(Q41107151)

26 September 2017

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title

New antiherpesvirus agents. Their targets and therapeutic potential (English)

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26 September 2017

F A Alrabiah

1

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PubMed ID

8799682

26 September 2017

S L Sacks

series ordinal

2

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26 September 2017

1 July 1996

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26 September 2017

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26 September 2017

52

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26 September 2017

17-32

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26 September 2017

1

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https://scigraph.springernature.com/pub.10.2165/00003495-199652010-00002

26 September 2017

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cites work

Treatment of cytomegalovirus pneumonia

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12 December 2020

Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine

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12 December 2020

Antivirals for the treatment of herpesvirus infections

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12 December 2020

Pharmacokinetics of acyclovir after intravenous and oral administration.

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12 December 2020

The spectrum of antiviral activities of acyclovir in vitro and in vivo

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12 December 2020

Antiherpesviral and anticellular effects of 1-beta-D-arabinofuranosyl-E-5-(2-halogenovinyl) uracils

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12 December 2020

Comparative metabolism of E-5-(2-bromovinyl)-2'-deoxyuridine and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil in herpes simplex virus-infected cells

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12 December 2020

Antiviral activity of phosphonylmethoxyalkyl derivatives of purine and pyrimidines

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12 December 2020

Famciclovir for the treatment of acute herpes zoster: effects on acute disease and postherpetic neuralgia. A randomized, double-blind, placebo-controlled trial. Collaborative Famciclovir Herpes Zoster Study Group

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12 December 2020

Acyclovir: discovery, mechanism of action, and selectivity

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12 December 2020

Foscarnet. A review of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis

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12 December 2020

Ganciclovir. An update of its therapeutic use in cytomegalovirus infection

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12 December 2020

Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus

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12 December 2020

Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs

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12 December 2020

Human pharmacokinetics and tolerance of oral ganciclovir

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12 December 2020

Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation

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12 December 2020

Ganciclovir treatment of life- or sight-threatening cytomegalovirus infection: experience in 314 immunocompromised patients

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12 December 2020

(S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine (cidofovir): results of a phase I/II study of a novel antiviral nucleotide analogue

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12 December 2020

Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections

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12 December 2020

Management of cytomegalovirus disease with antiviral drugs

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12 December 2020

Evaluation of bromovinyldeoxyuridine-related compounds in the treatment of experimental herpes simplex keratitis

1 reference

12 December 2020

Investigation of antiviral activity of 1-β-d-arabinofuranosylthymine (ara-T) and 1-β-d-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-ara-U) in monkeys infected with simian varicella virus

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12 December 2020

A novel selective broad-spectrum anti-DNA virus agent

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12 December 2020

Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region

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12 December 2020

Treatment of cytomegalovirus retinitis with ganciclovir

1 reference

12 December 2020

In vitro susceptibility of cytomegalovirus isolates from immunocompromised patients to acyclovir and ganciclovir.

1 reference

12 December 2020

Evaluation of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil (BrVaraU, VaraU) in the treatment of experimental herpes simplex virus type 1 keratitis in rabbits: comparison with (E)-5-(2-bromovinyl)-2'-deoxyuridine (BrVUdR).

1 reference

12 December 2020

Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex

1 reference

12 December 2020

Inhibitory effects of acyclic nucleoside phosphonate analogs, including (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, on Epstein-Barr virus replication

1 reference

12 December 2020

Pharmacokinetics of the acyclovir pro-drug valaciclovir after escalating single- and multiple-dose administration to normal volunteers

1 reference

12 December 2020

Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus types 1 and 2

1 reference

12 December 2020

A double-blind clinical study in patients with herpes zoster to establish YN-72 (Brovavir) dose

1 reference

12 December 2020

Analysis of toxic and mutagenic activities of antiherpesvirus nucleosides against HeLa cells and herpes simplex virus type 1

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12 December 2020

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice

1 reference

12 December 2020

Oral ganciclovir approved

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12 December 2020

Differential activity of potential antiviral nucleoside analogs on herpes simplex virus-induced and human cellular thymidine kinases

1 reference

12 December 2020

Aciclovir. A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic efficacy

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12 December 2020

Oral ganciclovir as maintenance treatment for cytomegalovirus retinitis in patients with AIDS. Syntex Cooperative Oral Ganciclovir Study Group

1 reference

12 December 2020

Clinical pharmacokinetics of acyclovir

1 reference

12 December 2020

Brovavir: its antiherpesviral activity and mode of action

1 reference

12 December 2020

Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice

1 reference

12 December 2020

Clinical effect of BV-araU on varicella-zoster virus infection in immunocompromised patients with haematological malignancies

1 reference

12 December 2020

Use of ganciclovir to treat serious cytomegalovirus infections in patients with AIDS

1 reference

12 December 2020

Resistance of herpesviruses to antiviral drugs

1 reference

12 December 2020

Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo

1 reference

12 December 2020

The disposition of acyclovir in different species

1 reference

12 December 2020

Ganciclovir treatment of cytomegalovirus disease in transplant recipients and other immunocompromised hosts

1 reference

12 December 2020

Famciclovir for herpes zoster

1 reference

12 December 2020

n-docosanol: broad spectrum anti-viral activity against lipid-enveloped viruses

1 reference

12 December 2020

Ganciclovir for the treatment and suppression of serious infections caused by cytomegalovirus

1 reference

12 December 2020

Treatment of serious cytomegalovirus infections with 9-(1,3-dihydroxy-2-propoxymethyl)guanine in patients with AIDS and other immunodeficiencies

1 reference

12 December 2020

A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells

1 reference

12 December 2020

Phosphorylation of the antiviral precursor 9-(1,3-dihydroxy-2-propoxymethyl)guanine monophosphate by guanylate kinase isozymes

1 reference

12 December 2020

Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogs

1 reference

12 December 2020

Antiherpesvirus activity of 9-(4-hydroxy-3-hydroxy-methylbut-1-yl)guanine (BRL 39123) in cell culture

1 reference

12 December 2020

Effect of (E)-5-(2-bromovinyl)uracil on the catabolism and antitumor activity of 5-fluorouracil in rats and leukemic mice.

1 reference

12 December 2020

Treatment of varicella in the immunocompetent adult

1 reference

12 December 2020

Oral brivudin vs. intravenous acyclovir in the treatment of herpes zoster in immunocompromised patients: a randomized double-blind trial

1 reference

12 December 2020

Pharmacokinetic, safety, and antiviral profiles of oral ganciclovir in persons infected with human immunodeficiency virus: a phase I/II study. AIDS Clinical Trials Group, and Cytomegalovirus Cooperative Study Group

1 reference

12 December 2020

Safety of famciclovir in patients with herpes zoster and genital herpes

1 reference

12 December 2020

Intracellular metabolism of the antiherpes agent (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine

1 reference

12 December 2020

9-(2-Hydroxyethoxymethyl)guanine activity against viruses of the herpes group

1 reference

12 December 2020

Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir

1 reference

12 December 2020

Sensitivity of clinical isolates of human cytomegalovirus to 9-(1,3-dihydroxy-2-propoxymethyl)guanine

1 reference

12 December 2020

Current management of cytomegalovirus disease in patients with AIDS.

1 reference

12 December 2020

Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and E-5-(2-bromovinyl)-2'-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication

1 reference

12 December 2020

Ganciclovir treatment of gastrointestinal infections caused by cytomegalovirus in patients with AIDS

1 reference

12 December 2020

Inhibition of herpes simplex virus type 1 DNA polymerase by [1R(1 alpha,2 beta,3 alpha)]-9-[2,3-bis(hydroxymethyl)cyclobutyl] guanine

1 reference

12 December 2020

Evaluation of SQ 34,514: pharmacokinetics and efficacy in experimental herpesvirus infections in mice

1 reference

12 December 2020

Drug susceptibilities of isolates of varicella-zoster virus in a clinical study of oral brovavir

1 reference

12 December 2020

Ganciclovir for treatment of renal transplant-associated primary cytomegalovirus pneumonia

1 reference

12 December 2020

Effects of phosphonylmethoxyalkyl-purine and -pyrimidine derivatives on TK+ and TK- HSV-1 keratitis in rabbits

1 reference

12 December 2020

Antiviral activity and pharmacokinetics of HOE 602, an acyclic nucleoside, in animal models

1 reference

12 December 2020

Evaluation of infrequent dosing regimens with (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine (S-HPMPC) on simian varicella infection in monkeys

1 reference

12 December 2020

A Randomized, Placebo-Controlled Trial of Oral Acyclovir for the Prevention of Cytomegalovirus Disease in Recipients of Renal Allografts

1 reference

12 December 2020

Acyclovir--and beyond

1 reference

12 December 2020

In vitro and in vivo antiviral activity of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) and related compounds

1 reference

12 December 2020

Famciclovir, a new oral antiherpes drug: results of the first controlled clinical study demonstrating its efficacy and safety in the treatment of uncomplicated herpes zoster in immunocompetent patients

1 reference

12 December 2020

Intravenous versus oral ganciclovir: European/Australian comparative study of efficacy and safety in the prevention of cytomegalovirus retinitis recurrence in patients with AIDS. The Oral Ganciclovir European and Australian Cooperative Study Group

1 reference

12 December 2020

(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication

1 reference

12 December 2020

Treatment of cytomegalovirus retinitis in patients with AIDS.

1 reference

12 December 2020

Prodrugs of the selective antiherpesvirus agent 9-[4-hydroxy-3-(hydroxymethyl)but-1-yl]guanine (BRL 39123) with improved gastrointestinal absorption properties

1 reference

12 December 2020

10.2165/00003495-199652010-00002

Identifiers

DOI

1 reference

PubMed ID

8799682

Dimensions Publication ID

26 September 2017

0 references

1 reference

PubMed ID

8799682