(Q41183905)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Patrick J Pollard

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Nicholas A. Wright

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

13

Ian Tomlinson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

author name string

Stefania Segditsas

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Maesha Deheragoda

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Rosemary Jeffery

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Emma Nye

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Helen Lockstone

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Hayley Davis

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Susan Clark

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Gordon Stamp

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Richard Poulsom

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

language of work or name

English

0 references

publication date

6 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

volume

59

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

page(s)

1680-1686

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

15 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3002835/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3002835

inferred from PubMed Central ID database lookup

cites work

Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Crypt stem cells as the cells-of-origin of intestinal cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Bone morphogenetic protein signalling in colorectal cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Bmi1 is expressed in vivo in intestinal stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Eph-ephrin signalling in adult tissues and cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Identification of stem cells in small intestine and colon by marker gene Lgr5

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Phenotypic characterization of human colorectal cancer stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Myc deletion rescues Apc deficiency in the small intestine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Gastrointestinal stem cells and cancer: bridging the molecular gap.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Identification and expansion of human colon-cancer-initiating cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Neonatal lethality of LGR5 null mice is associated with ankyloglossia and gastrointestinal distension

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Cloning and characterization of the promoter of human Wnt inhibitory factor-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Identification of a putative intestinal stem cell and early lineage marker; musashi-1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Clonality and life cycles of intestinal crypts explained by a state dependent stochastic model of epithelial stem cell organization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Failure of programmed cell death and differentiation as causes of tumors: some simple mathematical models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3002835

A robust method for isotopic riboprobe in situ hybridisation to localise mRNAs in routine pathology specimens

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20926645

12 December 2020

inferred from PubMed ID database lookup

Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20926645

12 December 2020

inferred from PubMed ID database lookup

Matrix metalloproteinase matrilysin (MMP-7) participates in the progression of human gastric and esophageal cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20926645

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1136/GUT.2009.193680

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20926645%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference