(Q40895626)

24 September 2017

Regulators of Glucose Metabolism in CD4(+) and CD8(+) T Cells (English)

1 reference

24 September 2017

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0 references

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26606199%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Clovis S Palmer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26606199%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Tabinda Hussain

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26606199%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Gabriel Duette

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26606199%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Thomas J Weller

4

1 reference

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7 June 2020

Isabel Sada-Ovalle

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26606199%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Suzanne M Crowe

7

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7 June 2020

publication date

25 November 2015

1 reference

International Reviews of Immunology

24 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26606199%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

35

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7 June 2020

issue

6

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7 June 2020

page(s)

477-488

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26606199%20AND%20SRC:MED&resulttype=core&format=json

Regulation of T lymphocyte metabolism

7 June 2020

cites work

1 reference

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Metabolic regulation of T lymphocytes

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Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.

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Glucose metabolism regulates T cell activation, differentiation, and functions.

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Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

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Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells

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Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival

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Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch

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Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells

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The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function

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The nuts and bolts of AGC protein kinases

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PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

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Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism

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Subcellular localization of hexokinases I and II directs the metabolic fate of glucose

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Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.

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mTOR regulates memory CD8 T-cell differentiation

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The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

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mTOR, metabolism, and the regulation of T-cell differentiation and function

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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

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HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

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21 January 2018

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