(Q40906010)

24 September 2017

Activation of the Stat3 signaling pathway is required for differentiation by interleukin-6 in PC12-E2 cells (English)

1 reference

24 September 2017

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Y Y Wu

1

1 reference

PubMed ID

10636920

24 September 2017

R A Bradshaw

series ordinal

2

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PubMed ID

10636920

24 September 2017

language of work or name

English

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publication date

1 January 2000

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Journal of Biological Chemistry

24 September 2017

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24 September 2017

275

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24 September 2017

2147-2156

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24 September 2017

3

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STATs and gene regulation

24 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Reflections on STAT3, STAT5, and STAT6 as fat STATs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Cytokine receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

STATs: signal transducers and activators of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Jaks and STATs: biological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Jak2 is essential for signaling through a variety of cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Interleukin 6 and its receptor: ten years later

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Leukemia inhibitory factor, a cytokine at the interface between neurobiology and immunology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

CNTF, FGF, and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

The neurotrophins and CNTF: two families of collaborative neurotrophic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Cytokines and the nervous system. I: Expression and recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Expression of interleukin-6 receptor (IL-6R) and gp130 mRNA in PC12 cells and sympathetic neurons: modulation by tumor necrosis factor alpha (TNF-alpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Neuroendocrine-immune system interactions and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Sympathetic neurons can produce and respond to interleukin 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Neuronal differentiation factors/cytokines and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Cytokines and the nervous system II: Actions and mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Induction of neurite outgrowth by interleukin-6 is accompanied by activation of Stat3 signaling pathway in a variant PC12 cell (E2) line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Synergistic induction of neurite outgrowth by nerve growth factor or epidermal growth factor and interleukin-6 in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

PC12-E2 cells: a stable variant with altered responses to growth factor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Production of high-titer helper-free retroviruses by transient transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Transcription factors Stat3 and Stat5b are present in rat liver nuclei late in an acute phase response and bind interleukin-6 response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Sequence of protein disulphide isomerase and implications of its relationship to thioredoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

High-efficiency transformation of mammalian cells by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

STAT3 is a serine kinase target in T lymphocytes. Interleukin 2 and T cell antigen receptor signals converge upon serine 727.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Increasing complexity of the Ras signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Differentiation-regulated serine phosphorylation of STAT1 promotes GAF activation in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Requirement of serine phosphorylation for formation of STAT-promoter complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

STAT3 activation by cytokines utilizing gp130 and related transducers involves a secondary modification requiring an H7-sensitive kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

STATs as activators of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

Not just another meeting: the coming of age of JAKs and STATs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.3.2147

21 January 2018

Identifiers

DOI

10.1074/JBC.275.3.2147

1 reference

24 September 2017

1 reference

PubMed ID

10636920