(Q40890980)

24 September 2017

title

SDZ PSC 833 the drug resistance modulator activates cellular ceramide formation by a pathway independent of P-glycoprotein (English)

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24 September 2017

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C W Goulding

1

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24 September 2017

A E Giuliano

series ordinal

2

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24 September 2017

M C Cabot

series ordinal

3

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24 September 2017

language of work or name

English

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publication date

1 February 2000

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24 September 2017

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24 September 2017

volume

149

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24 September 2017

issue

1-2

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24 September 2017

page(s)

143-151

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The biochemistry of P-glycoprotein-mediated multidrug resistance

24 September 2017

cites work

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Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

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Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

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P-glycoprotein, multidrug resistance and tumor progression

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Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro

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7 January 2021

Cyclosporins as drug resistance modifiers

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7 January 2021

The multidrug resistance modulator SDZ PSC 833 is a potent activator of cellular ceramide formation.

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7 January 2021

Effect of combination of suboptimal concentrations of P-glycoprotein blockers on the proliferation of MDR1 gene expressing cells

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7 January 2021

Molecular interactions of cyclosporin A with P-glycoprotein. Photolabeling with cyclosporin derivatives

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The role of ceramide in the cellular response to cytotoxic agents.

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Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells

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Signal transduction of stress via ceramide

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7 January 2021

Programmed cell death induced by ceramide

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Accumulation of glucosylceramides in multidrug-resistant cancer cells

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Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells

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Tamoxifen retards glycosphingolipid metabolism in human cancer cells

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Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein

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Effect of P-glycoprotein expression on sensitivity to hormones in MCF-7 human breast cancer cells

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Immunocytochemical detection of DNA topoisomerase type II in primary breast carcinomas: correlation with clinico-pathological features

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7 January 2021

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

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7 January 2021

Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis

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7 January 2021

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

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7 January 2021

Influence of SDZ-PSC833 on daunorubicin intracellular accumulation in bone marrow specimens from patients with acute myeloid leukaemia.

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7 January 2021

Ceramide signaling in apoptosis

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7 January 2021

10.1016/S0304-3835(99)00353-5

Identifiers

DOI

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24 September 2017

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