(Q41173924)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

ChEBI release 2020-05-28

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

6

Christopher G Mowat

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Igor Efimov

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Jaswir Basran

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Xiao Sun

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Nishma Chauhan

4

1 reference

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21 January 2020

Stephen K Chapman

5

1 reference

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21 January 2020

language of work or name

English

0 references

publication date

2 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

Journal of the American Chemical Society

21 January 2020

published in

1 reference

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21 January 2020

volume

134

1 reference

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21 January 2020

issue

6

1 reference

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21 January 2020

page(s)

3034-3041

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons.

21 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Substrate stereo-specificity in tryptophan dioxygenase and indoleamine 2,3-dioxygenase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Rational design of indoleamine 2,3-dioxygenase inhibitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Evidence for a ferryl intermediate in a heme-based dioxygenase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Inhibitory substrate binding site of human indoleamine 2,3-dioxygenase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Nature of the Fe-O2 bonding in oxy-myoglobin: effect of the protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2,3-dioxygenase (IDO), a novel target in cancer disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Molecular insights into substrate recognition and catalysis by tryptophan 2,3-dioxygenase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Redox and spectroscopic properties of human indoleamine 2,3-dioxygenase and a His303Ala variant: implications for catalysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Indoleamine 2,3-dioxygenase. Purification and some properties

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Spectroscopic studies of ligand and substrate binding to human indoleamine 2,3-dioxygenase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Probing the ternary complexes of indoleamine and tryptophan 2,3-dioxygenases by cryoreduction EPR and ENDOR spectroscopy

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Substrate-protein interaction in human tryptophan dioxygenase: the critical role of H76.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Tryptophan pyrrolase of rabbit intestine. D- and L-tryptophan-cleaving enzyme or enzymes.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Ligand and substrate migration in human indoleamine 2,3-dioxygenase

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

The role of serine 167 in human indoleamine 2,3-dioxygenase: a comparison with tryptophan 2,3-dioxygenase

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Tryptophan and glucose metabolism in rat liver cells. The effects of DL-6-chlorotryptophan, 4-chloro-3-hydroxyanthranilate and pyrazinamide

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280726

Indoleamine 2,3-dioxygenase. Equilibrium studies of the tryptophan binding to the ferric, ferrous, and CO-bound enzymes

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22299628

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Acid-alkaline transition and thermal spin equilibrium of the heme in ferric L-tryptophan 2,3-dioxygenases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22299628

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JA208694G

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

22299628

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22299628%20AND%20SRC:MED&resulttype=core&format=json