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English
Insulin internalization and other signaling pathways in the pleiotropic effects of insulin.
scientific article published on January 1997
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Insulin internalization and other signaling pathways in the pleiotropic effects of insulin
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
main subject
pleiotropy
1 reference
based on heuristic
inferred from title
author name string
R M Smith
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
S Harada
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
L Jarett
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 January 1997
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
International Review of Cytology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
173
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
243-280
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
cites work
Cellular localization of insulin-degrading enzyme in rat liver using monoclonal antibodies specific for this enzyme
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Fibroblast growth factor-2 (FGF-2) in the nucleus: translocation process and targets
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Multiple endocytic pathways
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Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.
1 reference
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Regulation of thyroid hormone receptor-mediated transcription by a cytosol protein
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7 January 2021
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Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals
1 reference
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Crossref
reference URL
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7 January 2021
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Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study
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Crossref
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Selective activation of the rat hepatic endosomal insulin receptor kinase. Role for the endosome in insulin signaling
1 reference
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Crossref
reference URL
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7 January 2021
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Intracellular signal transduction: The role of endosomes
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Insulin-induced and constitutive internalization of the insulin receptor
1 reference
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Crossref
reference URL
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7 January 2021
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Insulin receptor kinase activation releases a constraint maintaining the receptor on microvilli
1 reference
stated in
Crossref
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7 January 2021
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inferred from DOI database lookup
Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Two steps of insulin receptor internalization depend on different domains of the beta-subunit
1 reference
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Crossref
reference URL
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7 January 2021
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Requirement of nuclear prolactin for interleukin-2--stimulated proliferation of T lymphocytes
1 reference
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Activation of c-fos gene expression by a kinase-deficient epidermal growth factor receptor
1 reference
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1 reference
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The interaction of 125I-insulin with cultured 3T3-L1 adipocytes: quantitative analysis by the hypothetical grain method
1 reference
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Iodixanol: a nonionic iso-osmotic centrifugation medium for the formation of self-generated gradients
1 reference
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Insulin binding to isolated liver nuclei from obese and lean mice
1 reference
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Crossref
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7 January 2021
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Insulin and alpha 2-macroglobulin-methylamine undergo endocytosis by different mechanisms in rat adipocytes: I. Comparison of cell surface events
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Binding of insulin to isolated nuclei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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inferred from DOI database lookup
The arguments for pre-existing early and late endosomes
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Nonreceptor mediated nuclear accumulation of insulin in H35 rat hepatoma cells
1 reference
stated in
Crossref
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7 January 2021
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1,10-Phenanthroline increases nuclear accumulation of insulin in response to inhibiting insulin degradation but has a biphasic effect on insulin's ability to increase mRNA levels
1 reference
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Insulin-induced egr-1 expression in Chinese hamster ovary cells is insulin receptor and insulin receptor substrate-1 phosphorylation-independent. Evidence of an alternative signal transduction pathway
1 reference
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reference URL
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7 January 2021
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Demonstration of specific insulin binding to cytosolic proteins in H35 hepatoma cells, rat liver and skeletal muscle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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inferred from DOI database lookup
Dexamethasone inhibits insulin binding to insulin-degrading enzyme and cytosolic insulin-binding protein p82
1 reference
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Crossref
reference URL
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7 January 2021
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Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation
1 reference
stated in
Crossref
reference URL
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7 January 2021
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In vivo association of [125I]-insulin with a cytosolic insulin-degrading enzyme: detection by covalent cross-linking and immunoprecipitation with a monoclonal antibody
1 reference
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Crossref
reference URL
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BiP (GRP78), an essential hsp70 resident protein in the endoplasmic reticulum
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Insulin Regulation of Membrane-associated Insulin Receptor Substrate 1
1 reference
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Crossref
reference URL
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7 January 2021
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Identity of the immunoglobulin heavy-chain-binding protein with the 78,000-dalton glucose-regulated protein and the role of posttranslational modifications in its binding function
1 reference
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Crossref
reference URL
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7 January 2021
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Topology of glutathione-insulin transhydrogenase in rat liver microsomes.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Preimplantation mouse embryos internalize maternal insulin via receptor-mediated endocytosis: pattern of uptake and functional correlations
1 reference
stated in
Crossref
reference URL
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7 January 2021
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A Grb2-associated docking protein in EGF- and insulin-receptor signalling
1 reference
stated in
Crossref
reference URL
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7 January 2021
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Movement of internalized ligand-receptor complexes along a continuous endosomal reticulum
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin binding sites on rat liver nuclear membranes: Biochemical and immunofluorescent studies
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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Molecular cloning and tissue distribution of PHAS-I, an intracellular target for insulin and growth factors
1 reference
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reference URL
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7 January 2021
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1 reference
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7 January 2021
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1 reference
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reference URL
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7 January 2021
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Phosphoinositide 3-kinase as an upstream regulator of the small GTP-binding protein Rac in the insulin signaling of membrane ruffling
1 reference
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Crossref
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7 January 2021
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Dynamics of signaling during insulin-stimulated endocytosis of its receptor in adipocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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The expression of and insulin binding to cellular thyroid hormone binding protein, but not insulin degrading enzyme, is increased during 3T3-L1 adipocytes differentiation
1 reference
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7 January 2021
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1 reference
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Crossref
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7 January 2021
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1 reference
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Crossref
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7 January 2021
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1 reference
stated in
Crossref
reference URL
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7 January 2021
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1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of protein synthesis by internalized insulin
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
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1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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1 reference
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reference URL
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7 January 2021
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Multiple pathways for ligand internalization in rat hepatocytes II: Effect of hyperosmolarity and contribution of fluid-phase endocytosis
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Regulation of gene expression by insulin
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
Enhanced accumulation of mRNA for 78-kilodalton glucose-regulated protein (GRP78) in tissues of nonobese diabetic mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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1 reference
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7 January 2021
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1 reference
stated in
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7 January 2021
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1 reference
stated in
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7 January 2021
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1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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Chimeric receptors expressing juxtamembrane sequences of the insulin receptor undergo rapid endocytosis in the absence of receptor tyrosine kinase activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the growth of murine fibroblasts that express human insulin receptors. I. The effect of insulin in the absence of other growth factors
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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inferred from DOI database lookup
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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Substrates and signalling complexes: the tortured path to insulin action
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal growth factor and insulin stimulate nuclear pore-mediated macromolecular transport in isolated rat liver nuclei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
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inferred from DOI database lookup
Differential effect of insulin and epidermal growth factor on the mRNA translocation system and transport of specific poly(A+) mRNA and poly(A-) mRNA in isolated nuclei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of physiological concentrations of insulin and antidiabetic drugs on RNA release from isolated liver nuclei
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of insulin degradation by hepatoma cells after microinjection of monoclonal antibodies to a specific cytosolic protease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cytosolic protein tyrosine kinase in rat adipocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A simplified method of producing biologically active monomeric ferritin-insulin for use as a high resolution ultrastructural marker for occupied insulin receptors
1 reference
stated in
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7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative ultrastructural analysis of receptor-mediated insulin uptake into adipocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ultrastructural evidence for the accumulation of insulin in nuclei of intact 3T3-L1 adipocytes by an insulin-receptor mediated process
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preparation and characterization of a colloidal gold-insulin complex with binding and biological activities identical to native insulin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immunoelectron microscopic demonstration of insulin-stimulated translocation of glucose transporters to the plasma membrane of isolated rat adipocytes and masking of the carboxyl-terminal epitope of intracellular GLUT4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
retrieved
7 January 2021
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inferred from DOI database lookup
The role of receptor kinase activity and the NPEY960 motif in insulin-accelerated receptor-mediated insulin internalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962479-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of receptor-mediated endocytosis
1 reference
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7 January 2021
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Immunological demonstration of the accumulation of insulin, but not insulin receptors, in nuclei of insulin-treated cells
1 reference
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reference URL
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7 January 2021
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The state of differentiation of embryonic chicken lens cells determines insulin-like growth factor I internalization
1 reference
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reference URL
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7 January 2021
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Late endosomes derive from early endosomes by maturation
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reference URL
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7 January 2021
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Insulin receptor signaling through non‐tyrosine kinase pathways: Evidence from anti‐receptor antibodies and insulin receptor mutants
1 reference
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Crossref
reference URL
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7 January 2021
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Tubular early endosomal networks in AtT20 and other cells
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reference URL
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7 January 2021
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Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump.
1 reference
stated in
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reference URL
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7 January 2021
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Interaction of insulin analogs, glucagon, growth hormone, vasopressin, oxytocin, and scrambled forms of ribonuclease and lysozyme with glytathione-insulin transhydrogenase (thiol: protein-disulfide oxidoreductase): dependence upon conformation
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Insulin degradation XXIII. Distribution of glutathione-insulin transhydrogenase in isolated rat hepatocytes as studied by immuno-ferritin and electron microscopy
1 reference
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Crossref
reference URL
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7 January 2021
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IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Nuclear internalisation and DNA binding activities of interleukin-1, interleukin-1 receptor and interleukin-1/receptor complexes
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Dual mode of signal transduction by externally added acidic fibroblast growth factor
1 reference
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Crossref
reference URL
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7 January 2021
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Role of the transmembrane domain and flanking amino acids in internalization and down-regulation of the insulin receptor
1 reference
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Crossref
reference URL
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7 January 2021
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Enhancement or inhibition of insulin signaling by insulin receptor substrate 1 is cell context dependent
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Analysis of endogenous and exogenous nuclear translocation of fibroblast growth factor-1 in NIH 3T3 cells
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Translocation of epidermal growth factor to the hepatocyte nucleus during rat liver regeneration
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Identifiers
DOI
10.1016/S0074-7696(08)62479-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed publication ID
9127955
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9127955
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9127955%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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