(Q41056504)

26 September 2017

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title

Glutamate and Parkinson's disease (English)

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26 September 2017

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1

Blandini F

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26 September 2017

2

Porter RH

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26 September 2017

3

Greenamyre JT

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PubMed ID

8732541

26 September 2017

language of work or name

English

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publication date

1 February 1996

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26 September 2017

Molecular Neurobiology

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26 September 2017

12

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26 September 2017

73-94

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26 September 2017

1

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https://scigraph.springernature.com/pub.10.1007/bf02740748

26 September 2017

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cites work

The role of glutamate in neurotransmission and in neurologic disease

1 reference

https://api.crossref.org/works/10.1007%2FBF02740748

Alternative excitotoxic hypotheses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740748

Iron and aluminium in relation to brain ferritin in normal individuals and Alzheimer's-disease and chronic renal-dialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740748

Functional metabolic mapping of the rat brain during unilateral electrical stimulation of the subthalamic nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02740748

Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease

21 January 2018

1 reference

12 December 2020

Cytosolic ionized calcium and bleb formation after acute cell injury of cultured rabbit renal tubule cells.

1 reference

12 December 2020

The functional anatomy of basal ganglia disorders

1 reference

12 December 2020

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

1 reference

12 December 2020

GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses.

1 reference

12 December 2020

Uptake, release, and subcellular localization of 1-methyl-4-phenylpyridinium in blood platelets

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12 December 2020

Localization of AMPA-selective excitatory amino acid receptor subunits in identified populations of striatal neurons

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12 December 2020

URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit

1 reference

12 December 2020

Feline subthalamic nucleus neurons contain glutamate-like but not GABA-like or glycine-like immunoreactivity

1 reference

12 December 2020

Magnesium gates glutamate-activated channels in mouse central neurones

1 reference

12 December 2020

Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study.

1 reference

12 December 2020

Oxidative damage in neurodegenerative disease

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12 December 2020

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

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12 December 2020

Excitatory Amino Acid Transmitters

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12 December 2020

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons.

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12 December 2020

Reversal of rigidity and improvement in motor performance by subthalamic high-frequency stimulation in MPTP-treated monkeys

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12 December 2020

Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations.

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12 December 2020

Molecular diversity of glutamate receptors and implications for brain function

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12 December 2020

The mitochondrial electron transport and oxidative phosphorylation system

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12 December 2020

Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate

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12 December 2020

N-methyl-D-aspartic acid receptor structure and function

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12 December 2020

Relationships between the neuronal sodium/potassium pump and energy metabolism. Effects of K+, Na+, and adenosine triphosphate in isolated brain synaptosomes

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12 December 2020

Neurons of the subthalamic nucleus in primates display glutamate but not GABA immunoreactivity

1 reference

12 December 2020

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

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12 December 2020

Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement

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12 December 2020

Regionally distinct N-methyl-D-aspartate receptors distinguished by quantitative autoradiography of [3H]MK-801 binding in rat brain.

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12 December 2020

A role for non-NMDA excitatory amino acid receptors in regulating the basal activity of rat globus pallidus neurons and their activation by the subthalamic nucleus

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12 December 2020

Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease

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12 December 2020

Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia

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12 December 2020

Assay of [3H]dihydrorotenone binding to complex I in intact human platelets.

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12 December 2020

The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys

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12 December 2020

Endogenous excitatory amino acids tonically stimulate striatal acetylcholine release through NMDA but not AMPA receptors

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12 December 2020

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

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12 December 2020

Changes of respiratory chain activity in mitochondrial and synaptosomal fractions isolated from the gerbil brain after graded ischaemia

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12 December 2020

Exacerbation of NMDA, AMPA, and L-glutamate excitotoxicity by the succinate dehydrogenase inhibitor malonate

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12 December 2020

Decreased ferritin levels in brain in Parkinson's disease

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12 December 2020

Inhibition of succinate dehydrogenase by malonic acid produces an "excitotoxic" lesion in rat striatum

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12 December 2020

Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.

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12 December 2020

NMDA antagonists potentiate antiparkinsonian actions of L-dopa in monoamine-depleted rats

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12 December 2020

Chemically induced hypoglycemia and anoxia: relationship to glutamate receptor-mediated toxicity in retina

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12 December 2020

Oxidative stress, glutamate, and neurodegenerative disorders

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12 December 2020

Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase.

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12 December 2020

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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12 December 2020

Primate models of movement disorders of basal ganglia origin

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12 December 2020

Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

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12 December 2020

Reversal of experimental parkinsonism by lesions of the subthalamic nucleus

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12 December 2020

Aminooxyacetic Acid Results in Excitotoxin Lesions by a Novel Indirect Mechanism

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12 December 2020

The calcium ion and cell death

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12 December 2020

Autoradiographic study of mitochondrial complex I and glutamate receptors in the basal ganglia of rats after unilateral subthalamic lesion.

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12 December 2020

Dopamine receptors in the basal ganglia: relevance to Parkinson's disease

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12 December 2020

Bilateral cerebral metabolic alterations following lesion of the ventromedial thalamic nucleus: mapping by the 14C-deoxyglucose method in conscious rats.

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12 December 2020

Organization of efferent projections of the subthalamic nucleus in the squirrel monkey as revealed by retrograde labeling methods.

1 reference

12 December 2020

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

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12 December 2020

Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons

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12 December 2020

NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum.

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12 December 2020

Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate

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12 December 2020

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12 December 2020

Does superoxide underlie the pathogenesis of hypertension?

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12 December 2020

Anatomical and chemical studies of a nigro-neostriatal projection in the cat.

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12 December 2020

Efferent projections of the subthalamic nucleus in the rat: light and electron microscopic analysis with the PHA-L method

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12 December 2020

Cytoskeletal alterations in human platelets exposed to oxidative stress are mediated by oxidative and Ca2+-dependent mechanisms

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12 December 2020

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

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12 December 2020

Increased nigral iron content in postmortem parkinsonian brain.

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12 December 2020

A family of AMPA-selective glutamate receptors

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12 December 2020

The neurotoxicity of iron and nitric oxide. Relevance to the etiology of Parkinson's disease.

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12 December 2020

Modulation of the N-methyl-D-aspartate channel by extracellular H+

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12 December 2020

Mitochondria and Na+/Ca2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons

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12 December 2020

Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicity.

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12 December 2020

Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?

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12 December 2020

The organization of the projection from the cerebral cortex to the striatum in the rat.

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12 December 2020

Anatomy and physiology of glutamate in the CNS.

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12 December 2020

Mitochondrial energy crisis in Parkinson's disease

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12 December 2020

Glutamate triggers internucleosomal DNA cleavage in neuronal cells

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12 December 2020

Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-Dopa in models of Parkinson's disease

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12 December 2020

Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats

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12 December 2020

The elusive transporters with a high affinity for glutamate

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12 December 2020

Lesion of the subthalamic nucleus for the alleviation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in the primate

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12 December 2020

Unaltered aconitase activity, but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson's disease.

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12 December 2020

Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP

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12 December 2020

Glutamate-dopamine interactions in the basal ganglia: relationship to Parkinson's disease

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12 December 2020

MPTP toxicity: implications for research in Parkinson's disease

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12 December 2020

Ca2+ permeability of KA-AMPA--gated glutamate receptor channels depends on subunit composition

1 reference

12 December 2020

Differential effect of subthalamic nucleus ablation on dopamine D1 and D2 agonist-induced rotation in 6-hydroxydopamine-lesioned rats.

1 reference

12 December 2020

The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons.

1 reference

12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

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12 December 2020

Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease

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12 December 2020

Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons

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12 December 2020

Noncompetitive excitatory amino acid receptor antagonists

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12 December 2020

Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing

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12 December 2020

Cytotoxic effects of acidic and sulphur containing amino acids on the infant mouse central nervous system

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12 December 2020

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

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12 December 2020

Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

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12 December 2020

Quantitative Autoradiography of Dihydrorotenone Binding to Complex I of the Electron Transport Chain

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12 December 2020

Iron and ferritin in substantia nigra in Parkinson's disease.

1 reference

12 December 2020

Calcium directly permeates kainate/alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid receptors in cultured cerebellar Purkinje neurons

1 reference

12 December 2020

Memantine displaces [3H]MK-801 at therapeutic concentrations in postmortem human frontal cortex

1 reference

12 December 2020

Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study

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12 December 2020

Glutamate: A Neurotransmitter in Mammalian Brain

1 reference

12 December 2020

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.

1 reference

12 December 2020

Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

Molecular cloning and characterization of the rat NMDA receptor

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12 December 2020

Interaction of 1-methyl-4-phenylpyridinium ion with human platelets

1 reference

12 December 2020

Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia

1 reference

12 December 2020

Excitatory influence of rat subthalamic nucleus to substantia nigra pars reticulata and the pallidal complex: electrophysiological data

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12 December 2020

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

1 reference

12 December 2020

Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients.

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12 December 2020

Effect of subthalamic nucleus lesion on mitochondrial enzyme activity in rat basal ganglia

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12 December 2020

Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells.

1 reference

12 December 2020

Regional variations in the pharmacology of NMDA receptor channel blockers: implications for therapeutic potential

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12 December 2020

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

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12 December 2020

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

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12 December 2020

Thalamic connectivity of rat somatic motor cortex.

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12 December 2020

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

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12 December 2020

Excitatory amino acid neurotoxicity and neurodegenerative disease

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12 December 2020

Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism.

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12 December 2020

Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation

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12 December 2020

Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate

1 reference

12 December 2020

Parkinson's disease: a disorder due to nigral glutathione deficiency?

1 reference

12 December 2020

The neostriatal mosaic: multiple levels of compartmental organization

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12 December 2020

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

1 reference

12 December 2020

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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12 December 2020

Platelets as a model for neurones?

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12 December 2020

Glutamate and the pathophysiology of hypoxic--ischemic brain damage

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12 December 2020

Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes

1 reference

12 December 2020

Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group

1 reference

12 December 2020

Modulation of the NMDA receptor by polyamines

1 reference

12 December 2020

Electrophysiology of dopamine-denervated striatal neurons. Implications for Parkinson's disease

1 reference

12 December 2020

The reaction sites of rotenone and ubiquinone with mitochondrial NADH dehydrogenase.

1 reference

12 December 2020

Glutamate-induced brain damage in infant primates

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12 December 2020

Polysynaptic regulation of glutamate receptors and mitochondrial enzyme activities in the basal ganglia of rats with unilateral dopamine depletion.

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12 December 2020

Glycine potentiates the NMDA response in cultured mouse brain neurons

1 reference

12 December 2020

Excitatory amino acid binding sites in the basal ganglia of the rat: A quantitative autoradiographic study

1 reference

12 December 2020

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

1 reference

12 December 2020

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

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12 December 2020

Cloning by functional expression of a member of the glutamate receptor family

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12 December 2020

Postmortem changes in mitochondrial respiratory enzymes in brain and a preliminary observation in Parkinson's disease.

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12 December 2020

The role of neuronal energy in the neurotoxicity of excitatory amino acids

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12 December 2020

The antiparkinsonian agent budipine is an N-methyl-D-aspartate antagonist.

1 reference

12 December 2020

A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra

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12 December 2020

Decreased glutamate uptake in subcortical areas deafferented by sensorimotor cortical ablation in the cat

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12 December 2020

Oxygen toxicity protecting enzymes in Parkinson's disease. Increase of superoxide dismutase-like activity in the substantia nigra and basal nucleus

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12 December 2020

N-methyl-D-aspartate-sensitive glutamate receptors induce calcium-mediated arachidonic acid release in primary cultures of cerebellar granule cells.

1 reference

12 December 2020

D-[3H]aspartate and [14C]GABA uptake in the basal ganglia of rats following lesions in the subthalamic region suggest a role for excitatory amino acid but not GABA-mediated transmission in subthalamic nucleus efferents.

1 reference

12 December 2020

Localization of striatal excitatory amino acid binding site subtypes to striatonigral projection neurons

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12 December 2020

Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes

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12 December 2020

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

1 reference

12 December 2020

Effect of parkinsonian signs and symptoms of bilateral subthalamic nucleus stimulation

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12 December 2020

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

1 reference

12 December 2020

Pargyline Prevents MPTP-Induced Parkinsonism in Primates

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12 December 2020

Molecular diversity of the NMDA receptor channel

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12 December 2020

Superoxide dismutases. An adaptation to a paramagnetic gas.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02740748

1 reference

PubMed ID

8732541

Dimensions Publication ID

26 September 2017

0 references

1 reference

PubMed ID

8732541