(Q41420722)

English

Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125.

scientific article published on 13 March 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125. (English)

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

inferred from title

11

object named as

Hilal A Lashuel

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

3

object named as

Bruno Fauvet

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Europe PubMed Central

30 September 2017

PMC publication ID

1

object named as

Mirva Hejjaoui

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

6

object named as

Igor Dikiy

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

7

object named as

Michel Prudent

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Sara M Butterfield

2

object named as

Sara Butterfield

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

author name string

Filip Vercruysse

4

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Jia Cui

5

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Diana Olschewski

8

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Europe PubMed Central

PMC publication ID

30 September 2017

Yan Zhang

9

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Europe PubMed Central

PMC publication ID

30 September 2017

David Eliezer

10

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Europe PubMed Central

PMC publication ID

30 September 2017

language of work or name

0 references

publication date

13 March 2012

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

number of pages

15

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based on heuristic

inferred from page(s)

Journal of the American Chemical Society

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Europe PubMed Central

PMC publication ID

30 September 2017

134

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Europe PubMed Central

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30 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

5196-5210

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

Chemistry and biology of the ubiquitin signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival

1 reference

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1 October 2017

Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Phosphorylation of synucleins by members of the Polo-like kinase family

1 reference

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1 October 2017

Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation

1 reference

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1 October 2017

Expressed protein ligation: a resourceful tool to study protein structure and function.

1 reference

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1 October 2017

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

1 reference

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1 October 2017

Protein phosphorylation by semisynthesis: from paper to practice

1 reference

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1 October 2017

A semisynthetic strategy to generate phosphorylated and acetylated histone H2B.

1 reference

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1 October 2017

Relationship between alpha synuclein phosphorylation, proteasomal inhibition and cell death: relevance to Parkinson's disease pathogenesis

1 reference

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1 October 2017

Chemoselective ligation and modification strategies for peptides and proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Phosphorylation at Ser-129 but not the phosphomimics S129E/D inhibits the fibrillation of alpha-synuclein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

The phosphorylation state of Ser-129 in human alpha-synuclein determines neurodegeneration in a rat model of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Interactions between metals and alpha-synuclein--function or artefact?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Structure and properties of alpha-synuclein and other amyloids determined at the amino acid level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Protein kinase structure and function analysis with chemical tools.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles.

1 reference

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1 October 2017

Using NMRView to visualize and analyze the NMR spectra of macromolecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Parkinson's disease and related alpha-synucleinopathies are brain amyloidoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Chemical Dissection of the Effects of Tyrosine Phosphorylation of SHP-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Semisynthesis of proteins by expressed protein ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

alpha-Synuclein is phosphorylated in synucleinopathy lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Multiple phosphorylation of alpha-synuclein by protein tyrosine kinase Syk prevents eosin-induced aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Activated Fyn phosphorylates alpha-synuclein at tyrosine residue 125.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

alpha-synuclein is phosphorylated by members of the Src family of protein-tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Synucleins are a novel class of substrates for G protein-coupled receptor kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

New animal models for Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Intein-mediated protein ligation: harnessing nature's escape artists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Expressed protein ligation: a general method for protein engineering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Alpha-synuclein in Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

1 October 2017

Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

11 June 2018

Polycation-induced oligomerization and accelerated fibrillation of human alpha-synuclein in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

11 June 2018

Copper(II)-induced self-oligomerization of alpha-synuclein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

11 June 2018

Rapid in situ neutralization protocols for Boc and Fmoc solid-phase chemistries

1 reference

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11 June 2018

The Alzheimer's disease related tau protein as a new target for chemical protein engineering.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Allostery in a disordered protein: oxidative modifications to α-synuclein act distally to regulate membrane binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Non-classical exocytosis of alpha-synuclein is sensitive to folding states and promoted under stress conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Modular strategy for the semisynthesis of a K+ channel: investigating interactions of the pore helix.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Free-radical-based, specific desulfurization of cysteine: a powerful advance in the synthesis of polypeptides and glycopolypeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Cellular stabilization of the melatonin rhythm enzyme induced by nonhydrolyzable phosphonate incorporation.

1 reference

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19 August 2018

Nuclear localization of alpha-synuclein and its interaction with histones

1 reference

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19 August 2018

A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Activation of Pyk2/RAFTK induces tyrosine phosphorylation of alpha-synuclein via Src-family kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592575

19 August 2018

Conformational properties of alpha-synuclein in its free and lipid-associated states

1 reference

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19 August 2018

[Difluro(phosphono)methyl]phenylalanine-containing peptide inhibitors of protein tyrosine phosphatases

1 reference

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19 August 2018

Ready Access to Fluorinated Phosphonate Mimics of Secondary Phosphates. Synthesis of the (alpha,alpha-Difluoroalkyl)phosphonate Analogues of L-Phosphoserine, L-Phosphoallothreonine, and L-Phosphothreonine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site specificity of p72 syk protein tyrosine kinase: efficient phosphorylation of motifs recognized by Src homology 2 domains of the Src family

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of a protein tyrosine phosphatase by tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards elucidation of the role of ubiquitination in the pathogenesis of Parkinson's disease with semisynthetic ubiquitinated α-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-stranded DNA stimulates the fibrillation of alpha-synuclein in vitro and is associated with the mature fibrils: an electron microscopy study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22339654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA210866J

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

ResearchGate publication ID

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