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Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice
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scholarly article
1 reference
stated in
PubMed
PubMed ID
14690604
retrieved
24 January 2017
title
Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice
(English)
1 reference
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PubMed
PubMed ID
14690604
retrieved
24 January 2017
main subject
maternal health
0 references
MRE11A homolog A, double strand break repair nuclease
1 reference
stated in
GOA release 2020-03-11
author
John Petrini
series ordinal
7
object named as
John H. J. Petrini
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PubMed
PubMed ID
14690604
retrieved
24 January 2017
author name string
Jan-Willem F. Theunissen
series ordinal
1
1 reference
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PubMed
PubMed ID
14690604
retrieved
24 January 2017
Mark I. Kaplan
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
14690604
retrieved
24 January 2017
Patricia A. Hunt
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
14690604
retrieved
24 January 2017
Bret R. Williams
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4
1 reference
stated in
PubMed
PubMed ID
14690604
retrieved
24 January 2017
David O. Ferguson
series ordinal
5
1 reference
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PubMed
PubMed ID
14690604
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24 January 2017
Frederick W. Alt
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
14690604
retrieved
24 January 2017
publication date
1 December 2003
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stated in
PubMed
PubMed ID
14690604
retrieved
24 January 2017
published in
Molecular Cell
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stated in
PubMed
PubMed ID
14690604
retrieved
24 January 2017
volume
12
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PubMed
PubMed ID
14690604
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24 January 2017
page(s)
1511–1523
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PubMed
PubMed ID
14690604
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24 January 2017
issue
6
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PubMed
PubMed ID
14690604
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24 January 2017
cites work
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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inferred from DOI database lookup
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.
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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles.
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reference URL
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CHK2 kinase--a busy messenger.
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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Analysis of a malsegregating mouse Y chromosome: evidence that the earliest cleavage divisions of the mammalian embryo are non-disjunction-prone
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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Cancer predisposition and hematopoietic failure in Rad50(S/S) mice
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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
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Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants
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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.
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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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Human Rad50/Mre11 is a flexible complex that can tether DNA ends
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
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Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
1 reference
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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
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The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
MDC1 is required for the intra-S-phase DNA damage checkpoint
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
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Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The many interfaces of Mre11
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
A family showing no evidence of linkage between the ataxia telangiectasia gene and chromosome 11q22-23.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene.
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation dynamics of imprinted genes in mouse germ cells.
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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
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Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage during mitosis in human cells delays the metaphase/anaphase transition via the spindle-assembly checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage-dependent nuclear dynamics of the Mre11 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In situ visualization of DNA double-strand break repair in human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
S-phase functions of the Mre11 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cellular response to DNA double-strand breaks: defining the sensors and mediators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissecting p53 tumor suppressor functions in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATM and related protein kinases: safeguarding genome integrity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MDC1 is a mediator of the mammalian DNA damage checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homologous recombination is required for the viability of rad27 mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complex formation and functional versatility of Mre11 of budding yeast in recombination
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
A DNA damage response pathway controlled by Tel1 and the Mre11 complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The coiled-coil of the human Rad50 DNA repair protein contains specific segments of increased flexibility
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A murine model of Nijmegen breakage syndrome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromosomal influence on meiotic spindle assembly: abnormal meiosis I in female Mlh1 mutant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual roles of ATM in the cellular response to radiation and in cell growth control.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engineering mouse chromosomes with Cre-loxP: range, efficiency, and somatic applications
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900455-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1097-2765(03)00455-6
0 references
PubMed ID
14690604
1 reference
stated in
PubMed
PubMed ID
14690604
retrieved
24 January 2017
ResearchGate publication ID
5542034
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