(Q40916856)

24 September 2017

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway (English)

1 reference

24 September 2017

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Risa Kitagawa

1

1 reference

24 September 2017

Christopher J Bakkenist

series ordinal

2

1 reference

24 September 2017

Peter J McKinnon

series ordinal

3

1 reference

24 September 2017

Michael B Kastan

series ordinal

4

1 reference

24 September 2017

language of work or name

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2 June 2004

1 reference

24 September 2017

1 reference

24 September 2017

18

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24 September 2017

12

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24 September 2017

1423-1438

1 reference

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

The Mre11 complex is required for ATM activation and the G2/M checkpoint

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Requirement of the MRN complex for ATM activation by DNA damage

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

BRCA1 supports XIST RNA concentration on the inactive X chromosome

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

ATM: genome stability, neuronal development, and cancer cross paths

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

The many substrates and functions of ATM

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

DNA damage-dependent nuclear dynamics of the Mre11 complex

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

The DNA damage response: putting checkpoints in perspective

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Monoclonal antibodies generated against recombinant ATM support kinase activity

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Independence of R/M/N focus formation and the presence of intact BRCA1.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Enhanced phosphorylation of p53 by ATM in response to DNA damage

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

DNA damage induces phosphorylation of the amino terminus of p53

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Cohesins: chromosomal proteins that prevent premature separation of sister chromatids

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Fragments of ATM which have dominant-negative or complementing activity

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

A mammalian protein complex that repairs double-strand breaks and deletions by recombination.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

SMC proteins constitute two subunits of the mammalian recombination complex RC-1.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Cloning and characterization of mammalian SMC1 and SMC3 genes and proteins, components of the DNA recombination complexes RC-1.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

DNA replication-dependent nuclear dynamics of the Mre11 complex.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423193

Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest

19 August 2018

1 reference

12 December 2020

In vivo site-directed mutagenesis of yeast plasmids using a three-fragment homologous recombination system

1 reference

12 December 2020

Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage

1 reference

12 December 2020

The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia

1 reference

12 December 2020

Influence of ATM function on telomere metabolism

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.1200304

1 reference

24 September 2017

1 reference

24 September 2017

PubMed publication ID

15175241

1 reference