(Q41136793)

English

The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ in human leukaemia and colorectal carcinoma cell lines

scientific article published on January 1997

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Statements

scholarly article

1 reference

Europe PubMed Central

27 September 2017

The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ in human leukaemia and colorectal carcinoma cell lines (English)

1 reference

Europe PubMed Central

27 September 2017

colorectal carcinoma

1 reference

based on heuristic

inferred from title

author name string

Estlin EJ

1

1 reference

Europe PubMed Central

27 September 2017

Balmanno K

2

1 reference

Europe PubMed Central

27 September 2017

Calvert AH

3

1 reference

Europe PubMed Central

27 September 2017

Hall AG

4

1 reference

Europe PubMed Central

27 September 2017

Lunec J

5

1 reference

Europe PubMed Central

27 September 2017

Newell DR

6

1 reference

Europe PubMed Central

27 September 2017

Pearson AD

7

1 reference

Europe PubMed Central

27 September 2017

Taylor GA

8

1 reference

Europe PubMed Central

27 September 2017

language of work or name

0 references

publication date

1 January 1997

1 reference

Europe PubMed Central

27 September 2017

British Journal of Cancer

1 reference

Europe PubMed Central

27 September 2017

76

1 reference

Europe PubMed Central

27 September 2017

12

1 reference

Europe PubMed Central

27 September 2017

1579-1585

1 reference

Europe PubMed Central

27 September 2017

https://scigraph.springernature.com/pub.10.1038/bjc.1997.600

0 references

Folate-based thymidylate synthase inhibitors as anticancer drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

Molecular characterisation of two cell lines selected for resistance to the folate-based thymidylate synthase inhibitor, ZD1694.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

Fluorouracil: biochemistry and pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

Variations in patterns of DNA damage induced in human colorectal tumor cells by 5-fluorodeoxyuridine: implications for mechanisms of resistance and cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

27 September 2017

Quantitation of thymidylate synthase in human tumors using an ultrasensitive enzyme-linked immunoassay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

Evaluation of immunohistochemical staining and activity of thymidylate synthase in cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

Molecular cloning of DNA sequences complementary to mouse thymidylate synthase messenger RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

A naturally occurring variation in thymidylate synthase structure is associated with a reduced response to 5-fluoro-2'-deoxyuridine in a human colon tumor cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

Sensitivity of human, murine, and rat cells to 5-fluorouracil and 5'-deoxy-5-fluorouridine in relation to drug-metabolizing enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

Human lymphoblastoid cells with acquired resistance to C2-desamino-C2-methyl-N10-propargyl-5,8-dideazafolic acid: a novel folate-based thymidylate synthase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

A naturally occurring tyrosine to histidine replacement at residue 33 of human thymidylate synthase confers resistance to 5-fluoro-2'-deoxyuridine in mammalian and bacterial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

14 June 2018

Design of thymidylate synthase inhibitors using protein crystal structures: the synthesis and biological evaluation of a novel class of 5-substituted quinazolinones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

19 August 2018

The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

19 August 2018

Acquisition of resistance to antifolates caused by enhanced gamma-glutamyl hydrolase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2228199

19 August 2018

Quinazoline antifolates with dual biochemical loci of action. Biochemical and biological studies directed towards overcoming methotrexate resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/9413945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9413945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase as a determinant of 5-fluoro-2'-deoxyuridine response in human colonic tumor cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9413945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9413945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase from untreated human colorectal cancer and colonic mucosa: Enzyme activity and inhibition by 5-fluoro-2′-deoxyuridine-5′-monophosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9413945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9413945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AG337, a novel lipophilic thymidylate synthase inhibitor: in vitro and in vivo preclinical studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9413945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJC.1997.600

1 reference

Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

27 September 2017

1 reference

Europe PubMed Central

27 September 2017

ResearchGate publication ID

0 references

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