(Q41318459)

29 September 2017

1 reference

title

Just add water! The effect of water on the specificity of protein-ligand binding sites and its potential application to drug design (English)

1 reference

29 September 2017

0 references

1 reference

Ladbury JE

1

1 reference

29 September 2017

1 December 1996

1 reference

29 September 2017

Chemistry and Biology

1 reference

29 September 2017

3

1 reference

29 September 2017

973-980

1 reference

29 September 2017

12

1 reference

Protein hydration in aqueous solution

29 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Hydration of proteins. A comparison of experimental residence times of water molecules solvating the bovine pancreatic trypsin inhibitor with theoretical model calculations

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Water: now you see it, now you don't

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Internal water molecules and H‐bonding in biological macromolecules: A review of structural features with functional implications

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

What makes a binding site a binding site?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Small rearrangements in structures of Fv and Fab fragments of antibody D1.3 on antigen binding

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

A thermodynamic study of the trp repressor-operator interaction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Water-mediated protein-DNA interactions: the relationship of thermodynamics to structural detail

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

The effect of water activity on the association constant and the enthalpy of reaction between lysozyme and the specific antibodies D1.3 and D44.1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Substrate specificity and affinity of a protein modulated by bound water molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

The structural basis of sequence-independent peptide binding by OppA protein

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

The role of water in sequence-independent ligand binding by an oligopeptide transporter protein

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Side-chain conformational entropy in protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

The Entropic Cost of Bound Water in Crystals and Biomolecules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Win some, lose some: enthalpy-entropy compensation in weak intermolecular interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Acquisition and use of calorimetric data for prediction of the thermodynamics of ligand-binding and folding reactions of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

A possible involvement of solvent-induced interactions in drug design

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Distributions of water around amino acid residues in proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Analysis of protein main-chain solvation as a function of secondary structure

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

The interdependence of protein surface topography and bound water molecules revealed by surface accessibility and fractal density measures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Atomic and residue hydrophilicity in the context of folded protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Hydrogen bonding in globular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Buried waters and internal cavities in monomeric proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Hydration in drug design. 1. Multiple hydrogen-bonding features of water molecules in mediating protein-ligand interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Hydration in drug design. 2. Influence of local site surface shape on water binding

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Hydration in drug design. 3. Conserved water molecules at the ligand-binding sites of homologous proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Structure-based drug design: progress, results and challenges

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

Further development of hydrogen bond functions for use in determining energetically favorable binding sites on molecules of known structure. 1. Ligand probe groups with the ability to form two hydrogen bonds

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2896%2990164-7

7 January 2021

10.1016/S1074-5521(96)90164-7

Identifiers

DOI

1 reference

29 September 2017

1 reference

PubMed ID

9000013