(Q41398474)

30 September 2017

1 reference

title

Acute rejection of renal allografts: mechanistic insights and therapeutic options (English)

1 reference

30 September 2017

Suthanthiran M

1

1 reference

30 September 2017

language of work or name

English

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publication date

1 April 1997

1 reference

30 September 2017

1 reference

30 September 2017

volume

51

1 reference

30 September 2017

issue

4

1 reference

30 September 2017

page(s)

1289-1304

1 reference

https://scigraph.springernature.com/pub.10.1038/ki.1997.176

30 September 2017

exact match

0 references

cites work

Renal transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

High Survival Rates of Kidney Transplants from Spousal and Living Unrelated Donors

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Risk factors for chronic rejection in renal allograft recipients.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Nonimmunologic causes of late renal graft loss

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Factors Contributing to the Declining Mortality Rate in Renal Transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Comparative effects of pregnancy, transfusion, and prior graft rejection on sensitization and renal transplant results

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

International standardization of criteria for the histologic diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathology

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

https://api.crossref.org/works/10.1038%2FKI.1997.176

1 reference

7 January 2021

Antigen presentation.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Indirect presentation of MHC antigens in transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

The T cell receptor/CD3 complex: a dynamic protein ensemble

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A novel model for antigen-dependent activation of normal human T cells. Transmembrane signaling by crosslinkage of the CD3/T cell receptor-alpha/beta complex with the cluster determinant 2 antigen

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

The CD2 antigen associates with the T-cell antigen receptor CD3 antigen complex on the surface of human T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

T cell antigen receptor activation pathways: The tyrosine kinase connection

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Models of T cell anergy: is there a common molecular mechanism?

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Role of the CD28 receptor in T-cell activation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

CTLA-4 is a second receptor for the B cell activation antigen B7

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

The Yin and Yang of T cell costimulation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

CD2 antigen targeting reduces intragraft expression of mRNA-encoding granzyme B and IL-10 and induces tolerance

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

How B and T cells talk to each other

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Identity and Cytotoxic Capacity of Cells Infiltrating Renal Allografts

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Wound macrophages express TGF-alpha and other growth factors in vivo: analysis by mRNA phenotyping

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

The strong correlation of cytotoxic T lymphocyte-specific serine protease gene transcripts with renal allograft rejection

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Intragraft expression of IL-10 messenger RNA: a novel correlate of renal allograft rejection

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Intragraft TGF-beta 1 mRNA: a correlate of interstitial fibrosis and chronic allograft nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Sequential analysis of IL-2 gene transcription in renal transplants

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Cloning of two genes that are specifically expressed in activated cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

The isolation and characterization of a family of serine protease genes expressed in activated cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

The pore-forming protein (perforin) of cytolytic T lymphocytes is immunologically related to the components of membrane attack complex of complement through cysteine-rich domains

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Structure and function of human perforin

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Administration of an anti-interleukin 2 receptor monoclonal antibody prolongs cardiac allograft survival in mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Therapy with monoclonal antibody to interleukin 2 receptor spares suppressor T cells and prevents or reverses acute allograft rejection in rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A randomized prospective trial of anti-Tac monoclonal antibody in human renal transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Randomized controlled trial of a monoclonal antibody against the interleukin-2 receptor (33B3.1) as compared with rabbit antithymocyte globulin for prophylaxis against rejection of renal allografts

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Cytokines: coordinators of immune and inflammatory responses

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

The role of IL-10 in crossregulation of TH1 and TH2 responses

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Selection of a human T helper type 1-like T cell subset by mycobacteria

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Regulation of immunity to parasites by T cells and T cell-derived cytokines

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Stigma variations: observations on suppressor T cells and leprosy

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Cytokines and the Th1/Th2 paradigm in transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Immunophilin-sensitive protein phosphatase action in cell signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Evidence that glucocorticosteroids block expression of the human interleukin-6 gene by accessory cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Immunosuppressive and other effects of mycophenolic acid and an ester prodrug, mycophenolate mofetil

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Rapamycin (sirolimus, rapamune).

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Treatment with rapamycin and mycophenolic acid reduces arterial intimal thickening produced by mechanical injury and allows endothelial replacement.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

The side effect profile of sirolimus: a phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A new antitumor antibiotic, spergualin: Isolation and antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Interaction of the immunosuppressant deoxyspergualin with a member of the Hsp70 family of heat shock proteins

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Therapy of acute cadaveric renal allograft rejection with adjunctive antithymocyte globulin

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A randomized clinical trial of OKT3 monoclonal antibody for acute rejection of cadaveric renal transplants

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Treatment of acute cellular rejection with T10B9.1A-31 or OKT3 in renal allograft recipients

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A humanized antibody that binds to the interleukin 2 receptor

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Immunologic tolerance: collaboration between antigen and lymphokines

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Molecular and cellular aspects of immunologic tolerance

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Self-tolerance and autoimmunity

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

CCETS Basic Science Lecture. Transplantation tolerance

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Induction of donor-specific unresponsiveness by intrathymic islet transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Unraveling immune privilege

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A role for CD95 ligand in preventing graft rejection

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Relevant targets for therapy with monoclonal antibodies in allograft transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Reduced human IgG anti-ATGAM antibody formation in renal transplant recipients receiving mycophenolate mofetil

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Transgenic expression of IL-10 in pancreatic islet A cells accelerates autoimmune insulitis and diabetes in non-obese diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Pancreatic islet production of murine interleukin-10 does not inhibit immune-mediated tissue destruction

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Mutations that perturb cyclophilin A ligand binding pocket confer cyclosporin A resistance in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

FK506 "rescue" for resistant rejection of renal allografts under primary cyclosporine immunosuppression

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

A multicenter analysis of the first experience with FK506 for induction and rescue therapy after pancreas transplantation

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta).

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Transforming growth factor beta in tissue fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Cyclosporine stimulates expression of transforming growth factor-beta in renal cells. Possible mechanism of cyclosporines antiproliferative effects.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Cyclosporine enhances the expression of TGF-beta in the juxtaglomerular cells of the rat kidney

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Role of transforming growth factor-beta 1 in experimental chronic cyclosporine nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Distribution of extracellular matrix receptors in various forms of glomerulonephritis

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Quantification of glomerular TGF-beta 1 mRNA in patients with diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Intraglomerular expression of transforming growth factor-beta 1 (TGF-beta 1) mRNA in patients with glomerulonephritis: quantitative analysis by competitive polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Expression of transforming growth factor-beta isoforms in human glomerular diseases

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Interleukin-1 receptor antagonist halts the progression of established crescentic glomerulonephritis in the rat

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Interleukin-1 in crescentic glomerulonephritis

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Skin allograft rejection in CD28-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.1997.176

7 January 2021

Identifiers

DOI

10.1038/KI.1997.176

1 reference

30 September 2017

1 reference