(Q40958349)

English

Synthesis of thiophenecarboxamides, thieno[3,4-c]pyridin-4(5H)-ones and thieno[3,4-d]pyrimidin-4(3H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).

scientific article published on February 1999

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 September 2017

Synthesis of thiophenecarboxamides, thieno[3,4-c]pyridin-4(5H)-ones and thieno[3,4-d]pyrimidin-4(3H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP). (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

author name string

Shinkwin AE

1

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Europe PubMed Central

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25 September 2017

Whish WJ

2

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Europe PubMed Central

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25 September 2017

Threadgill MD

3

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Europe PubMed Central

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25 September 2017

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publication date

1 February 1999

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25 September 2017

Bioorganic & Medicinal Chemistry

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25 September 2017

7

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Europe PubMed Central

PubMed publication ID

25 September 2017

2

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Europe PubMed Central

PubMed publication ID

25 September 2017

297-308

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Europe PubMed Central

PubMed publication ID

25 September 2017

Cellular Radiosensitivity and Tumor Radiation Response in the EMT6 Tumor Cell System

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The gross response of an experimental tumour to single doses of x-rays

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(ADP-ribose)n participates in DNA excision repair

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The function of poly (ADP-ribosylation) in DNA breakage and rejoining

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Role of poly(ADP-ribose) formation in DNA repair

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Inhibitors of Poly(ADP-Ribose) Synthesis Enhance X-Ray Killing of Log-Phase Chinese Hamster Cells

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Inhibition of Gamma-Ray Dose-Rate Effects by D 2 O and Inhibitors of Poly(ADP-Ribose) Synthetase in Cultured Mammalian L5178Y Cells

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The role of inhibitors of poly(ADP-ribose) polymerase as resistance-modifying agents in cancer therapy.

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Enhancement of alkylating agent activity in vitro by PD 128763, a potent poly(ADP-ribose) synthetase inhibitor

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Potentiation of the antitumor activity of cisplatin in mice by 3-aminobenzamide and nicotinamide

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3-aminobenzamide and/or O6-benzylguanine evaluated as an adjuvant to temozolomide or BCNU treatment in cell lines of variable mismatch repair status and O6-alkylguanine-DNA alkyltransferase activity

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Potentiation of temozolomide-induced cytotoxicity: a comparative study of the biological effects of poly(ADP-ribose) polymerase inhibitors

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Poly(ADP-ribosylation) as target for cancer chemotherapy

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DNA strand break-mediated partitioning of poly(ADP-ribose) polymerase function

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Novel inhibitors of poly(ADP-ribose) synthetase

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Analogues of benzamide as poly(ADP-ribose)transferase inhibitors: a study on structure activity relationships

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Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).

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CCXLIV.—Replacement of halogen in orthobromo-benzoic acid

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Studies on Hydrogen Exchange. IX. Electrophilic Deuteration of 2-Pyridinol, 2-Quinolinol, and 1-Isoquinolinol

1 reference

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Tetrahydrothiophene (thiophane) derivatives

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Alkaline cleavage of unsymmetrical beta-diketones; ring opening of acylcylohexanones to form epsilon-acyl caproic acids

1 reference

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Identifiers

10.1016/S0968-0896(98)00210-7

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 September 2017

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