(Q40910995)

24 September 2017

title

Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer (English)

1 reference

24 September 2017

1 reference

Sabine Merkelbach-Bruse

17

Sabine Merkelbach-Bruse

0 references

Martin Peifer

Martin Peifer

5

0 references

Christoph Engel

Christoph Engel

3

0 references

Peter Propping

15

Peter Propping

1 reference

24 September 2017

8

Alexandra Florin

1 reference

24 September 2017

21

Thomas Zander

1 reference

24 September 2017

20

Lukas Carl Heukamp

1 reference

24 September 2017

18

Margarete Odenthal

1 reference

24 September 2017

7

Helen Kuenstlinger

1 reference

24 September 2017

12

Frank Ueckeroth

1 reference

Ursula Rommerscheidt-Fuss

24 September 2017

9

Ursula Rommerscheidt-Fuss

1 reference

24 September 2017

Michael Kloth

1

1 reference

24 September 2017

Vanessa Ruesseler

2

1 reference

24 September 2017

Katharina Koenig

4

1 reference

24 September 2017

Erika Mariotti

6

1 reference

24 September 2017

Ulrike Koitzsch

10

1 reference

24 September 2017

Claudia Wodtke

11

1 reference

24 September 2017

Stefanie Holzapfel

13

1 reference

24 September 2017

Stefan Aretz

14

1 reference

24 September 2017

Markus Loeffler

16

1 reference

24 September 2017

Nicolaus Friedrichs

19

1 reference

24 September 2017

Reinhard Buettner

22

1 reference

24 September 2017

language of work or name

English

0 references

publication date

28 April 2015

1 reference

24 September 2017

1 reference

24 September 2017

volume

65

1 reference

24 September 2017

issue

8

1 reference

24 September 2017

page(s)

1296-1305

1 reference

A genetic model for colorectal tumorigenesis

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Colorectal cancer molecular biology moves into clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Comprehensive molecular characterization of human colon and rectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Proximal adenomas in hereditary non-polyposis colorectal cancer are prone to rapid malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Clinical relevance of microsatellite instability in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Fast and accurate long-read alignment with Burrows-Wheeler transform

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

The Sequence Alignment/Map format and SAMtools

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

The landscape of microsatellite instability in colorectal and endometrial cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Predicting the functional impact of protein mutations: application to cancer genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Activating HER2 mutations in HER2 gene amplification negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Implementation of universal microsatellite instability and immunohistochemistry screening for diagnosing lynch syndrome in a large academic medical center.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Microsatellite instability detection by next generation sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

A novel approach for characterizing microsatellite instability in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

The mutational burdens and evolutionary ages of early gastric cancers are comparable to those of advanced gastric cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Genetic reconstruction of individual colorectal tumor histories

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Microsatellite instability in aberrant crypt foci from patients without concurrent colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

EXEL-7647 inhibits mutant forms of ErbB2 associated with lapatinib resistance and neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

ERBB2 gene as a potential therapeutic target in small bowel adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Comprehensive molecular characterization of gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-309026

10.1136/GUTJNL-2014-309026

21 January 2018

Identifiers

DOI

1 reference

24 September 2017

1 reference