(Q41132341)

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Using an RNAi Signature Assay To Guide the Design of Three-Drug-Conjugated Nanoparticles with Validated Mechanisms, In Vivo Efficacy, and Low Toxicity

scientific article published on 14 September 2016

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scholarly article

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23 March 2020

Using an RNAi Signature Assay To Guide the Design of Three-Drug-Conjugated Nanoparticles with Validated Mechanisms, In Vivo Efficacy, and Low Toxicity (English)

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23 March 2020

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23 March 2020

Hung V-T Nguyen

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23 March 2020

Jeremiah A Johnson

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23 March 2020

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Jonathan C Barnes

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23 March 2020

Longyan Liao

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23 March 2020

Jenny Liu

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23 March 2020

Michael T Hemann

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23 March 2020

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14 September 2016

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23 March 2020

Journal of the American Chemical Society

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23 March 2020

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23 March 2020

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23 March 2020

12494-12501

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Nanoparticles for combination drug therapy

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Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment

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Brush-first and click: efficient synthesis of nanoparticles that degrade and release doxorubicin in response to light.

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Bidentate ligands on osmium(VI) nitrido complexes control intracellular targeting and cell death pathways

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Folate conjugation to polymeric micelles via boronic acid ester to deliver platinum drugs to ovarian cancer cell lines

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Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo

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Predicting cancer drug mechanisms of action using molecular network signatures

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Defining principles of combination drug mechanisms of action

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The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

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Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.

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Synthesis, characterization and antiproliferative activity on mesothelioma cell lines of bis(carboxylato)platinum(IV) complexes based on picoplatin.

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Nanoparticle-based combination therapy toward overcoming drug resistance in cancer

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Anticancer platinum (IV) prodrugs with novel modes of activity.

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Nanoparticle PEGylation for imaging and therapy

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive detection of DNA modifications induced by cisplatin and carboplatin in vitro and in vivo using a monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/27626288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dependence of the Reduction Products of Platinum(IV) Prodrugs upon the Configuration of the Substrate, Bulk of the Carrier Ligands, and Nature of the Reducing Agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/27626288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platinum(iv) anticancer prodrugs - hypotheses and facts

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fate of platinum(II) and platinum(IV) anti-cancer agents in cancer cells and tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/27626288

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JACS.6B06321

1 reference

Europe PubMed Central

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23 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27626288%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27626288%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

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