(Q40997357)

25 September 2017

title

Effect of chloroquine and leupeptin on intracellular accumulation of amyloid-beta (A beta) 1-42 peptide in a murine N9 microglial cell line (English)

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25 September 2017

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T Chu

1

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25 September 2017

T Tran

2

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25 September 2017

F Yang

3

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25 September 2017

W Beech

4

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25 September 2017

G M Cole

5

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25 September 2017

S A Frautschy

6

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25 September 2017

language of work or name

English

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publication date

1 October 1998

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25 September 2017

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25 September 2017

volume

436

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25 September 2017

issue

3

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25 September 2017

page(s)

439-444

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

25 September 2017

cites work

1 reference

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A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene.

21 January 2018

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

21 January 2018

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Production of the Alzheimer amyloid beta protein by normal proteolytic processing

21 January 2018

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Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

21 January 2018

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Rapid cellular uptake of Alzheimer amyloid betaA4 peptide by cultured human neuroblastoma cells

21 January 2018

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Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

21 January 2018

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Amyloid beta protein (A beta) removal by neuroglial cells in culture

21 January 2018

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Scavenging of Alzheimer's amyloid beta-protein by microglia in culture.

21 January 2018

1 reference

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Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

21 January 2018

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Evidence for lysosomal processing of amyloid beta-protein precursor in cultured cells.

21 January 2018

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

21 January 2018

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Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

21 January 2018

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Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain

21 January 2018

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Inducible nitric oxide synthase activity of cloned murine microglial cells

21 January 2018

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beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

21 January 2018

1 reference

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Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

21 January 2018

1 reference

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Intracellular accumulation and resistance to degradation of the Alzheimer amyloid A4/beta protein

21 January 2018

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Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells.

21 January 2018

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Degradation of amyloid beta-protein by a metalloprotease secreted by microglia and other neural and non-neural cells

21 January 2018

1 reference

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beta-Amyloid peptide produced in vitro is degraded by proteinases released by cultured cells

21 January 2018

1 reference

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Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease

21 January 2018

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Cathepsin D is involved in the clearance of Alzheimer's beta-amyloid protein.

21 January 2018

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Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons

21 January 2018

1 reference

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Deposition of ?/A4 protein along neuronal plasma membranes in diffuse senile plaques

21 January 2018

1 reference

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Preferential adsorption, internalization and resistance to degradation of the major isoform of the Alzheimer's amyloid peptide, A beta 1-42, in differentiated PC12 cells

21 January 2018

1 reference

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Proteolytic degradation of Alzheimer's disease amyloid beta-peptide by a metalloproteinase from microglia cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901161-2

Colocalization of lysosomal hydrolase and beta-amyloid in diffuse plaques of the cerebellum and striatum in Alzheimer's disease and Down's syndrome

7 January 2021

1 reference

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Monoclonal antibody to the C-terminus of beta-amyloid.

7 January 2021

1 reference

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59 Inhibitors of lysosomal function

7 January 2021

1 reference

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Differential effects of proteinase inhibitors and amines on the lysosomal and non-lysosomal pathways of protein degradation in isolated rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901161-2

Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901161-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901161-2

Degradation of Alzheimer's beta-amyloid protein by human cathepsin D.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2898%2901161-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-5793(98)01161-2

1 reference

25 September 2017

1 reference