(Q40933853)

English

The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors

scientific article published on February 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors (English)

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

Andisheh Abedini

object named as

Andisheh Abedini

3

0 references

Daniel P Raleigh

object named as

Daniel P Raleigh

4

0 references

author name string

Ping Cao

1

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

Fanling Meng

2

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

language of work or name

0 references

publication date

1 February 2010

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

49

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

872-881

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

Animal models of human amyloidoses: are transgenic mice worth the time and trouble?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

A role for helical intermediates in amyloid formation by natively unfolded polypeptides?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Structure of alpha-helical membrane-bound human islet amyloid polypeptide and its implications for membrane-mediated misfolding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Longitudinal ultrastructure study of islet amyloid in the HIP rat model of type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Direct detection of transient alpha-helical states in islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Protein misfolding, functional amyloid, and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Inhibition of amyloid fibril formation by polyphenols: structural similarity and aromatic interactions as a common inhibition mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Islet amyloid development in a mouse strain lacking endogenous islet amyloid polypeptide (IAPP) but expressing human IAPP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Amylin compared with calcitonin gene-related peptide: structure, biology, and relevance to metabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Evidence that the leucine zipper is a coiled coil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

25 September 2017

Helix stabilization precedes aqueous and bilayer-catalyzed fiber formation in islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

17 June 2018

Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

17 June 2018

Spontaneous diabetes in hemizygous human amylin transgenic mice that developed neither islet amyloid nor peripheral insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

17 June 2018

Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

17 June 2018

Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

17 June 2018

Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

17 June 2018

Residual structure in islet amyloid polypeptide mediates its interactions with soluble insulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Amylin proprotein processing generates progressively more amyloidogenic peptides that initially sample the helical state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Lipid membranes modulate the structure of islet amyloid polypeptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Formation of amyloid in human pancreatic islets transplanted to the liver and spleen of nude mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

The mechanism of insulin action on islet amyloid polypeptide fiber formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Human islet amyloid polypeptide transgenic mice as a model of non-insulin-dependent diabetes mellitus (NIDDM).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

19 August 2018

Anin vitromodel of early islet amyloid polypeptide (IAPP) fibrillogenesis using human IAPP-transgenic mouse islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

2 December 2018

Conserved and Cooperative Assembly of Membrane-Bound α-Helical States of Islet Amyloid Polypeptide†

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882292

2 December 2018

Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of islet amyloid fibrils in beta-secretory granules of transgenic mice expressing human islet amyloid polypeptide/amylin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of beta cell granule components on human islet amyloid polypeptide fibril formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporation of Pseudoproline Derivatives Allows the Facile Synthesis of Human IAPP, a Highly Amyloidogenic and Aggregation-Prone Polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mapping of the recognition interface between the islet amyloid polypeptide and insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Single-Point Mutation Converts the Highly Amyloidogenic Human Islet Amyloid Polypeptide into a Potent Fibrillization Inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread amyloid deposition in transplanted human pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20028124

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI901751B

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

25 September 2017

ResearchGate publication ID

0 references

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