(Q40977903)

25 September 2017

Structure enabled design of BAZ2-ICR, a chemical probe targeting the bromodomains of BAZ2A and BAZ2B. (English)

1 reference

25 September 2017

15

1 reference

25 September 2017

4

Apirat Chaikuad

0 references

Lewis R Vidler

Lewis R Vidler

3

0 references

Susanne Müller

Susanne Müller

14

0 references

Florence Raynaud

Florence Raynaud

13

0 references

Cynthia Tallant

6

Cynthia Tallant

1 reference

25 September 2017

Ludovic Drouin

1

1 reference

25 September 2017

Sally McGrath

2

1 reference

25 September 2017

Octovia Monteiro

5

1 reference

25 September 2017

Martin Philpott

7

1 reference

25 September 2017

Catherine Rogers

8

1 reference

25 September 2017

Oleg Fedorov

9

1 reference

25 September 2017

Manjuan Liu

10

1 reference

25 September 2017

Wasim Akhtar

11

1 reference

25 September 2017

Angela Hayes

12

1 reference

25 September 2017

Swen Hoelder

16

1 reference

25 September 2017

language of work or name

English

0 references

publication date

26 February 2015

1 reference

Journal of Medicinal Chemistry

25 September 2017

1 reference

25 September 2017

58

1 reference

25 September 2017

5

1 reference

25 September 2017

2553-2559

1 reference

BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Targeting bromodomains: epigenetic readers of lysine acetylation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Targeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B Bromodomain

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Fragment-based hit identification: thinking in 3D.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

The bromodomain interaction module

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Histone recognition and large-scale structural analysis of the human bromodomain family

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Bromodomains as therapeutic targets

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

High content pharmacophores from molecular fields: a biologically relevant method for comparing and understanding ligands

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Aromatic rings in chemical and biological recognition: energetics and structures

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Selective inhibition of BET bromodomains

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Recognizing and exploiting differences between RNAi and small-molecule inhibitors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

A novel family of bromodomain genes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Druggability analysis and structural classification of bromodomain acetyl-lysine binding sites

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Bromodomain-peptide displacement assays for interactome mapping and inhibitor discovery

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4441536

Intramolecular pi-stacking interaction in a rigid molecular hinge substituted with 1-(pyrenylethynyl) units

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25719566

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JM501963E

1 reference

25 September 2017

1 reference

25 September 2017

PubMed publication ID

25719566

1 reference