(Q41197203)

28 September 2017

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title

Vitamin C: antioxidant or pro-oxidant in vivo? (English)

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28 September 2017

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Halliwell B

1

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28 September 2017

publication date

1 November 1996

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28 September 2017

published in

Free Radical Research

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28 September 2017

volume

25

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28 September 2017

issue

5

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28 September 2017

page(s)

439-454

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Ascorbate is an outstanding antioxidant in human blood plasma

28 September 2017

cites work

1 reference

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Biokinetics of dietary RRR-alpha-tocopherol in the male guinea pig at three dietary levels of vitamin C and two levels of vitamin E. Evidence that vitamin C does not "spare" vitamin E in vivo

21 January 2018

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Direct observation of a free radical interaction between vitamin E and vitamin C

21 January 2018

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Reaction of ascorbate with the alpha-tocopheroxyl radical in micellar and bilayer membrane systems

21 January 2018

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The protection by ascorbate and glutathione against microsomal lipid peroxidation is dependent on vitamin E.

21 January 2018

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The cooperative action of vitamins E and C in the protection against peroxidation of parinaric acid in human erythrocyte membranes

21 January 2018

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How to characterize a biological antioxidant

21 January 2018

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Antioxidant protection against organic and inorganic oxygen radicals by normal human plasma: the important primary role for iron-binding and iron-oxidising proteins

21 January 2018

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The antioxidants of human extracellular fluids

21 January 2018

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Interaction of nitrogen dioxide with human plasma. Antioxidant depletion and oxidative damage

21 January 2018

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Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Protective effects of ascorbic acid

21 January 2018

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Modification of plasma proteins by cigarette smoke as measured by protein carbonyl formation

21 January 2018

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Carcinogenic antioxidants. Diethylstilboestrol, hexoestrol and 17 alpha-ethynyloestradiol.

21 January 2018

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Some properties of the ascorbate free radical

21 January 2018

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The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate

21 January 2018

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Ascorbic acid, metal ions and the superoxide radical

21 January 2018

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Oxidation of ascorbic acid with superoxide anion generated by the xanthine-xanthine oxidase system

21 January 2018

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ESR investigations of the reactions of radiation-produced thiyl and DNA peroxyl radicals: formation of sulfoxyl radicals

21 January 2018

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Inactivation of alpha 1-antiproteinase by hydroxyl radicals. The effect of uric acid.

21 January 2018

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L-ascorbic acid quenching of singlet delta molecular oxygen in aqueous media: generalized antioxidant property of vitamin C.

21 January 2018

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Oxidants, antioxidants, and respiratory tract lining fluids

21 January 2018

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Promotion of oxidative damage to arachidonic acid and alpha 1-antiproteinase by anti-inflammatory drugs in the presence of the haem proteins myoglobin and cytochrome C.

21 January 2018

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Use of ascorbic acid to inhibit nitrosation: kinetic and mass transfer considerations for an in vitro system.

21 January 2018

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Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide

21 January 2018

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Studies on Ascorbic Acid. I. Factors Influencing the Ascorbate-Mediated Inhibition of Catalase*

21 January 2018

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Ascorbate-induced free radical toxicity to isolated islet cells.

21 January 2018

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Cell death by oxidative stress and ascorbic acid regeneration in human neuroectodermal cell lines.

21 January 2018

1 reference

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Inhibitory effects of ascorbic acid on growth of leukemic and lymphoma cell lines.

21 January 2018

1 reference

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Prooxidant iron and copper, with ferroxidase and xanthine oxidase activities in human atherosclerotic material

21 January 2018

1 reference

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Metal Ion Release from Mechanically-Disrupted Human Arterial Wall. Implications for the Development of Atherosclerosis

21 January 2018

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Iron and the sex difference in heart disease risk

21 January 2018

1 reference

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Proposed role for a combination of citric acid and ascorbic acid in the production of dietary iron overload: a fundamental cause of disease

21 January 2018

1 reference

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Iron overload cardiomyopathies: new insights into an old disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Effect of vitamin C supplementation on gastric mucosal DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

The molecular genetics of superoxide dismutase in E. coli. An approach to understanding the biological role and regulation of SODS in relation to other elements of the defence system against oxygen toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

The effect of vitamin C on in vivo lipid peroxidation in guinea pigs as measured by pentane and ethane production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

The determination of dehydroascorbic acid and ascorbic acid in the serum and synovial fluid of patients with rheumatoid arthritis (RA).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Dehydroascorbate reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

On the antioxidant effects of ascorbic acid and glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

21 January 2018

1 reference

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Free radical-induced fragmentation of proteins by quercetin.

21 January 2018

1 reference

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Strand scission in DNA by quercetin and Cu(II): identification of free radical intermediates and biological consequences of scission.

21 January 2018

1 reference

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Interactions of flavonoids, trace metals, and oxygen: nuclear DNA damage and lipid peroxidation induced by myricetin.

21 January 2018

1 reference

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Does vitamin C alleviate the symptoms of the common cold?--a review of current evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Vitamin C and the common cold: a retrospective analysis of Chalmers' review

21 January 2018

1 reference

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Ascorbic-acid-induced haemolysis in G-6-PD deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Cataract: relationship between nutrition and oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

The health effects of vitamin C supplementation: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Commentary the Measurement of Oxidative Damage to DNA by HPLC and GC/MS Techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Inactivation of key metabolic enzymes by mixed-function oxidation reactions: possible implication in protein turnover and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Oxidants, antioxidants, and the degenerative diseases of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Spontaneous cancer and its possible relationship to oxygen metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Pathogenesis of genetic haemochromatosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Non-specific serum iron in thalassaemia: an abnormal serum iron fraction of potential toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Serum non-transferrin-bound iron in beta-thalassaemia major patients treated with desferrioxamine and L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Bleomycin-detectable iron in the plasma of premature and full-term neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Iron and coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Serum copper and the risk of acute myocardial infarction: a prospective population study in men in eastern Finland

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Copper and iron are mobilized following myocardial ischemia: possible predictive criteria for tissue injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Ascorbic acid safety: analysis of factors affecting iron absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Ascorbic acid protects against endogenous oxidative DNA damage in human sperm

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Dietary carotenes, vitamin C, and vitamin E as protective antioxidants in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

Ascorbic acid and gastrointestinal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715769609149066

10.3109/10715769609149066

21 January 2018

Identifiers

DOI

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28 September 2017

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