(Q41177250)

English

Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1.

scientific article published on 29 September 2008

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1. (English)

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Borrelia burgdorferi

0 references

1 reference

based on heuristic

inferred from title

9

object named as

Peter F Zipfel

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Christine Skerka

4

object named as

Christine Skerka

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

10

object named as

Peter Kraiczy

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

5

object named as

Volker Brade

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

1

object named as

Corinna Siegel

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

3

object named as

Katrin Haupt

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

author name string

Johanna Schreiber

2

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Markus M Simon

6

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Brian Stevenson

7

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Reinhard Wallich

8

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

language of work or name

0 references

publication date

29 September 2008

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

283

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

50

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

34855-34863

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Identification of an antiparallel coiled-coil/loop domain required for ligand binding by the Borrelia hermsii FhbA protein: additional evidence for the role of FhbA in the host-pathogen interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Complement evasion by human pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Borrelia burgdorferi complement regulator-acquiring surface proteins (BbCRASPs): Expression patterns during the mammal-tick infection cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Borrelia burgdorferi complement regulator-acquiring surface protein 2 (CspZ) as a serological marker of human Lyme disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Immune evasion of the human pathogen Pseudomonas aeruginosa: elongation factor Tuf is a factor H and plasminogen binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Tick–host–pathogen interactions in Lyme borreliosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Human pathogenic Borrelia spielmanii sp. nov. resists complement-mediated killing by direct binding of immune regulators factor H and factor H-like protein 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Coordinated expression of Borrelia burgdorferi complement regulator-acquiring surface proteins during the Lyme disease spirochete's mammal-tick infection cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Dual binding specificity of a Borrelia hermsii-associated complement regulator-acquiring surface protein for factor H and plasminogen discloses a putative virulence factor of relapsing fever spirochetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Evolving models of Lyme disease spirochete gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

LfhA, a novel factor H-binding protein of Leptospira interrogans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Molecular analyses of the interaction of Borrelia hermsii FhbA with the complement regulatory proteins factor H and factor H-like protein 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Borrelia burgdorferi regulates expression of complement regulator-acquiring surface protein 1 during the mammal-tick infection cycle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Complement escape of human pathogenic bacteria by acquisition of complement regulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Survival strategies of Borrelia burgdorferi, the etiologic agent of Lyme disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Temporal analysis of Borrelia burgdorferi Erp protein expression throughout the mammal-tick infectious cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

aadA confers streptomycin resistance in Borrelia burgdorferi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Analysis of the ability of spirochete species associated with relapsing fever, avian borreliosis, and epizootic bovine abortion to bind factor H and cleave c3b.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Host association of Borrelia burgdorferi sensu lato--the key role of host complement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Differential binding of host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: a possible mechanism underlying the expansive host range of Lyme disease spirochetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Further characterization of complement regulator-acquiring surface proteins of Borrelia burgdorferi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Complement evasion by Borrelia burgdorferi: serum-resistant strains promote C3b inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

The contrasting mechanisms of serum resistance of Neisseria gonorrhoeae and group B Neisseria meningitidis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Validity of interpretation criteria for standardized Western blots (immunoblots) for serodiagnosis of Lyme borreliosis based on sera collected throughout Europe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

FHL-1/reconectin: a human complement and immune regulator with cell-adhesive function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

The C-terminus of factor H: monoclonal antibodies inhibit heparin binding and identify epitopes common to factor H and factor H-related proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Serum complement sensitivity as a key factor in Lyme disease ecology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Complement-mediated serum sensitivity among spirochetes that cause Lyme disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Mapping of the domains required for decay acceleration activity of the human factor H-like protein 1 and factor H.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Protein-protein interactions: methods for detection and analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

The baculovirus expression vector pBSV-8His directs secretion of histidine-tagged proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Mapping of the complement regulatory domains in the human factor H-like protein 1 and in factor H1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Dominant forces in protein folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Differences of two Borrelia burgdorferi strains in complement activation and serum resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

27 September 2017

Delineation of species-specific binding properties of the CspZ protein (BBH06) of Lyme disease spirochetes: evidence for new contributions to the pathogenesis of Borrelia spp.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

17 June 2018

Identification and functional characterization of complement regulator-acquiring surface protein 1 of the Lyme disease spirochetes Borrelia afzelii and Borrelia garinii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

17 June 2018

Complement regulator-acquiring surface protein 1 imparts resistance to human serum in Borrelia burgdorferi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

A novel fold for the factor H-binding protein BbCRASP-1 of Borrelia burgdorferi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

Lysine-dependent multipoint binding of the Borrelia burgdorferi virulence factor outer surface protein E to the C terminus of factor H.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

The group B streptococcal beta and pneumococcal Hic proteins are structurally related immune evasion molecules that bind the complement inhibitor factor H in an analogous fashion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

Complement Resistance of Borrelia burgdorferi Correlates with the Expression of BbCRASP-1, a Novel Linear Plasmid-encoded Surface Protein That Interacts with Human Factor H and FHL-1 and Is Unrelated to Erp Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

A common site within factor H SCR 7 responsible for binding heparin, C-reactive protein and streptococcal M protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

Streptococcus pneumoniae evades complement attack and opsonophagocytosis by expressing the pspC locus-encoded Hic protein that binds to short consensus repeats 8-11 of factor H.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

Comparison of two laboratory methods for the determination of serum resistance in Borrelia burgdorferi isolates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596382

19 August 2018

Heterogeneity in the complement-dependent bacteriolysis within the species of Borrelia burgdorferi

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a domain in human factor H and factor H-like protein-1 required for the interaction with streptococcal M proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the hypervariable region in streptococcal M proteins: binding of a human complement inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Borrelia burgdorferi erp genes are expressed at different levels within tissues of chronically infected mammalian hosts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptococcus pneumoniae recruits complement factor H through the amino terminus of CbpA

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of BbCRASP-2, a distinct outer membrane protein of Borrelia burgdorferi that binds host complement regulators factor H and FHL-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The host immune regulator factor H interacts via two contact sites with the PspC protein of Streptococcus pneumoniae and mediates adhesion to host epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and Factor H

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor H

1 reference

https://pubmed.ncbi.nlm.nih.gov/18824548

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M805844200

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q41177250&oldid=1859524662"