(Q41006421)

25 September 2017

Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin (English)

1 reference

protein-protein interaction

25 September 2017

1 reference

Lucy Remnant

3

0 references

Anne-Sophie Huart

Anne-Sophie Huart

4

0 references

Alan R Healy

Alan R Healy

1

0 references

Petr Müller

Petr Muller

8

0 references

Nicholas J Westwood

Nicholas J Westwood

14

0 references

Borek Vojtesek

11

Borek Vojtesek

1 reference

25 September 2017

15

Ted R Hupp

1 reference

25 September 2017

Douglas R Houston

2

1 reference

25 September 2017

Veronika Brychtova

5

1 reference

25 September 2017

Magda M Maslon

6

1 reference

25 September 2017

Olivia Meers

7

1 reference

25 September 2017

Adam Krejci

9

1 reference

25 September 2017

Elizabeth A Blackburn

10

1 reference

25 September 2017

Lenka Hernychova

12

1 reference

25 September 2017

Malcolm D Walkinshaw

13

1 reference

25 September 2017

20 March 2015

1 reference

25 September 2017

1 reference

25 September 2017

6

1 reference

25 September 2017

5

1 reference

25 September 2017

3109-3116

1 reference

Reptin and Pontin oligomerization and activity are modulated through histone H3 N-terminal tail interaction

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

A million peptide motifs for the molecular biologist

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Design, synthesis and biological evaluation of Pontin ATPase inhibitors through a molecular docking approach.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

The eukaryotic linear motif resource ELM: 10 years and counting

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Identification of a second Nutlin-3 responsive interaction site in the N-terminal domain of MDM2 using hydrogen/deuterium exchange mass spectrometry

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Nucleotide Binding and Conformational Switching in the Hexameric Ring of a AAA+ Machine

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Chaperone-like activity of the AAA+ proteins Rvb1 and Rvb2 in the assembly of various complexes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

2P2Idb: a structural database dedicated to orthosteric modulation of protein-protein interactions.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Large-scale conformational flexibility determines the properties of AAA+ TIP49 ATPases

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Structural biology and drug discovery for protein-protein interactions.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complex

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

The multifaceted proteins Reptin and Pontin as major players in cancer

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

A divergent substrate-binding loop within the pro-oncogenic protein anterior gradient-2 forms a docking site for Reptin

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Comparison of the multiple oligomeric structures observed for the Rvb1 and Rvb2 proteins

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Linear Motif Atlas for Phosphorylation-Dependent Signaling

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

The AAA+ superfamily of functionally diverse proteins

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Ligand discovery and virtual screening using the program LIDAEUS.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Crystal structure of the human AAA+ protein RuvBL1.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Genome-wide transcriptional analysis of flagellar regeneration in Chlamydomonas reinhardtii identifies orthologs of ciliary disease genes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

A chromatin remodelling complex involved in transcription and DNA processing.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Exhaustive benchmarking of the yeast two-hybrid system.

26 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

Oligomeric assembly and interactions within the human RuvB-like RuvBL1 and RuvBL2 complexes

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5490336

The emergence of the conserved AAA+ ATPases Pontin and Reptin on the signaling landscape

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1039%2FC4SC03885A

On the supertertiary structure of proteins

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28706685

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increasing the dynamic range of in situ PLA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28706685

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1039/C4SC03885A

1 reference

25 September 2017

1 reference

25 September 2017

PubMed publication ID

28706685

1 reference