(Q41368389)

30 September 2017

title

3-Deazauridine (NSC 126849): an interesting modulator of biochemical response (English)

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30 September 2017

W J Moriconi

1

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30 September 2017

M Slavik

series ordinal

2

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30 September 2017

S Taylor

series ordinal

3

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30 September 2017

publication date

1 January 1986

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Investigational New Drugs

30 September 2017

published in

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30 September 2017

volume

4

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30 September 2017

issue

1

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30 September 2017

page(s)

67-84

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Penetration of 3-deazauridine into human brain, intracerebral tumor, and cerebrospinal fluid

30 September 2017

cites work

1 reference

12 December 2020

Phase II study of 5-azacytidine in solid tumors

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12 December 2020

Incorporation of a potent antileukemic agent, 5-aza-2'-deoxycytidine, into DNA of cells from leukemic mice

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12 December 2020

Cellular differentiation, cytidine analogs and DNA methylation

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12 December 2020

Selective lethal effect of thymidine on human and mouse tumor cells

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12 December 2020

Rational design of arabinosyl nucleosides as antitumor and antiviral agents

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12 December 2020

Some properties of uridine-cytidine kinase from a human malignant lymphoma

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12 December 2020

Transport of uridine and 6-azauridine in human lymphoblastoid cells. Specificity for the uncharged 6-azauridine molecule

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12 December 2020

Inhibition of gross leukemia virus-induced plaque formation in XC cells by 3-deazauridine

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12 December 2020

Studies on the mode of action of 3-deazapyrimidines. 1. Metabolism of 3-deazauridine and 3-deazacytidine in microbial and tumor cells.

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12 December 2020

Preparation and biological activity of various 3-deazapyrimidines and related nucleosides

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12 December 2020

In vitro cytotoxic and biochemical effects of 5-aza-2'-deoxycytidine

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12 December 2020

Altered 5-azacytidine metabolism following 3-deazauridine treatment of L5178Y and human myeloblasts

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12 December 2020

5-Azacytidine, a new, highly effective cancerostatic

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12 December 2020

Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine

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12 December 2020

Kinetics of phosphorylation of 5-aza-2′-deoxycytidine by deoxycytidine kinase

1 reference

12 December 2020

Increased UDP kinase activity in rat and human hepatomas

1 reference

12 December 2020

Enzyme pattern-directed chemotherapy: synergistic interaction of 3-deazauridine with D-galactosamine

1 reference

12 December 2020

Cytidine triphosphate synthetase activity in lymphoproliferative disorders

1 reference

12 December 2020

Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. Clowes Memorial Lecture

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12 December 2020

3-Deazauridine: inhibition of ribonucleic acid virus-induced cytopathogenic effects in vitro

1 reference

12 December 2020

Effect of 3-deazauridine on the metabolism, toxicity, and antitumor activity of azacitidine in mice bearing L1210 leukemia sensitive and resistant to cytarabine

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12 December 2020

Kinetics of deamination of 5-aza-2'-deoxycytidine and cytosine arabinoside by human liver cytidine deaminase and its inhibition by 3-deazauridine, thymidine or uracil arabinoside

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12 December 2020

The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine

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12 December 2020

Selective uridine triphosphate deficiency induced by D-galactosamine in liver and reversed by pyrimidine nucleotide precursors. Effect on ribonucleic acid synthesis.

1 reference

12 December 2020

Transport of uridine and 3-deazauridine in cultured human lymphoblastoid cells.

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12 December 2020

New approaches to the treatment of non-Hodgkin's lymphoma

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12 December 2020

Thymidine as an anticancer agent, alone or in combination. A biochemical appraisal

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12 December 2020

A pilot study of high-dose 1-beta-D-arabinofuranosylcytosine for acute leukemia and refractory lymphoma: clinical response and pharmacology.

1 reference

12 December 2020

Inhibition of RNA virus replication in vitro by 3-deazacytidine and 3-deazauridine.

1 reference

12 December 2020

Clinical pharmacology and human antitumor activity of cytosine arabinoside

1 reference

12 December 2020

Inhibition of protein synthesis in 5-azacytidine-treated HeLa cells

1 reference

12 December 2020

Cytidine and deoxycytidylate deaminase inhibition by uridine analogs

1 reference

12 December 2020

Phase I study of 3-deazauridine in the treatment of adults with solid tumors.

1 reference

12 December 2020

Prevention by testosterone of the intestinal toxicity caused by the antitumor agent 3-deazauridine

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12 December 2020

Phase I trial and pharmacokinetics of a daily x 5 schedule of 3-deazauridine.

1 reference

12 December 2020

Phase II study of 3-deazauridine in advanced colorectal adenocarcinoma

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12 December 2020

Ara-C metabolism: implications for drug resistance and drug interactions

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12 December 2020

Toxicity of combinations of arabinosylcytosine and 3-deazauridine toward neoplastic cells in culture

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12 December 2020

Correlation of cytotoxicity with incorporation of ara-C into DNA

1 reference

12 December 2020

The determination of 5-azapyrimidines and their derivatives in bacterial RNA

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12 December 2020

Increased cytidine 5'-triphosphate synthetase activity in rat and human tumors

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12 December 2020

Pharmacokinetics and disposition of 3-deazauridine in humans.

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12 December 2020

Effects of Thymidine on Deoxyribonucleoside Triphosphate Pools and Deoxyribonucleic Acid Synthesis in Chinese Hamster Ovary Cells

1 reference

12 December 2020

Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.

1 reference

12 December 2020

Metabolism and cytotoxicity of 5-azacytidine in cultured Novikoff rat hepatoma and P388 mouse leukemia cells and their enhancement by preincubation with pyrazofurin

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12 December 2020

Cytotoxicity and mode of action of 5-azacytidine on L1210 leukemia

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12 December 2020

Biochemical mechanisms of drug resistance IV. Development of resistance to 5-azacytidine and simultaneous depression of pyrimidine metabolism in leukemic mice

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12 December 2020

Microbiological production of 5-azacytidine. I. Production and biological activity

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12 December 2020

Mammalian deoxynucleoside kinase. I. Deoxycytidine kinase: purification, properties, and kinetic studies with cytosine arabinoside

1 reference

12 December 2020

Inhibition of glycoprotein and glycolipid synthesis in hamster embryo cells by cytosine arabinoside and hydroxyurea

1 reference

12 December 2020

Thymidine kinase and polyribosome distribution in regenerating rat liver following 5-azacytidine

1 reference

12 December 2020

Inhibition of growth rate and deoxynucleoside triphosphate concentrations in cultured leukemia L1210 cells

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12 December 2020

In vivo cellular kinetic and pharmacological studies of 1-beta-D-arabinofuranosylcytosine and 3-deazauridine chemotherapy for relapsing acute leukemia

1 reference

12 December 2020

Cell cycle arrest as a basis of enhancement of 1-beta-D-arabinofuranosylcytosine anabolism in human lymphoblastoid RPMI 6410 cells cultured with 3-deazauridine

1 reference

12 December 2020

Phase I study on 5-aza-2′-deoxycytidine in children with acute leukemia

1 reference

12 December 2020

Cyclophosphamide, vincristine, methotrexate with leucovorin rescue, and cytarabine (COMLA) combination sequential chemotherapy for advanced diffuse histiocytic lymphoma

1 reference

12 December 2020

Biochemical mechanism of drug resistance. VII. Inhibition of orotic acid metabolism by 5-azacytidine in leukemic mice sensitive and resistant to 5-azacytidine

1 reference

12 December 2020

The trapping of uridine phosphates by D-galactosamine. D-glucosamine, and 2-deoxy-D-galactose. A study on the mechanism of galactosamine hepatitis

1 reference

12 December 2020

Phase I--II study of 3-deazauridine in adults with acute leukemia

1 reference

12 December 2020

Prolongation of the lag period preceding the enhancement of thymidine and thymidylate kinase activity in regenerating rat liver by 5-azacytidine

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12 December 2020

Drug sequence-dependent toxicity and small bowel mucosal injury in mice treated with low doses of 3-deazauridine and 1-beta-D-arabinofuranosylcytosine

1 reference

12 December 2020

The incorporation of 3H-cytosine arabinoside and its effect on murine leukemic cells (L5178Y)

1 reference

12 December 2020

Synergistic action of 5-aza-2'-deoxycytidine and 3-deazauridine on L1210 leukemic cells and EMT6 tumor cells

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12 December 2020

5-Azacytidine—A New Anticancer Drug with Significant Activity in Acute Myeloblastic Leukemia

1 reference

12 December 2020

The regulation of pyrimidine nucleotide level and its role in experimental hepatitis

1 reference

12 December 2020

The regulation of thymidylate biosynthesis in Novikoff hepatoma cells and the effects of amethopterin, 5-fluorodeoxyuridine, and 3-deazauridine

1 reference

12 December 2020

Combination therapy for diffuse histiocytic lymphoma that includes antimetabolites

1 reference

12 December 2020

5-Azacytidine. A new anticancer drug with effectiveness in acute myelogenous leukemia

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12 December 2020

The disposition of 3-deazauridine in mice

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12 December 2020

A synopsis of recent investigations of 6-azauridine (NSC-32074)

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12 December 2020

Effect of intravenous infusion of 5-aza-2'-deoxycytidine on survival time of mice with L1210 leukemia

1 reference

12 December 2020

Association of decreased uridine and deoxycytidine kinase with enhanced RNA and DNA polymerase in mouse leukemic cells resistant to 5-azacytidine and 5-aza-2'-deoxycytidine

1 reference

12 December 2020

Studies on the Mechanism of Galactosamine Hepatitis: Accumulation of Galactosamine-1-Phosphate and its Inhibition of UDP-Glucose Pyrophosphorylase

1 reference

12 December 2020

The effect of-beta-D-arabinofuranosylcytosine on growth, viability, and DNA synthesis of mouse L-cells

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12 December 2020

Purine and pyrimidine enzymic programs and nucleotide pattern in sarcoma

1 reference

12 December 2020

A proposed mechanism of action of 1-beta-D-arabinofuranosyl-cytosine as an inhibitor of the growth of leukemic cells

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12 December 2020

Nucleotide contents of ascites hepatoma cells and their changes induced by D-galactosamine

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12 December 2020

Identifiers

DOI

10.1007/BF00172020

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Dimensions Publication ID

30 September 2017

1012984197

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Fatcat ID

release_dku4eo47kjf35ks32ut3qeheme

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Fatcat

https://api.fatcat.wiki/v0/release/dku4eo47kjf35ks32ut3qeheme

24 November 2022

mapped directly with Wikidata item

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