(Q40888981)

English

Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

Chen RH

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Ding WV

2

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

McCormick F

3

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

language of work or name

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publication date

1 June 2000

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Europe PubMed Central

PubMed publication ID

24 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

24 September 2017

275

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

17894-17899

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

1 reference

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Cell adhesion: the molecular basis of tissue architecture and morphogenesis

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21 January 2018

The oncogenic activation of beta-catenin

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Regulation of LEF-1/TCF transcription factors by Wnt and other signals

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21 January 2018

Wnt signaling: a common theme in animal development

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Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

1 reference

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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

1 reference

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21 January 2018

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

1 reference

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

1 reference

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21 January 2018

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M905336199

21 January 2018

Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

1 reference

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Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

1 reference

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21 January 2018

Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level

1 reference

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21 January 2018

beta-catenin is a target for the ubiquitin-proteasome pathway

1 reference

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21 January 2018

Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein

1 reference

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21 January 2018

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

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21 January 2018

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

1 reference

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21 January 2018

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

1 reference

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21 January 2018

Identification of c-MYC as a target of the APC pathway

1 reference

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21 January 2018

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

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21 January 2018

Lessons from hereditary colorectal cancer

1 reference

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

1 reference

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21 January 2018

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

1 reference

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21 January 2018

Beta-catenin mutations in cell lines established from human colorectal cancers

1 reference

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21 January 2018

A common human skin tumour is caused by activating mutations in beta-catenin

1 reference

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21 January 2018

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

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21 January 2018

Injected Wnt RNA induces a complete body axis in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M905336199

21 January 2018

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

1 reference

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21 January 2018

Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling

1 reference

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21 January 2018

Grafting of triggering site onto lymphocytes; distribution of grafted dinitrophenyl groups on cell surface glycoproteins and glycolipids

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21 January 2018

Neural and developmental actions of lithium: a unifying hypothesis

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A molecular mechanism for the effect of lithium on development

1 reference

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Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M905336199

21 January 2018

Activation of the Wnt signaling pathway: a molecular mechanism for lithium action.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M905336199

21 January 2018

Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation in Xenopus embryos.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M905336199

21 January 2018

wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M905336199

21 January 2018

Glycogen synthase kinase 3 regulates cell fate in Dictyostelium

1 reference

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M905336199

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A soluble form of Wnt-1 protein with mitogenic activity on mammary epithelial cells

1 reference

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The mouse Wnt-1 gene can act via a paracrine mechanism in transformation of mammary epithelial cells

1 reference

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

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21 January 2018

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M905336199

21 January 2018

PDK1, one of the missing links in insulin signal transduction?

1 reference

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R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

1 reference

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Signal transduction from multiple Ras effectors

1 reference

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Ras-related proteins in signal transduction and growth control

1 reference

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Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

1 reference

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Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

1 reference

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The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

1 reference

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Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

1 reference

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21 January 2018

Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation

1 reference

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21 January 2018

Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

1 reference

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Inhibition of glycogen synthase kinase 3beta activity regulates proliferation of cultured cerebellar granule cells

1 reference

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Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis

1 reference

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21 January 2018

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M905336199

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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