(Q40925430)

English

The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype

scientific article published on September 1995

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype (English)

1 reference

Europe PubMed Central

24 September 2017

author name string

Levine AJ

1

1 reference

Europe PubMed Central

24 September 2017

Wu MC

2

1 reference

Europe PubMed Central

24 September 2017

Chang A

3

1 reference

Europe PubMed Central

24 September 2017

Silver A

4

1 reference

Europe PubMed Central

24 September 2017

Attiyeh EF

5

1 reference

Europe PubMed Central

24 September 2017

Lin J

6

1 reference

Europe PubMed Central

24 September 2017

Epstein CB

7

1 reference

Europe PubMed Central

24 September 2017

language of work or name

0 references

publication date

1 September 1995

1 reference

Europe PubMed Central

24 September 2017

Annals of the New York Academy of Sciences

1 reference

Europe PubMed Central

24 September 2017

768

1 reference

Europe PubMed Central

24 September 2017

111-128

1 reference

Europe PubMed Central

24 September 2017

Clinical implications of the p53 tumor-suppressor gene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

The p53 proto-oncogene can act as a suppressor of transformation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Wild-type p53 can inhibit oncogene-mediated focus formation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Genetic mechanisms of tumor suppression by the human p53 gene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Presence of a potent transcription activating sequence in the p53 protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

A transcriptionally active DNA-binding site for human p53 protein complexes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Definition of a consensus binding site for p53

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Sequence-specific transcriptional activation is essential for growth suppression by p53.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Thymocyte apoptosis induced by p53-dependent and independent pathways.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

p53 domains: identification and characterization of two autonomous DNA-binding regions.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Isolation of a full-length mouse cDNA clone coding for an immunologically distinct p53 molecule

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Endogenous p53 protein generated from wild-type alternatively spliced p53 RNA in mouse epidermal cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Mutations in the p53 gene occur in diverse human tumour types

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

p53: a frequent target for genetic abnormalities in lung cancer.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Sequence specificity in aflatoxin B1--DNA interactions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Base substitution mutations induced by metabolically activated aflatoxin B1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

The p53-mdm-2 autoregulatory feedback loop

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Gain of function mutations in p53.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Mammalian p53 can function as a transcription factor in yeast

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Wild-type p53 activates transcription in vitro

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.1995.TB12115.X

21 January 2018

Identifiers

10.1111/J.1749-6632.1995.TB12115.X

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40925430&oldid=2092706867"