Pando

1

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24 September 2017

I M Verma

series ordinal

2

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24 September 2017

language of work or name

English

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publication date

1 July 2000

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

275

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24 September 2017

issue

28

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24 September 2017

page(s)

21278-21286

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NF-kappa B: ten years after

24 September 2017

cites work

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

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N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

21 January 2018

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21 January 2018

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21 January 2018

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Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

21 January 2018

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Constitutive phosphorylation of I kappa B alpha by casein kinase II

21 January 2018

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Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha

21 January 2018

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21 January 2018

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21 January 2018

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IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

21 January 2018

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21 January 2018

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c-rel activates but v-rel suppresses transcription from kappa B sites

21 January 2018

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Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required

21 January 2018

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Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

21 January 2018

1 reference

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Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

21 January 2018

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Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation

21 January 2018

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The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

21 January 2018

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M002532200

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M002532200

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

21 January 2018

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A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M002532200

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24 September 2017

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