(Q41435517)

30 September 2017

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title

Use of aminoglycosides in elderly patients. Pharmacokinetic and clinical considerations (English)

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30 September 2017

Mörike K

1

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30 September 2017

Schwab M

series ordinal

2

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30 September 2017

Klotz U

series ordinal

3

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30 September 2017

publication date

1 April 1997

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30 September 2017

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30 September 2017

volume

10

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30 September 2017

issue

4

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30 September 2017

page(s)

259-277

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https://scigraph.springernature.com/pub.10.2165/00002512-199710040-00003

30 September 2017

exact match

0 references

cites work

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Nephrotoxicity, high frequency ototoxicity, efficacy and serum kinetics of once versus thrice daily dosing of netilmicin in patients with serious infections.

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Comparative kinetics and efficacy of amikacin administered once or twice daily in the treatment of systemic gram-negative infections.

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Once versus thrice daily gentamicin in patients with serious infections

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Effect of age and renal function on gentamicin pharmacokinetic parameters

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Inhibition of kidney lysosomal phospholipases A and C by aminoglycoside antibiotics: possible mechanism of aminoglycoside toxicity

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Influence of dosage schedule on renal cortical accumulation of amikacin and tobramycin in man

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Aging and cancer: are telomeres and telomerase the connection?

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Pharmacokinetics of once-daily amikacin in elderly patients

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Effect of furosemide on aminoglycoside-induced nephrotoxicity and auditory toxicity in humans

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Inactivation of antibiotics and the dissemination of resistance genes

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Comparison of once-daily and thrice-daily netilmicin regimens in serious systemic infections: a multicenter study in six Asian countries

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Wide interpatient variations in gentamicin dose requirements for geriatric patients

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Influence of age on tobramycin pharmacokinetics in patients with normal renal function

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Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males

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12 December 2020

Does administration of an aminoglycoside in a single daily dose affect its efficacy and toxicity?

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12 December 2020

Gentamicin disposition in young and elderly patients with various degrees of renal function

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12 December 2020

Comparative activity of netilmicin, gentamicin, amikacin, and tobramycin against Pseudomonas aeruginosa and Enterobacteriaceae

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12 December 2020

Mechanisms and spectrum of streptomycin resistance in a natural population of Pseudomonas aeruginosa

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12 December 2020

Mild nephrotoxicity associated with vancomycin use.

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12 December 2020

Subcellular distribution of gentamicin in proximal tubular cells, determined by immunogold labeling

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12 December 2020

Prospective randomized study of once-daily versus thrice-daily netilmicin regimens in patients with intraabdominal infections

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12 December 2020

Specificity of renal tubular damage criteria for aminoglycoside nephrotoxicity in critically ill patients

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12 December 2020

Single or multiple daily doses of aminoglycosides: a meta-analysis

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12 December 2020

Risk Factors for Nephrotoxicity in Patients Treated with Aminoglycosides

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12 December 2020

Genetic aspects of antibiotic induced deafness: mitochondrial inheritance

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12 December 2020

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12 December 2020

Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.

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12 December 2020

Efficacy and toxicity of single daily doses of amikacin and ceftriaxone versus multiple daily doses of amikacin and ceftazidime for infection in patients with cancer and granulocytopenia. The International Antimicrobial Therapy Cooperative Group of t

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Kinetics of gentamicin uptake and release in the rat. Comparison of inner ear tissues and fluids with other organs

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12 December 2020

Human cochlear pathology in aminoglycoside ototoxicity--a review

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12 December 2020

High-frequency audiometric monitoring for early detection of aminoglycoside ototoxicity

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The post-antibiotic effect

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12 December 2020

A multicentric study of netilmicin once daily versus thrice daily in patients with appendicitis and other intra-abdominal infections

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12 December 2020

Inner ear concentrations and ototoxicity of different antibiotics in local and systemic application.

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12 December 2020

Once-daily dosing decreases renal accumulation of gentamicin and netilmicin

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12 December 2020

THE AGGRAVATING EFFECT OF SOME ANTIBIOTICS ON THE NEUROMUSCULAR BLOCKADE IN MYASTHENIA GRAVIS

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12 December 2020

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12 December 2020

The bactericidal action of streptomycin: membrane permeabilization caused by the insertion of mistranslated proteins into the cytoplasmic membrane of Escherichia coli and subsequent caging of the antibiotic inside the cells due to degradation of the

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12 December 2020

Aminoglycoside nephrotoxicity

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12 December 2020

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12 December 2020

Aminoglycoside Administration as a Single Daily Dose : An Improvement to Current Practice or a Repeat of Previous Errors?

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12 December 2020

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12 December 2020

Aminoglycoside accumulation kinetics in rat renal parenchyma

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12 December 2020

Once-daily dosing of aminoglycosides

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12 December 2020

Once-daily aminoglycoside dosing in immunocompetent adults: a meta-analysis

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12 December 2020

Nonoliguric acute renal failure

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12 December 2020

Once-daily dosing regimen for aminoglycoside plus beta-lactam combination therapy of serious bacterial infections: comparative trial with netilmicin plus ceftriaxone

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12 December 2020

The Neurotoxicity of Antibacterial Agents

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12 December 2020

Aminoglycoside cochlear ototoxicity

1 reference

12 December 2020

Single-dose treatment with netilmicin for different clinical forms of urinary tract infections

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12 December 2020

Forecasting individual pharmacokinetics

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12 December 2020

Infections in elderly persons. An altered clinical presentation

1 reference

12 December 2020

Clinical significance of renal changes engendered by aminoglycosides in man

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12 December 2020

Correlation between renal membrane binding and nephrotoxicity of aminoglycosides

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12 December 2020

Once-daily aminoglycoside therapy

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12 December 2020

Treatment of infections in elderly patients.

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12 December 2020

Growth characteristics of cultured human proximal tubule cells exposed to aminoglycoside antibiotics.

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12 December 2020

Antibiotic blockade of neuromuscular function

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12 December 2020

Pharmacodynamic parameters and toxicity of netilmicin (6 milligrams/kilogram/day) given once daily or in three divided doses to cancer patients with urinary tract infection

1 reference

12 December 2020

Netilmicin in the treatment of gram-negative bacteremia: single daily versus multiple daily dosage

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12 December 2020

Single daily ceftriaxone and tobramycin in the empirical management of febrile neutropenic patients: a randomised trial

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12 December 2020

Once-daily gentamicin: translating theory into practice

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12 December 2020

Accuracy of pharmacokinetic dose determination of gentamicin in geriatric patients

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12 December 2020

Infections in the elderly

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12 December 2020

Prediction of creatinine clearance from serum creatinine

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12 December 2020

Early detection of aminoglycoside nephrotoxicity with urinary beta-2-microglobulin

1 reference

12 December 2020

Gentamicin pharmacokinetics in 1,640 patients: method for control of serum concentrations

1 reference

12 December 2020

Incidence of and significant risk factors for aminoglycoside-associated nephrotoxicity in patients dosed by using individualized pharmacokinetic monitoring

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12 December 2020

Five-year surveillance of aminoglycoside usage in a university hospital.

1 reference

12 December 2020

Effect of aging on gentamicin nephrotoxicity and pharmacokinetics in rats

1 reference

12 December 2020

Once-daily versus thrice-daily dosing of netilmicin in combination with beta-lactam antibiotics as empirical therapy for febrile neutropenic patients

1 reference

12 December 2020

Antibiotic uptake: unusual results for unusual molecules

1 reference

12 December 2020

Once-daily aminoglycoside dosing

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12 December 2020

The inductive role of ionic binding in the bactericidal and postexposure effects of aminoglycoside antibiotics with implications for dosing

1 reference

12 December 2020

Once- versus twice-daily amikacin regimen: efficacy and safety in systemic gram-negative infections. Scandinavian Amikacin Once Daily Study Group.

1 reference

12 December 2020

Once daily administration of netilmicin compared with thrice daily, both in combination with metronidazole, in gangrenous and perforated appendicitis

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12 December 2020

High-level resistance to gentamicin in clinical isolates of Streptococcus (Enterococcus) faecium

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12 December 2020

Renal clearance and tissue accumulation of gentamicin

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12 December 2020

Misreading of RNA codewords induced by aminoglycoside antibiotics

1 reference

12 December 2020

Comparative nephrotoxicity of aminoglycoside antibiotics in rats

1 reference

12 December 2020

Identification and functional characterization of the protein controlled by the streptomycin-resistant locus in E. coli

1 reference

12 December 2020

Clinical response to aminoglycoside therapy: importance of the ratio of peak concentration to minimal inhibitory concentration

1 reference

12 December 2020

Intravenous administration of gentamicin once daily versus thrice daily in adults

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12 December 2020

Aminoglycoside-induced ototoxicity

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12 December 2020

Disposition kinetics of amikacin in patients with renal impairment after intramuscular administration.

1 reference

12 December 2020

Mitochondrial ribosomal RNA gene mutation in a patient with sporadic aminoglycoside ototoxicity.

1 reference

12 December 2020

Absorption of orally administered neomycin and kanamycin with special reference to patients with severe hepatic and renal disease

1 reference

12 December 2020

Influence of age on amikacin pharmacokinetics in patients without renal disease. Comparison with gentamicin and tobramycin

1 reference

12 December 2020

Effect and pharmacokinetics of netilmicin given as bolus intramuscular administration: an open comparative trial versus amikacin and fosfomycin in elderly patients affected by urinary tract infections.

1 reference

12 December 2020

Comparison of the nephrotoxicity and auditory toxicity of tobramycin and amikacin

1 reference

12 December 2020

Vestibular ototoxicity. Clinical considerations.

1 reference

12 December 2020

Antimicrobial therapy. Cost-benefit considerations

1 reference

12 December 2020

Comparative uptake of gentamicin, netilmicin, and amikacin in the guinea pig cochlea and vestibule

1 reference

12 December 2020

Adverse antibiotic effects associated with renal insufficiency

1 reference

12 December 2020

Estimating creatinine clearance in elderly patients with low serum creatinine concentrations.

1 reference

12 December 2020

Easier monitoring of aminoglycoside therapy with once-daily dosing schedules

1 reference

12 December 2020

A study of amikacin given once versus twice daily in serious infections

1 reference

12 December 2020

Why Monitor Serum Levels of Gentamicin?

1 reference

12 December 2020

Studies on gentamicin-induced labilization of rat kidney lysosomes in vitro. Possible protection by selenium

1 reference

12 December 2020

Nephrotoxicity of vancomycin and aminoglycoside therapy separately and in combination

1 reference

12 December 2020

Randomized trials of aminoglycoside antibiotics: quantitative overview

1 reference

12 December 2020

Aminoglycoside toxicity and relation to dose regimen.

1 reference

12 December 2020

Use of therapeutic drug monitoring in pharmacoeconomics.

1 reference

12 December 2020

The Effect of Age on Creatinine Clearance in Men: A Cross-sectional and Longitudinal Study

1 reference

12 December 2020

A molecular basis for human hypersensitivity to aminoglycoside antibiotics

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12 December 2020

Pharmacokinetics of dosing regimens which utilize multiple intravenous infusions: gentamicin in burn patients

1 reference

12 December 2020

Pharmacokinetic contributions to postantibiotic effects. Focus on aminoglycosides

1 reference

12 December 2020

Inhibition of lysosomal phospholipases by aminoglycoside antibiotics: in vitro comparative studies

1 reference

12 December 2020

Urinary casts as an indicator of renal tubular damage in patients receiving aminoglycosides

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12 December 2020

Roles of ribosomal binding, membrane potential, and electron transport in bacterial uptake of streptomycin and gentamicin

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12 December 2020

Once-daily dosing of gentamicin: experience with therapeutic drug monitoring and Bayesian pharmacokinetics.

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12 December 2020

Kidney tissue repair after nephrotoxic injury: biochemical and morphological characterization

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12 December 2020

Urinary tract infection in the elderly

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12 December 2020

Aminoglycoside antibiotics in clinical use.

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12 December 2020

Comparison of the efficacy and safety of amikacin once or twice-a-day in the treatment of severe gram-negative infections in the elderly

1 reference

12 December 2020

Single-dose daily gentamicin therapy in urinary tract infection

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12 December 2020

1 reference

12 December 2020

Antimicrobial Prophylaxis for Appendectomy and Colorectal Surgery

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12 December 2020

Mechanism of Inhibition of Ribosomes by Streptomycin

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12 December 2020

Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin

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12 December 2020

Aminoglycoside monitoring in the once- or twice-daily era. The Dutch situation considered

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12 December 2020

Aminoglycosides--50 years on

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12 December 2020

Univariate and multivariate analyses of risk factors predisposing to auditory toxicity in patients receiving aminoglycosides

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12 December 2020

Risk factors and comparisons of clinical nephrotoxicity of aminoglycosides

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12 December 2020

Interaction of gentamicin with the A band and B band lipopolysaccharides of Pseudomonas aeruginosa and its possible lethal effect

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12 December 2020

Geriatric Pharmacology: Basic and Clinical Considerations*

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12 December 2020

Damage and regeneration of hair cell ciliary bundles in a fish ear following treatment with gentamicin

1 reference

12 December 2020

Predictive value of urinary N-acetyl-beta-D-glucosaminidase (NAG), alanine-aminopeptidase (AAP) and beta-2-microglobulin (beta 2M) in evaluating nephrotoxicity of gentamicin

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12 December 2020

Gentamicin binding to the isolated crista ampullaris of the guinea pig.

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12 December 2020

Risk factors for the development of auditory toxicity in patients receiving aminoglycosides.

1 reference

12 December 2020

Tobramycin inactivation by carbenicillin, ticarcillin, and piperacillin

1 reference

12 December 2020

The postantibiotic effect: a review of in vitro and in vivo data

1 reference

12 December 2020

A controlled investigation of the pharmacokinetics of gentamicin and tobramycin in obese subjects

1 reference

12 December 2020

1 reference

12 December 2020

What is the evidence for once-daily aminoglycoside therapy?

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12 December 2020

Netilmicin pharmacokinetics after single intravenous doses to elderly male patients

1 reference

12 December 2020

The process and theories of aging

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12 December 2020

Intercostal muscle biopsy studies in myasthenia gravis: clinical correlations and the direct effects of drugs and myasthenic serum

1 reference

12 December 2020

Pharmacokinetic Optimisation of Drug Therapy in Elderly Patients

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12 December 2020

Kinetic model for gentamicin dosing with the use of individual patient parameters

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12 December 2020

Therapeutic drug monitoring

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12 December 2020

10.2165/00002512-199710040-00003

Identifiers

DOI

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Dimensions Publication ID

30 September 2017

1020408468

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