(Q41175238)

English

Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease

scientific article published on August 1996

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

Huntington's disease

0 references

1 reference

based on heuristic

inferred from title

Jeffrey H Kordower

6

object named as

J H Kordower

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

author name string

D F Emerich

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

M D Lindner

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

S R Winn

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

E Y Chen

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

B R Frydel

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

language of work or name

0 references

publication date

1 August 1996

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

16

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

16

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

5168-5181

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

Differential loss of striatal projection neurons in Huntington disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of neurotrophic factor protection against calcium- and free radical-mediated excitotoxic injury: implications for treating neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Body weight and dietary factors in Huntington's disease patients compared with matched controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete nucleotide and deduced amino acid sequence of bovine phenylethanolamine N-methyltransferase: partial amino acid homology with rat tyrosine hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor prevents retrograde neuronal death in the adult central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transplantation of a polymer-encapsulated cell line genetically engineered to release NGF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of intraventricular encapsulated hNGF-secreting fibroblasts in aged rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal grafts provide sustained protection from kainic and quinolinic acid-induced damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The therapeutic potential of neurotrophic factors in the treatment of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of biologically delivered NGF, BDNF and bFGF on striatal excitotoxic lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of embryonic motoneuron survival in vivo by ciliary neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurotoxicity of excitatory amino acids is produced by passive chloride influx.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: involvement of the glutathione system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal degeneration induced by mitochondrial blockade is prevented by biologically delivered NGF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of NGF in sympathetic neurons leads to excessive axon outgrowth from ganglia but decreased terminal innervation within tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor prevents neuronal degeneration and promotes low affinity NGF receptor expression in the adult rat CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short- and long-term survival of large neurons in the excitotoxic lesioned rat caudate nucleus: a light and electron microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The quinolinic acid model of Huntington's disease: locomotor abnormalities

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of nerve growth factor on cholinergic brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative excitotoxic hypotheses

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification, cloning, and expression of ciliary neurotrophic factor (CNTF).

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in basal ganglia and substantia nigra substance P levels in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical pathology of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic gene transfer of nerve growth factor promotes the survival of axotomized septal neurons and the regeneration of their axons in adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal tissue transplants attenuate apomorphine-induced rotational behavior in rats with unilateral kainic acid lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymer-encapsulated PC12 cells promote recovery of motor function in aged rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor maintains motoneurons and their target muscles in developing rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apomorphine-induced dyskinesias after excitotoxic caudate-putamen lesions and the effects of neural transplantation in non-human primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a defect in NADH: ubiquinone oxidoreductase (complex I) in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymer-encapsulated cells genetically modified to secrete human nerve growth factor promote the survival of axotomized septal cholinergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combining CNS transplantation and gene transfer

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grafting genetically modified cells to the brain: possibilities for the future

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human beta nerve growth factor obtained from a baculovirus expression system has potent in vitro and in vivo neurotrophic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrastriatal implants of polymer encapsulated cells genetically modified to secrete human nerve growth factor: trophic effects upon cholinergic and noncholinergic striatal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory amino acids and neuropsychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebral grafting of cultured autologous skin fibroblasts into the rat striatum: an assessment of graft size and ultrastructure

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor prevents degeneration of adult rat substantia nigra dopaminergic neurons in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is activation of the Na+K+ pump necessary for NGF-mediated neuronal survival?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinic acid lesion of the striatum induces impairment in spatial learning and motor performance in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatostatin and neuropeptide Y concentrations in pathologically graded cases of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebral implantation of nerve growth factor-producing fibroblasts protects striatum against neurotoxic levels of excitatory amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implantation of polymer-encapsulated human nerve growth factor-secreting fibroblasts attenuates the behavioral and neuropathological consequences of quinolinic acid injections into rodent striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Female rats are more sensitive to the locomotor alterations following quinolinic acid-induced striatal lesions: Effects of striatal transplants

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel approach to neural transplantation in Parkinson's disease: use of polymer-encapsulated cell therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of administration of ciliary neurotrophic factor on normal motor and sensory peripheral nerves in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A primate model of Huntington's disease: cross-species implantation of striatal precursor cells to the excitotoxically lesioned baboon caudate-putamen

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate neurotoxicity and diseases of the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the CNTF gene results in motor neuron degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.16-16-05168.1996

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579299&resulttype=core&format=json

15 May 2020

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