(Q41176248)

27 September 2017

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title

The role of p53 in cell cycle regulation (English)

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27 September 2017

Shaw PH

1

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27 September 2017

1 July 1996

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Pathology, Research and Practice

27 September 2017

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27 September 2017

192

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27 September 2017

669-675

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27 September 2017

7

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Mammalian DNA nucleotide excision repair reconstituted with purified protein components.

27 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Oncogenes in Melanomas

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Gene regulation by temperature-sensitive p53 mutants: identification of p53 response genes

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Morphologic transformation of the C3H 10T1/2 cell line is accompanied by altered expression of the p53 tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Definition of a consensus binding site for p53

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Wild-type p53 activates transcription in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Presence of a potent transcription activating sequence in the p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

A transcriptionally active DNA-binding site for human p53 protein complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Wild-type p53 can down-modulate the activity of various promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Tumor suppressor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

1 reference

7 January 2021

Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Germline p16 mutations in familial melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

T antigen is bound to a host protein in SY40-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Cell cycle control of morphogenesis in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Isolation and characterization of a human p53 cDNA clone: expression of the human p53 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

p53-dependent and p53-independent activation of apoptosis in mammary epithelial cells reveals a survival function of EGF and insulin.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

A family of human cdc2-related protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Targets of cyclin-dependent protein kinases.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Mutations in the p53 gene occur in diverse human tumour types

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Universal control mechanism regulating onset of M-phase

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

The role of p34 kinases in the G1 to S-phase transition

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Mammalian p53 can function as a transcription factor in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

1 reference

7 January 2021

Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision-repair

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Human breast cancer: frequent p53 allele loss and protein overexpression

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

p53 tagged sites from human genomic DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

p53 domains: identification and characterization of two autonomous DNA-binding regions.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Effect of tumor suppressors on cell cycle-regulatory genes: RB suppresses p34cdc2 expression and normal p53 suppresses cyclin A expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

p53-mediated cell death: relationship to cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0344-0338%2896%2980088-4

7 January 2021

10.1016/S0344-0338(96)80088-4

Identifiers

DOI

0 references

PubMed ID

8880867

1 reference

PubMed ID

8880867