(Q40908835)

24 September 2017

1 reference

title

Identification and preclinical testing of novel antiepileptic compounds (English)

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24 September 2017

Meldrum BS

1

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24 September 2017

1 January 1997

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24 September 2017

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24 September 2017

38 Suppl 9

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24 September 2017

S7-15

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Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation?

24 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Na+ channels as targets for neuroprotective drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Structure and function of voltage-gated ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Flunarizine inhibits both calcium-dependent and -independent release of glutamate from synaptosomes and cultured neurones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Ca(2+)-activated K+ currents in neurones: types, physiological roles and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Recent progress in potassium channel opener pharmacology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Properties of a delayed rectifier potassium current in dentate granule cells isolated from the hippocampus of patients with chronic temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Alkyl-substituted gamma-butyrolactones act at a distinct site allosterically linked to the TBPS/picrotoxinin site on the GABAA receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

A novel allosteric modulatory site on the GABAA receptor beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

The metabotropic glutamate receptors: structure and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Induction or protection of limbic seizures in mice by mGluR subtype selective agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Perceptions of control in adults with epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

A review of the preclinical pharmacology of tiagabine: a potent and selective anticonvulsant GABA uptake inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Extracellular amino acid levels in hippocampus during pilocarpine-induced seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Expression and localization of Na+/H+ exchangers in rat central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

4-amino-hex-5-enoic acid, a selective catalytic inhibitor of 4-aminobutyric-acid aminotransferase in mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Presynaptic GABAB-and gamma-hydroxybutyric acid-mediated mechanisms in generalized absence seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Absence epilepsy in tottering mutant mice is associated with calcium channel defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Identification of pore-forming subunit of P-type calcium channels: an antisense study on rat cerebellar Purkinje cells in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Long-lasting enhancement of metabotropic excitatory amino acid receptor-mediated polyphosphoinositide hydrolysis in the amygdala/ pyriform cortex of deep prepiriform cortical kindled rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

21 January 2018

Targeting epilepsy genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPM1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

A single gene error of noradrenergic axon growth synchronizes central neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

An amino acid exchange in the second transmembrane segment of a neuronal nicotinic receptor causes partial epilepsy by altering its desensitization kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

First Alfred Meyer Memorial Lecture. Epileptic brain damage: a consequence and a cause of seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Limbic seizures increase neuronal production of messenger RNA for nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Neurotrophins and neuronal plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

Hippocampal GABA transporter function in temporal-lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1528-1157.1997.TB05204.X

10.1111/J.1528-1157.1997.TB05204.X

21 January 2018

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

9578540