(Q41031984)

25 September 2017

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title

New clues to Alzheimer's disease: unraveling the roles of amyloid and tau. (English)

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25 September 2017

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Yankner BA

1

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25 September 2017

language of work or name

English

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publication date

1 August 1996

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25 September 2017

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25 September 2017

volume

2

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25 September 2017

issue

8

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25 September 2017

page(s)

850-852

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

25 September 2017

cites work

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https://api.crossref.org/works/10.1038%2FNM0896-850

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

Glycosylation of microtubule-associated protein tau: an abnormal posttranslational modification in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://api.crossref.org/works/10.1038%2FNM0896-850

7 January 2021

Identifiers

DOI

10.1038/NM0896-850

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Dimensions Publication ID

25 September 2017

1011349244

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