(Q41143946)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

review article

1 reference

title

Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

4

J S Harmatz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

2

D J Greenblatt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

5

R I Shader

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1

L L von Moltke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

author name string

J Schmider

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

publication date

1 January 1995

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacokinetics

20 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

volume

29 Suppl 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

page(s)

33-43; discussion 43-4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8846621%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.2165/00003088-199500291-00007

20 October 2019

exact match

0 references

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Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450.

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Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins

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12 December 2020

Population study of triazolam pharmacokinetics

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12 December 2020

Gender differences in pharmacokinetics and pharmacodynamics of psychotropic medication

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12 December 2020

Frequency distribution of dapsone N-hydroxylase, a putative probe for P4503A4 activity, in a white population

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12 December 2020

Modulation of rabbit and human hepatic cytochrome P-450-catalyzed steroid hydroxylations by alpha-naphthoflavone

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12 December 2020

The expression of xenobiotic-metabolizing cytochromes P450 in fetal tissues

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12 December 2020

Pharmacokinetics and pharmacodynamics of alprazolam after oral and IV administration

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12 December 2020

Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta

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Effect of age, gender, and obesity on midazolam kinetics.

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N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors

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12 December 2020

P450 3A activity and cyclosporine dosing in kidney and heart transplant recipients

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The rational selection of drug interaction studies: implications of recent advances in drug metabolism.

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Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver

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Metabolism of cytochrome P4503A substrates in vivo administered by the same route: lack of correlation between alfentanil clearance and erythromycin breath test.

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No evidence of a genetic polymorphism in the oxidative metabolism of midazolam.

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12 December 2020

Effect of ranitidine on the disposition of orally and intravenously administered triazolam

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12 December 2020

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes

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12 December 2020

The human hepatic cytochromes P450 involved in drug metabolism

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12 December 2020

Cytochrome P450 in human fetal liver: significance and fetal-specific expression

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12 December 2020

Expression of human cytochrome P450 enzymes in yeast and bacteria and relevance to studies on catalytic specificity.

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12 December 2020

Meanings of Ki for conventional and alternate-substrate inhibitors.

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12 December 2020

Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site.

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12 December 2020

Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity

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12 December 2020

Pharmacokinetic pharmacodynamic evaluation of the combined administration of alprazolam and fluoxetine.

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12 December 2020

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

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12 December 2020

Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo

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12 December 2020

Grapefruit juice and drugs. How significant is the interaction?

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12 December 2020

Human cytochromes P450: problems and prospects

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12 December 2020

Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly. Therapeutic considerations (Part I).

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12 December 2020

Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals

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12 December 2020

Drug metabolism by cytochromes P450 in the liver and small bowel.

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12 December 2020

A pharmacokinetic and pharmacodynamic evaluation of the combined administration of alprazolam and fluvoxamine.

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12 December 2020

Cytochrome P450 and monoclonal antibodies.

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12 December 2020

Triazolam pharmacokinetics after intravenous, oral, and sublingual administration

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12 December 2020

Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation

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12 December 2020

The erythromycin breath test selectively measures P450IIIA in patients with severe liver disease

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12 December 2020

Comparison of alprazolam plasma levels in normal Asian and Caucasian male volunteers

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12 December 2020

In vitro approaches can predict human drug metabolism

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12 December 2020

Comparative pharmacokinetics of alprazolam and lorazepam in humans and in African Green Monkeys

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12 December 2020

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

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12 December 2020

Noninvasive tests of CYP3A enzymes

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12 December 2020

Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants

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12 December 2020

Kinetic and dynamic components of increased benzodiazepine sensitivity in aging animals

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12 December 2020

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

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12 December 2020

Metabolism of terfenadine associated with CYP3A(4) activity in human hepatic microsomes

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12 December 2020

Inhibitors of alprazolam metabolism in vitro: effect of serotonin-reuptake-inhibitor antidepressants, ketoconazole and quinidine

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12 December 2020

Potential terfenadine-fluoxetine interaction

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12 December 2020

Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men

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12 December 2020

Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes

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12 December 2020

Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions

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12 December 2020

Small Intestinal Cytochromes P450

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12 December 2020

Fluoxetine impairs clearance of alprazolam but not of clonazepam

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12 December 2020

Drug metabolism in extrahepatic diseases

1 reference

12 December 2020