(Q40993638)

25 September 2017

title

Interaction with P-glycoprotein and transport of erythromycin, midazolam and ketoconazole in Caco-2 cells (English)

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25 September 2017

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Takano M

1

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25 September 2017

Hasegawa R

2

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25 September 2017

Fukuda T

3

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25 September 2017

Yumoto R

4

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25 September 2017

Nagai J

5

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25 September 2017

Murakami T

6

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25 September 2017

language of work or name

English

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publication date

1 October 1998

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European Journal of Pharmacology

25 September 2017

published in

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25 September 2017

volume

358

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25 September 2017

issue

3

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25 September 2017

page(s)

289-294

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

25 September 2017

cites work

1 reference

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7 January 2021

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Tacrolimus oral bioavailability doubles with coadministration of ketoconazole

7 January 2021

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Expression of a multidrug-resistance gene in human tumors and tissues

7 January 2021

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Biochemistry of multidrug resistance mediated by the multidrug transporter

7 January 2021

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The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa

7 January 2021

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Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Possible interaction between cyclosporine and erythromycin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine

7 January 2021

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Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

A potentially hazardous interaction between erythromycin and midazolam.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Human MDR1 and mouse mdr1a P-glycoprotein alter the cellular retention and disposition of erythromycin, but not of retinoic acid or benzo(a)pyrene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Evaluation of the intestinal absorption of erythromycin in man: absolute bioavailability and comparison with enteric coated erythromycin

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Relationship between expression level of P-glycoprotein and daunorubicin transport in LLC-PK1 cells transfected with human MDR1 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

7 January 2021

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Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

Polarized transport of docetaxel and vinblastine mediated by P-glycoprotein in human intestinal epithelial cell monolayers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man--fact or myth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2898%2900607-4

10.1016/S0014-2999(98)00607-4

7 January 2021

Identifiers

DOI

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25 September 2017

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