(Q40954780)

25 September 2017

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title

CpG DNA: a pathogenic factor in systemic lupus erythematosus? (English)

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25 September 2017

A M Krieg

1

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25 September 2017

1 November 1995

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Journal of Clinical Immunology

25 September 2017

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25 September 2017

15

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25 September 2017

284-292

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25 September 2017

6

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https://scigraph.springernature.com/pub.10.1007/bf01541318

25 September 2017

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Interferons and interferon inducers in cancer treatment

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Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity

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Quantitation and characterization of plasma DNA in normals and patients with systemic lupus erythematosus

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DNA binding to human leukocytes. Evidence for a receptor-mediated association, internalization, and degradation of DNA

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Nucleosomes and DNA bind to specific cell-surface molecules on murine cells and induce cytokine production

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Membrane-Associated DNA in the Cytoplasm of Diploid Human Lymphocytes

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Haemodialysis as a model for studying endogenous plasma DNA: oligonucleosome-like structure and clearance

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Antitumor activity of deoxyribonucleic acid fraction from Mycobacterium bovis BCG. I. Isolation, physicochemical characterization, and antitumor activity

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Analysis of oligonucleotide binding, internalization, and intracellular trafficking utilizing a novel radiolabeled crosslinker

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Antigen DNA isolated from immune complexes in plasma of patients with systemic lupus erythematosus hybridizes with the Escherichia coli lac Z gene

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12 December 2020

Circulating DNA in systemic lupus erythematosus. Isolation and characterization

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12 December 2020

DNA of free and complexed origin in human plasma: Concentration and length distribution

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12 December 2020

Polyinosinic-polycytidylic acid complexed with poly-L-lysine and carboxymethylcellulose in combination with interleukin 2 in patients with cancer: clinical and immunological effects

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Mechanism of oligonucleotide uptake by cells: involvement of specific receptors?

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12 December 2020

Immunomodulation of natural killer activity by polyribonucleotides

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12 December 2020

Free DNA in serum and plasma from normal adults

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12 December 2020

Partial purification and characterization of plasma DNA and its relation to disease activity in systemic lupus erythematosus

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12 December 2020

The site and stage of anti-DNA B-cell deletion.

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12 December 2020

Pharmacokinetics of a 14C-labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats

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12 December 2020

Demonstration of extrinsic DNA from immune complexes in plasma of a patient with systemic lupus erythematosus.

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12 December 2020

Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN [correction of INF] and augment IFN-mediated [correction of INF] natural killer activity

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12 December 2020

Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus

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12 December 2020

Lymphokine-like activity of 8-mercaptoguanosine: induction of T and B cell differentiation

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12 December 2020

Characterization of oligonucleotide transport into living cells

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12 December 2020

Biodistribution and metabolism of internally 3H-labeled oligonucleotides. I. Comparison of a phosphodiester and a phosphorothioate

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12 December 2020

CpG motifs in bacterial DNA trigger direct B-cell activation

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12 December 2020

Mechanism of synergy between T cell signals and C8-substituted guanine nucleosides in humoral immunity: B lymphotropic cytokines induce responsiveness to 8-mercaptoguanosine

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12 December 2020

Demonstration of activation of B lymphocytes in New Zealand black mice at birth by an immunoradiometric assay for murine IgM

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12 December 2020

Synthesis of IgM by cells of NZB and SWR mice and their crosses

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12 December 2020

Antibody binding of macromolecular DNA and RNA in the plasma of SLE patients

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12 December 2020

Selection of antisense oligonucleotides on the basis of genomic frequency of the target sequence.

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12 December 2020

Potential Z-DNA-forming elements in serum DNA from human systemic lupus erythematosus

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12 December 2020

DNA from bacteria, but not from vertebrates, induces interferons, activates natural killer cells and inhibits tumor growth

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Comparison of cellular binding and uptake of antisense phosphodiester, phosphorothioate, and mixed phosphorothioate and methylphosphonate oligonucleotides.

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A role for endogenous retroviral sequences in the regulation of lymphocyte activation

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Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo

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Stimulation of in vitro murine lymphocyte proliferation by bacterial DNA.

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12 December 2020

B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40

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12 December 2020

Induction of anti-double stranded DNA antibodies in normal mice by immunization with bacterial DNA

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12 December 2020

Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone

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12 December 2020

Polyclonal B cell activation in lupus-prone mice precedes and predicts the development of autoimmune disease

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12 December 2020

Cell-surface-associated nucleic acid in tumorigenic cells made visible with platinum-pyrimidine complexes by electron microscopy

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12 December 2020

Effect of DNA size and strandedness on the in vivo clearance and organ localization of DNA.

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12 December 2020

Uptake of Oligodeoxyribonucleotides by Lymphoid Cells Is Heterogeneous and Inducible

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12 December 2020

In vitro augmentation of natural killer cell activity and production of interferon-alpha/beta and -gamma with deoxyribonucleic acid fraction from Mycobacterium bovis BCG.

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12 December 2020

Nuclear DNA degradation in lymphocytes of patients with systemic lupus erythematosus

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12 December 2020

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

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12 December 2020

DEFECTIVE DNA-RECEPTOR FUNCTION IN SYSTEMIC LUPUS ERYTHEMATOSUS AND RELATED DISEASES: EVIDENCE FOR AN AUTOANTIBODY INFLUENCING CELL PHYSIOLOGY

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12 December 2020

Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands

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12 December 2020

Dna isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content

1 reference

12 December 2020

Binding properties of human anti-DNA antibodies to cloned human DNA fragments

1 reference

12 December 2020

DNA methylation and its possible biological roles

1 reference

12 December 2020

Oligonucleotide sequences required for natural killer cell activation

1 reference

12 December 2020

Growth regulation of the B lymphoma cell line WEHI-231 by anti-immunoglobulin, lipopolysaccharide, and other bacterial products.

1 reference

12 December 2020

Treating activated CD4+ T cells with either of two distinct DNA methyltransferase inhibitors, 5-azacytidine or procainamide, is sufficient to cause a lupus-like disease in syngeneic mice

1 reference

12 December 2020

Pharmacokinetics of antisense oligonucleotides

1 reference

12 December 2020

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

1 reference

12 December 2020

Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes

1 reference

12 December 2020

A synthetic single-stranded DNA, poly(dG,dC), induces interferon-alpha/beta and -gamma, augments natural killer activity, and suppresses tumor growth

1 reference

12 December 2020

DNA receptor dysfunction in systemic lupus erythematosus and kindred disorders. Induction by anti-DNA antibodies, antihistone antibodies, and antireceptor antibodies

1 reference

12 December 2020

Plasma DNA in systemic lupus erythematosus. Characterization of cloned base sequences

1 reference

12 December 2020

CpG-rich islands and the function of DNA methylation

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01541318

1 reference

PubMed ID

8576314

Dimensions Publication ID

25 September 2017

0 references

1 reference

PubMed ID

8576314